Search results for "Cyanide"

showing 10 items of 180 documents

The Unique Versatility of the Double Metal Cyanide (DMC) Catalyst: Introducing Siloxane Segments to Polypropylene Oxide by Ring-Opening Copolymerizat…

2020

The combination of hydrophobic polydimethylsiloxane (PDMS) blocks with hydrophilic polyether segments plays a key role for silicone surfactants. Capitalizing on the double metal cyanide (DMC) catalyst, the direct (i.e., statistical) copolymerization of cyclic siloxanes and epoxides is shown to be feasible. The solvent-free one-pot copolymerization of hexamethylcyclotrisiloxane and propylene oxide results in the formation of gradient propylene oxide (PPO)-PDMS copolymers. Copolymers with up to 46% siloxane content with low dispersities (Ð < 1.2) are obtained in the molecular weight range of 2100-2900 g mol-1 . The polymerization kinetics are investigated by pressure monitoring and in situ 1 …

Materials sciencePolymers and PlasticsSiloxanesOxide02 engineering and technology010402 general chemistryPolypropylenes01 natural sciencesRing-opening polymerizationPolymerizationContact anglechemistry.chemical_compoundSiliconeMaterials ChemistryCopolymerPropylene oxideCyanidesPolydimethylsiloxaneOrganic ChemistryOxides021001 nanoscience & nanotechnology0104 chemical scienceschemistryChemical engineeringSiloxane0210 nano-technologyMacromolecular rapid communications
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Design of single cyanide-bridged tetranuclear bimetallic rectangles exhibiting ferromagnetic coupling

2005

Abstract The cyanide-bridged tetranuclear bimetallic rectangles ( XPh 4 ) 4 [ Fe 2 III Cu 2 II ( μ - CN ) 4 ( CN ) 8 ( L ) 2 ] · n H 2 O [X = P (1) and As (2); L = bpcam (1) and bpca (2); n = 4 (1) and 0 (2)] have been prepared and their crystal structures were characterized by single crystal X-ray diffraction; 1 exhibits intramolecular ferromagnetic interactions (J1 = +3.7 cm−1 and J2 = +7.0 cm−1, H = - J 1 [ S Fe ( 1 ) · S Cu ( 1 ) + S Fe ( 1 a ) · S Cu ( 1 a ) ] − J 2 [ S Fe ( 1 ) · S Cu ( 1 a ) + S Fe ( 1 a ) · S Cu ( 1 ) ] + D [ S Fe ( 1 ) z 2 + S Fe ( 1 a ) z 2 ] ) leading to a low-lying S = 2 spin state.

Materials scienceSpin statesCyanideCrystal structureCoupling (probability)Inorganic ChemistryCrystallographychemistry.chemical_compoundFerromagnetismchemistryIntramolecular forceMaterials ChemistryPhysical and Theoretical ChemistrySingle crystalBimetallic stripInorganic Chemistry Communications
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Guest Effect on Nanopatterned Spin-Crossover Thin Films

2011

International audience; Nanopatterned thin films of the metal–organic framework {Fe(bpac)[Pt(CN)4]} (bpac=bis(4‐pyridyl)acetylene) are elaborated by the combination of a sequential assembly process and a lithographic method. Raman microspectroscopy is used to probe the temperature dependence of the spin state of the iron(II) ions in the films (40–90 nm in thickness), and reveals an incomplete but cooperative spin transition comparable to that of the bulk material. Adsorption/desorption of pyridine guest molecules is found to have a substantial influence on the spin‐crossover properties of the thin layers. This interplay between host–guest and spin‐crossover properties in thin films and nano…

Materials scienceSpin statesSpin transitionNanotechnology02 engineering and technologyMicroscopy Atomic ForceSpectrum Analysis Raman010402 general chemistry01 natural sciencesBiomaterialssymbols.namesakeSpin crossoverMetals HeavyDesorptionTransition TemperatureGeneral Materials ScienceThin film[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/MicroelectronicsCyanidesThin layersTransition temperatureGeneral Chemistry021001 nanoscience & nanotechnologyNanostructures0104 chemical sciencessymbolsPhysical chemistrySpin Labels0210 nano-technologyRaman spectroscopyBiotechnology
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Fluorescent styrylpyrylium probes for the imaging of mitochondria in live cells

