Search results for "Cuneus"

showing 5 items of 15 documents

FDG-PET mapping the brain substrates of visuo-constructive processing in Alzheimer´s disease

2010

The anatomical basis of visuo-constructive impairment in AD is widely unexplored. FDG-PET can be used to determine functional neuronal networks underlying specific cognitive performance in the human brain. In the present study, we determined the pattern of cortical metabolism that was associated with visuo-constructive performance in AD. We employed two widely used visuo-constructive tests that differ in their demand on visual perception and processing capacity. Resting state FDG-PET scans were obtained in 29 probable AD patients, and cognitive tests were administered. We made a voxel-based regression analysis of FDG uptake to scores in visual test performance, using the SPM5 software. Perf…

MaleVisual perceptiongenetic structuresPrecuneusNeuropsychological TestsBrain mappingVisual processingFolic AcidAlzheimer DiseaseFluorodeoxyglucose F18medicineHumansBiological PsychiatryAgedAged 80 and overBrain MappingVisual testCognitive neuroscience of visual object recognitionBrainLimbic lobeHuman brainMiddle AgedVitamin B 12Psychiatry and Mental healthmedicine.anatomical_structurenervous systemPositron-Emission TomographyLinear ModelsVisual PerceptionFemaleMental Status SchedulePsychologyNeurosciencePhotic StimulationJournal of Psychiatric Research
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Localization of Brain Networks Engaged by the Sustained Attention to Response Task Provides Quantitative Markers of Executive Impairment in Amyotroph…

2020

Abstract Objective: To identify cortical regions engaged during the sustained attention to response task (SART) and characterize changes in their activity associated with the neurodegenerative condition amyotrophic lateral sclerosis (ALS). Methods: High-density electroencephalography (EEG) was recorded from 33 controls and 23 ALS patients during a SART paradigm. Differences in associated event-related potential peaks were measured for Go and NoGo trials. Sources active during these peaks were localized, and ALS-associated differences were quantified. Results: Go and NoGo N2 and P3 peak sources were localized to the left primary motor cortex, bilateral dorsolateral prefrontal cortex (DLPFC),…

AdultMaleCognitive NeurosciencePosterior parietal cortexElectroencephalographybehavioral disciplines and activities050105 experimental psychologyExecutive Function03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicinemedicineHumansAttention0501 psychology and cognitive sciencesAcademicSubjects/MED00385Amyotrophic lateral sclerosisEvoked PotentialsAgedmedicine.diagnostic_testAcademicSubjects/SCI01870business.industryAmyotrophic Lateral Sclerosis05 social sciencesBrainElectroencephalographyInferior parietal lobuleCognitionMiddle Agedmedicine.diseaseLeft primary motor cortexDorsolateral prefrontal cortexmedicine.anatomical_structureFemaleAcademicSubjects/MED00310Nerve NetRight precuneusCorrigendumbusinessNeurosciencepsychological phenomena and processes030217 neurology & neurosurgeryCerebral Cortex
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Verbal learning and memory and their associations with brain morphology and illness course in schizophrenia spectrum psychoses.

2012

The California Verbal Learning Test and structural brain imaging were administered to 57 subjects with schizophrenia spectrum disorders and 94 controls in a general population sample. Cases had lower semantic cluster scores. Poorer verbal memory strategies were associated with longer duration of illness and heavier use of antipsychotic medication. After controlling for duration of illness, sex, and total gray matter, poorer verbal memory was associated with lower gray matter volume in the cingulate cortex, juxtapositional lobule, right superior temporal gyrus, and precuneus. After controlling for use of antipsychotic medication, there was an association between higher serial clustering and …

Cingulate cortexAdultMalemedicine.medical_specialtyPsychosisPrecuneusNeuroimagingAudiologyNeuropsychological TestsVerbal learningbehavioral disciplines and activitiesMemorymedicineImage Processing Computer-AssistedHumansEffects of sleep deprivation on cognitive performancePsychiatryta515Psychiatric Status Rating ScalesCalifornia Verbal Learning TestWorking memoryBrainVerbal Learningmedicine.diseaseClinical Psychologymedicine.anatomical_structureNeurologyPsychotic DisordersDisease ProgressionSchizophreniaFemaleSchizophrenic PsychologyNeurology (clinical)Verbal memoryPsychologyJournal of clinical and experimental neuropsychology
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Neuroanatomical changes in early Parkinson’s disease with mild cognitive impairment: a VBM study; the Parkinson’s Disease Cognitive Impairment Study …

2021

Introduction: Mild cognitive impairment (MCI) is common in Parkinson’s disease (PD), but the underlying pathological mechanism has not been fully understood. Voxel-based morphometry could be used to evaluate regional atrophy and its relationship with cognitive performances in early PD-MCI. Patients and Methods: One hundred and six patients with PD were recruited from a larger cohort of patients, the Parkinson’s Disease Cognitive Impairment Study (PaCoS). Subject underwent a T1-3D MRI and a complete clinical and neuropsychological evaluation. Patients were divided into PD with normal cognition (PD-NC) and PD-MCI according to the MDS level II criteria–modified for PD-MCI. A subgroup of early …

medicine.medical_specialtyParkinson's diseasePrecuneusInferior frontal gyrusDermatologyNeuropsychological TestsAudiologybehavioral disciplines and activitiesVoxel-based morphometry (VBM)Angular gyrus03 medical and health sciences0302 clinical medicinemental disordersmedicineHumansCognitive DysfunctionMagnetic resonance imaging (MRI)030212 general & internal medicineGray MatterMild cognitive impairment (MCI)business.industryNeuropsychologyBrainSettore MED/37 - NeuroradiologiaGeneral MedicineFrontal gyrusmedicine.diseaseMagnetic Resonance ImagingParkinson diseasePsychiatry and Mental healthmedicine.anatomical_structurenervous systemSuperior frontal gyrusSettore MED/26 - NeurologiaNeurology (clinical)Settore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessMild cognitive impairment (MCI)030217 neurology & neurosurgeryNeurological Sciences
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Asymmetric modulation of human visual cortex activity during 10 degrees lateral gaze (fMRI study).

2005

We used BOLD fMRI to study the differential effects of the direction of gaze on the visual and the ocular motor systems. Fixation of a target straight ahead was compared to fixation of a target 10 degrees to the right and 10 degrees to the left from gaze straight ahead, and to eyes open in complete darkness in thirteen healthy volunteers. While retinotopic coordinates remained the same in all fixation conditions, the fixation target shifted with respect to a head-centered frame of reference. During lateral fixation, deactivations in higher-order visual areas (one ventral cluster in the lingual and fusiform gyri and one dorsal cluster in the postero-superior cuneus) and, as a trend, activati…

AdultMalegenetic structuresCognitive NeuroscienceFixation OcularFunctional LateralityCuneusVisual processingmedicineImage Processing Computer-AssistedHumansComputer visionVisual Cortexbusiness.industryEye movementDarknessGazeMagnetic Resonance Imagingeye diseasesOxygenmedicine.anatomical_structureVisual cortexNeurologyVisuospatial perceptionData Interpretation StatisticalLateralityFixation (visual)FemaleArtificial intelligencebusinessPsychologyNeuroscienceNeuroImage
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