Search results for "CuO"
showing 10 items of 497 documents
Distance of matter inside an Einstein-Strauss vacuole
2008
Root vacuolar sequestration and suberization are prominent responses of Pistacia spp. rootstocks during salinity stress
2021
Abstract Understanding the mechanisms of stress tolerance in diverse species is needed to enhance crop performance under conditions such as high salinity. Plant roots, in particular in grafted agricultural crops, can function as a boundary against external stresses in order to maintain plant fitness. However, limited information exists for salinity stress responses of woody species and their rootstocks. Pistachio (Pistacia spp.) is a tree nut crop with relatively high salinity tolerance as well as high genetic heterogeneity. In this study, we used a microscopy‐based approach to investigate the cellular and structural responses to salinity stress in the roots of two pistachio rootstocks, Pis…
Prassi teatrale e didattica inclusiva: una prospettiva di intervento formativo
2017
Il vistoso cambiamento di paradigma pedagogico, registrato negli ultimi anni in Italia, ha visto il passaggio dal concetto di integrazione al costrutto più complesso di inclusione, secondo cui non è richiesto tanto l’adattamento del soggetto disabile al contesto scolastico, bensì il contrario. Secondo Gardou (2015), la categoria di “accessibilità” costituisce l’assioma di ogni pratica inclusiva e includere equivale a rendere possibile a tutti l’accesso alla formazione, alla vita sociale, culturale e civile rispettando i bisogni particolari di ciascuno. A ciò si aggiunga che «[…] è doveroso e necessario capire come favorire le “integrazioni” nella classe […] ogni singolo ragazzo porta specif…
Primo Levi nelle antologie
2021
Primo Levi è ormai nel canone internazionale degli scrittori, tuttavia la sua produzione letteraria è ancora prevalentemente (ma non del tutto) considerata nella sua veste testimoniale. A cento anni dalla nascita dello scrittore, si indaga la ricezione delle opere leviane nella manualistica scolastica attraverso l’esame di alcuni testi per le scuole superiori pubblicati dal Duemila a oggi. Si ragiona sul tipo di brani antologizzati e sulle opere riportate con più frequenza. Nella proposta antologica dei manuali scolastici si colgono le metamorfosi subite dall’immagine dello scrittore.
La saga de las cuotas
1996
Tributyltin(IV) ferulate, a novel synthetic ferulic acid derivative, induces autophagic cell death in colon cancer cells: From chemical synthesis to …
2020
Ferulic acid (FA) is a natural phenolic phytochemical that has low toxicity and exhibits therapeutic effects against various diseases, behaving as an antioxidant. FA also displays modest antitumor properties that have been reported at relatively high concentrations. With the aim of improving the anti-tumor efficacy of FA, we synthesized the novel compound tributyltin(IV) ferulate (TBT-F). The coordination environment at the tin center was investigated spectroscopically. Following synthesis, chemical characterization and computational analysis, we evaluated TBT-F effects in colon cancer cells. The results showed that TBT-F, at nanomolar range concentrations, was capable of reducing the viabi…
Out for a Walk Along the Secretory Pathway During Programmed Cell Death
2015
This chapter provides a comprehensive updated analysis on the role of the secretory pathway in the orchestration of cell’s demise, an emerging and promising research topic in the field of plant programmed cell death (PCD). Since my first review on this topic, a plethora of data has been published supporting the concept that endomembrane system-forming subcellular compartments cooperate to coordinate cellular responses to developmental and environmental cues and thereby can dictate a cell’s ultimate fate. Thus, the early secretory pathway, encompassing the endoplasmic reticulum and Golgi apparatus, can be involved in the perception of extrinsic and intrinsic stimuli. It can also be an active…
Mode of cell death induction by pharmacological Vacuolar H+-ATPase (V-ATPase) inhibition.
2012
The vacuolar H+-ATPase (V-ATPase), a multisubunit proton pump, has come into focus as an attractive target in cancer invasion. However, little is known about the role of V-ATPase in cell death, and especially the underlying mechanisms remain mostly unknown. We used the myxobacterial macrolide archazolid B, a potent inhibitor of the V-ATPase, as an experimental drug as well as a chemical tool to decipher V-ATPase-related cell death signaling. We found that archazolid induced apoptosis in highly invasive tumor cells at nanomolar concentrations which was executed by the mitochondrial pathway. Prior to apoptosis induction archazolid led to the activation of a cellular stress response including …
Death of mitochondria during programmed cell death of leaf mesophyll cells
2005
The role of plant mitochondria in the programmed cell death (PCD) is widely discussed. However, spectrum and sequence of mitochondrial structural changes during different types of PCD in leaves are poorly described. Pea, cucumber and rye plants were grown under controlled growing conditions. A part of them were sprinkled with ethylene releaser to accelerate cell death. During yellowing the palisade parenchyma mitochondria were attracted to nuclear envelope. Mitochondrial matrix became electron translucent. Mitochondria entered vacuole by invagination of tonoplast and formed multivesicular bodies. Ethephon treatment increased the frequency of sticking of mitochondria to the nuclear envelope …
Acute cytotoxicity and apoptotic effects after l-Pam exposure in different cocultures of the proximal and distal respiratory system.
2009
Abstract Sulphur and nitrogen mustard are strong alkylating agents which can cause after inhalation acute lung injury in the larynx, trachea and large bronchi and can lead to alveolar edema. In our study we tested the N-Lost l -Phenylalanine Mustard ( l -Pam). Therefore we seeded the alveolar type II cell line NCI H441 on the upper membrane of a Transwell filter plate and the endothelial cell line ISO-Has-1 on the lower side of the membrane for the alveolar model and combined the human bronchial explant-outgrowth cells and fibroblasts in the bronchial model and exposed both models with various concentrations of l -Pam. Treatment with l -Pam led to a concentration-dependent decrease of the t…