2021

Eight styrylpyrylium tetrafluoroborate salts have been synthesized and fully optically characterized by UV-vis absorption and fluorescence steady-state/time-resolved spectroscopies. The new dyes exhibit strong emission bands with yellow–orange colours, depending on the substituents present in the structure. Notably, the Stokes shift recorded for some of them exceeds 100 nm, a very valuable feature for biological imaging. Four of them have been assayed as biological imaging agents by confocal laser scanning microscopy (CLSM) in the human hepatoma cell line Hep3B. It has been found that all the compounds efficiently stain intracellular structures which have been identified as mitochondria thr…

Membrane potentialCarbonyl Cyanide m-Chlorophenyl HydrazoneChemistryOrganic ChemistryColocalizationMitochondrionBiochemistryFluorescenceImaging agentsymbols.namesakeStokes shiftsymbolsBiophysicsPhysical and Theoretical ChemistryBiological imagingIntracellular
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Synthesis and antibacterial activity of iron-hexacyanocobaltate nanoparticles.

2018

This paper deals with the synthesis and characterization of iron-hexacyanocobaltate (FeHCC) and its antibacterial properties. The nanoparticles were prepared by a facile co-precipitation technique. Crystal structure, particle morphology, and elemental composition were determined using X-ray Powder Diffraction, X-ray fluorescence spectroscopy, Transmission Electron Microscopy (TEM), and Infrared Spectroscopy (IR). The antibacterial activity of the FeHCC nanoparticles was tested against Escherichia coli and Staphylococcus aureus as models for Gram-negative and Gram-positive bacteria, respectively, by bacterial counting method and microscopic visualization (TEM, FEG-SEM, and fluorescence micro…

Metal-hexacyanoferrateStaphylococcus aureusIronColony Count MicrobialInfrared spectroscopyNanoparticleMetal Nanoparticles02 engineering and technologyMicrobial Sensitivity TestsBacterial growth010402 general chemistrymedicine.disease_cause01 natural sciencesBiochemistryFluorescence spectroscopyInorganic ChemistryMicroscopy Electron TransmissionmedicineFluorescence microscopeEscherichia coliEscherichia coliCyanidesChemistryIron-hexacyanocobaltateCobalt021001 nanoscience & nanotechnology0104 chemical sciencesAnti-Bacterial AgentsSpectrometry FluorescenceStaphylococcus aureuMicroscopy Electron ScanningAntibacterial activity0210 nano-technologyAntibacterial activityReactive Oxygen SpeciesNuclear chemistryMacromoleculeJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry
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Reactive oxygen species derived from the mitochondrial respiratory chain are not responsible for the basal levels of oxidative base modifications obs…

2004

The mitochondrial electron transport chain (ETC) is the most important source of reactive oxygen species (ROS) in mammalian cells. To assess its relevance to the endogenous generation of oxidative DNA damage in the nucleus, we have compared the background (steady-state) levels of oxidative DNA base modifications sensitive to the repair glycosylase Fpg (mostly 7,8-dihydro-8-oxoguanine) in wild-type HeLa cells and HeLa rho0 cells. The latter are depleted of mitochondrial DNA and therefore are unable to produce ROS in the ETC. Although the levels of ROS measured by flow cytometry and redox-sensitive probes in rho0 cells were only 10-15% those of wild-type cells, steady-state levels of oxidativ…

Mitochondrial ROSCarbonyl Cyanide m-Chlorophenyl HydrazoneMitochondrial DNADNA damageCells[SDV]Life Sciences [q-bio]Oxidative phosphorylationMitochondrionBiologyBiochemistryElectron Transport03 medical and health sciences0302 clinical medicinePhysiology (medical)AnimalsHumansComputingMilieux_MISCELLANEOUS030304 developmental biologyCell Nucleus0303 health sciencesGuanosineNucleotidesEscherichia coli ProteinsDNAFlow CytometryMitochondriaNuclear DNAMitochondrial respiratory chainDNA-Formamidopyrimidine GlycosylaseBiochemistryDNA glycosylaseMacrolidesReactive Oxygen SpeciesOxidation-Reduction030217 neurology & neurosurgeryDNA DamageHeLa Cells
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Reaction between Indazole and Pd-Bound Isocyanides-A Theoretical Mechanistic Study

