Search results for "Crystal"

showing 10 items of 22886 documents

5-Carbonyl-1,3-oxazine-2,4-diones from N-Cyanosulfoximines and Meldrum’s Acid Derivatives

2020

At elevated temperatures, N-cyanosulfoximines react with Meldrum’s acid derivatives to give sulfoximines with N-bound 5-carbonyl-1,3-oxazine-2,4-dione groups. A representative product was characterized by single-crystal X-ray structure analysis. The product formation involves an unexpected molecular reorientation requiring several sequential bond-forming and -cleaving processes. peerReviewed

crystal structurekemiallinen synteesicyclizationaddition reactionskemialliset reaktiotreaction productsrikkiyhdisteetchemical reactionstyppiyhdisteetorgaaniset yhdisteet
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Two (E)-2-({[4-(dialkylamino)phenyl]- imino}methyl)-4-nitrophenols

2012

The slow evaporation of analytical NMR samples resulted in the formation of crystals of (E)-2-({[4-(dimethyl­amino)­phenyl]­imino}­methyl)-4-nitro­phenol, C15H15N3O3, (I), and (E)-2-({[4-(diethyl­amino)­phenyl]­imino}­methyl)-4-nitrophenol, C17H19N3O3, (II). Despite the small structural difference between these two N-salicylidene­aniline derivatives, they show different space groups and diverse mol­ecular packing. The mol­ecules of both compounds are close to being planar due to an intra­molecular O-H...N hydrogen bond. The 4-alkyl­amino-substituted benzene ring is inclined at an angle of 13.44 (19)° in (I) and 2.57 (8)° in (II) with respect to the 4-nitro-substituted phenol ring. Only very…

crystal structurekiderakenne2-({[4-(dialkyyliamino)fenyyli]- imino}metyyli)-4-nitrofenoli2-({[4-(dialkylamino)phenyl]- imino}methyl)-4-nitrophenol
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1-Diphenylphosphanyl-2-(diphenylphosphoryl)hydrazine

2018

The title compound, C24H22N2OP2, is an asymmetrically substituted hydrazine derivative bearing a phosphoryl and a phosphanyl substituent. The PNNP backbone has a torsion angle of −131.01 (8)°. In the crystal, molecules form centrosymmetric dimers by intermolecular N—H...O hydrogen bonds, which are further linked into a three-dimensional network by weak C—H...O and C—H...π interactions.

crystal structurelcsh:QD901-999hydrazinelcsh:CrystallographyPN chemistryIUCrData
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1,1-Bis(diphenylphosphoryl)hydrazine

2018

The title compound, C24H22N2O2P2, contains a diphosphazane backbone, as well as a hydrazine entity. The P—N—P diphosphazane unit and the N-amine N atom are almost coplanar, and the O atoms of the Ph2P(O) units are oriented trans to each other with respect to the P...P axis. In the crystal, centrosymmetrically related molecules are linked into dimers by pairs of N—H...O hydrogen bonds, forming rings of graph-set motif R22(10).

crystal structurelcsh:QD901-999hydrazinelcsh:CrystallographydiphosphazaneIUCrData
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Crystal structures of (E)-3-(4-hydroxybenzylidene)chroman-4-one and (E)-3-(3-hydroxybenzylidene)-2-phenylchroman-4-one

2019

The synthesis and crystal structures of (E)-3-(4-hydroxybenzylidene)chroman-4-one, C16H12O3, I, and (E)-3-(3-hydroxybenzylidene)-2-phenylchroman-4-one, C22H16O3, II, are reported. These compounds are of interest with respect to biological activity. Both structures display intermolecular C—H...O and O—H...O hydrogen bonding, forming layers in the crystal lattice. The crystal structure of compound I is consolidated by π–π interactions. The lipophilicity (logP) was determined as it is one of the parameters qualifying compounds as potential drugs. The logP value for compound I is associated with a larger contribution of C...H interaction in the Hirshfeld surface.

crystal structurelipophilicity index010405 organic chemistryChemistryHydrogen bondGeneral ChemistryCrystal structure010402 general chemistryCondensed Matter Physicschromanone derivative01 natural sciences0104 chemical scienceslcsh:ChemistryCrystallographylcsh:QD1-999hirshfeld surface analysisLipophilicityHirshfeld surface analysisGeneral Materials Scienceflavanone derivativeActa Crystallographica Section E Crystallographic Communications
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Revisiting the bromination of 3β-hydroxycholest-5-ene with CBr4/PPh3 and the subsequent azidolysis of the resulting bromide, disparity in stereochemi…

