6533b82bfe1ef96bd128d6a7
RESEARCH PRODUCT
Cognitive benefits of exercise interventions: an fMRI activation likelihood estimation meta-analysis.
Arthur F. KramerBen Klugah-brownLiye ZouBenjamin BeckerStéphane PerreyNicola VeroneseQian YuFabian HeroldNotger G. MüllerYanjie Zhangsubject
medicine.medical_specialtyHistologyNeurology[SDV]Life Sciences [q-bio]PrecuneusNetworkPhysical exerciseSubgroup analysisExercise · Cognition · Brain health · Network050105 experimental psychology[SCCO]Cognitive science03 medical and health sciencesphysiology [Brain]methods [Magnetic Resonance Imaging]0302 clinical medicinePhysical medicine and rehabilitationCognitionNeuroimagingphysiopathology [Nerve Net]medicineHumans0501 psychology and cognitive sciencesddc:610ExerciseComputingMilieux_MISCELLANEOUSDefault mode networkLikelihood Functionsbusiness.industryGeneral Neuroscience05 social sciencesphysiology [Cognition]BrainCognitionMagnetic Resonance Imaging[STAT]Statistics [stat]medicine.anatomical_structureMeta-analysisBrain healthphysiology [Nerve Net]sense organsAnatomyNerve Netbusiness030217 neurology & neurosurgerydescription
Despite a growing number of functional MRI studies reporting exercise-induced changes during cognitive processing, a systematic determination of the underlying neurobiological pathways is currently lacking. To this end, our neuroimaging meta-analysis included 20 studies and investigated the influence of physical exercise on cognition-related functional brain activation. The overall meta-analysis encompassing all experiments revealed physical exercise-induced changes in the left parietal lobe during cognitive processing. Subgroup analysis further revealed that in the younger-age group (< 35 years old) physical exercise induced more widespread changes in the right hemisphere, whereas in the older-age group (≥ 35 years old) exercise-induced changes were restricted to the left parietal lobe. Subgroup analysis for intervention duration showed that shorter exercise interventions induced changes in regions connected with frontoparietal and default mode networks, whereas regions exhibiting effects of longer interventions connected with frontoparietal and dorsal attention networks. Our findings suggest that physical exercise interventions lead to changes in functional activation patterns primarily located in precuneus and associated with frontoparietal, dorsal attention and default mode networks. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-04-01 | Brain structurefunction |