2023

Cholesterol reacts under Appel conditions (CBr4/PPh3) to give 3,5-cholestadiene (elimination) and 3β-bromocholest-5-ene (substitution with retention of configuration). Thus, the bromination of cholesterol deviates from the stereochemistry of the standard Appel mechanism due to participation of the Δ5 π-electrons. In contrast, the subsequent azidolysis (NaN3/DMF) of 3β-bromocholest-5-ene proceeds predominantly by Walden inversion (SN2) affording 3α-azidocholest-5-ene. The structures of all relevant products were revealed by X-ray single crystal structure analyses, and the NMR data are in agreement to the reported ones. In light of these findings, we herein correct the previous stereochemical…

crystal structurelääkkeetazidolysisAppel reactionkolesterolilääkehoitocholesterolWalden inversion
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Crystal structure of 5-{3-[2,6-dimethyl- 4-(5-methyl-1,2,4-oxadiazol-3-yl)phenoxy]propyl}- N-(11-hydroxyundecyl)isoxazole-3-carboxamide hemihydrate

2015

The crystal structure and supra­molecular features of 5-{3-[2,6-dimethyl-4-(5-methyl-1,2,4-oxa­diazol-3-yl)phen­oxy]prop­yl}-N-(11-hy­droxy­undec­yl)isoxazole-3-carboxamide hemihydrate, a derivative of anti­viral ‘WIN compounds’, are reported.

crystal structuremedicine.drug_classOxadiazoleCarboxamideNanotechnologyCrystal structureDihedral angleRing (chemistry)Medicinal chemistryResearch Communicationschemistry.chemical_compoundmedicinePeptide bondGeneral Materials ScienceIsoxazoleta116oxa­diazoleCrystallographyChemistryHydrogen bondWIN derivativeisoxazoleGeneral ChemistryCondensed Matter PhysicsantiviralQD901-999anti­viraloxadiazoleActa Crystallographica Section E : Crystallographic Communications
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Crystal structure of tricarbonyl(μ-diphenylphosphido-κ2P:P)(methyldiphenylsilyl-κSi)bis(triphenylphosphane-κP)iron(II)platinum(0)(Fe—Pt)

2015

The title compound belongs to the large family of heterodinuclear phosphide-bridged complexes. The Fe—Pt bond is of 2.7738 (4) Å and there is an unprecedented arrangement of the silyl ligand in a trans-position with respect to the metal–metal vector in the family of phosphide-bridged iron–platinum heterobimetallics.

crystal structuremetal–metal bondSilylationStereochemistrychemistry.chemical_elementCrystal structureMedicinal chemistryResearch Communicationslcsh:Chemistrychemistry.chemical_compoundphosphido bridges[CHIM]Chemical SciencesGeneral Materials Sciencediphenylmethylsilyl ligandComputingMilieux_MISCELLANEOUSdi­phenyl­methyl­silyl ligandLigandTricarbonGeneral ChemistryCondensed Matter Physics3. Good healthiron complexeslcsh:QD1-999chemistryheterobimetallicsPlatinumplatinum complexesActa Crystallographica Section E Crystallographic Communications
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Substituent effects in nitro derivatives of carbazoles investigated by comparison of low-temperature crystallographic studies with density functional…

2014

The crystal structure of 9H-carbazole, C12H9N, (I), has been redetermined at low temperature for use as a reference structure in a comparative study with the structures of 1-nitro-9H-carbazole, C12H8N2O2, (II), and 9-nitrocarbazole, C12H8N2O2, (III). The molecule of (I) has crystallographically imposed mirror symmetry (Z′ = 0.5). All three solid-state structures are slightly nonplanar, the dihedral angles between the planes of the arene and pyrrole rings ranging from 0.40 (7)° in (III) to 1.82 (18)° in (II). Nevertheless, a density functional theory (DFT) study predicts completely planar conformations for the isolated molecules. To estimate the influence of nitro-group substitution on aroma…

crystal structuremolecular electronicsSubstituentStackingElectronsbiological activityCrystal structureDihedral angleCrystallography X-RayDFT calculationsInorganic Chemistrychemistry.chemical_compoundDelocalized electronHOMA indexMaterials ChemistryPhysical and Theoretical ChemistryMolecular StructureHydrogen bondTemperatureHydrogen BondingAromaticityNitro CompoundsCondensed Matter PhysicsCrystallographycarbazoleselectron-withdrawing effectschemistryQuantum TheoryDensity functional theoryActa Crystallographica Section C-Structural Chemistry
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Tetracarbonyl[N-(diphenylphosphanyl-κP)-N,N′-diisopropyl-P-phenylphosphorus diamide-κP]molybdenum(0) with an unknown solvent

2018

The title complex, [Mo(C24H30N2P2)(CO)4], contains a molybdenum centre bearing a P,P′-cis-chelating Ph2PN(iPr)P(Ph)NH(iPr) and four carbonyl ligands in a distorted octahedral coordination geometry. This results in a nearly planar four-membered metallacycle. In the crystal, molecules are linked by N—H...O and C—H...O hydrogen bonds to form layers parallel to the ac plane. For the final refinement, the contributions of disordered solvent molecules were removed from the diffraction data with SQUEEZE in PLATON [Spek (2015). Acta Cryst. C71, 9–18]. The given chemical formula and other crystal data do not take into account the unknown solvent molecule(s).

crystal structuremolybdenumlcsh:QD901-999lcsh:CrystallographydiphosphazaneIUCrData
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