2018

The mechanism of the addition of indazole (Ind)&mdash

Models Molecular3003Activation of small moleculesIndazolesisocyanideIsocyanidePharmaceutical ScienceDFT calculationProtonation010402 general chemistryDFT calculationsactivation of small molecule01 natural sciencesMedicinal chemistryArticleAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compoundDeprotonationNucleophilelcsh:Organic chemistryTheoreticalModelsDrug DiscoveryNitrilesPhysical and Theoretical ChemistryMechanical PhenomenaIndazoleNucleophilic additionCyanidesMolecular Structure010405 organic chemistrynitrileDrug Discovery3003 Pharmaceutical ScienceOrganic ChemistryRegioselectivityMolecularIsocyanidesModels TheoreticalTautomer0104 chemical sciencesnucleophilic additionchemistryChemistry (miscellaneous)Settore CHIM/03 - Chimica Generale E InorganicaMolecular Medicinereaction mechanismActivation of small molecules; DFT calculations; Isocyanides; Nitriles; Nucleophilic addition; Reaction mechanism; Cyanides; Indazoles; Models Molecular; Molecular Structure; Palladium; Mechanical Phenomena; Models Theoretical; Analytical Chemistry; Chemistry (miscellaneous); Molecular Medicine; 3003; Drug Discovery3003 Pharmaceutical Science; Physical and Theoretical Chemistry; Organic ChemistryPalladium
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A Germanium Isocyanide Complex Featuring (n -> π*) Back-Bonding and Its Conversion to a Hydride/Cyanide Product via C–H Bond Activation under Mild Co…

2012

Reaction of the diarylgermylene Ge(Ar(Me(6)))(2) [Ar(Me(6)) = C(6)H(3)-2,6-(C(6)H(2)-2,4,6-(CH(3))(3))(2)] with tert-butyl isocyanide gave the Lewis adduct species (Ar(Me(6)))(2)GeCNBu(t), in which the isocyanide ligand displays a decreased C-N stretching frequency consistent with an n → π* back-bonding interaction. Density functional theory confirmed that the HOMO is a Ge-C bonding combination between the lone pair of electrons on the germanium atom and the C-N π* orbital of the isocyanide ligand. The complex undergoes facile C-H bond activation to produce a new diarylgermanium hydride/cyanide species and isobutene via heterolytic cleavage of the N-Bu(t) bond.

Models MolecularC h bondCyanidesLigandHydrideGermaniumIsocyanideCyanidechemistry.chemical_elementGermaniumHydrogen BondingGeneral ChemistryPhotochemistryCrystallography X-RayBiochemistryMedicinal chemistryCatalysisAdductchemistry.chemical_compoundColloid and Surface ChemistrychemistryOrganometallic Compoundsta116Pi backbondingHydrogenJournal of the American Chemical Society
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Confined growth of cyanide-based magnets in two dimensions

2010

Herein we report the first hybrid magnetic material resulting from the intercalation of a cyanide-based molecular magnet into a solid-state layered host. More specifically, the use of a diamagnetic cationic Zn(II)-Al(lII) layered double hydroxide host allows for the formation of an anionic two-dimensional ferromagnetic Ni(II)-Cr(III) Prussian Blue analogue, from the templated assembly of its ionic molecular components in the confined interlamellar space offered by the inorganic host.

Molecular magnetsCyanideIntercalation (chemistry)Inorganic chemistry02 engineering and technologyequipment and supplies010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesInorganic Chemistrychemistry.chemical_compoundchemistryChemical physicsMagnetDiamagnetismPhysical and Theoretical Chemistry0210 nano-technologyhuman activitiesInorganic Chemistry
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Mechanism of Reaction of Melatonin with Human Myeloperoxidase

2001

Recently, it was suggested that melatonin (N-acetyl-5-methoxytryptamine) is oxidized by activated neutrophils in a reaction most probably involving myeloperoxidase (Biochem. Biophys. Res. Commun. (2000) 279, 657-662). Myeloperoxidase (MPO) is the most abundant protein of neutrophils and is involved in killing invading pathogens. To clarify if melatonin is a substrate of MPO, we investigated the oxidation of melatonin by its redox intermediates compounds I and II using transient-state spectral and kinetic measurements at 25 degrees C. Spectral and kinetic analysis revealed that both compound I and compound II oxidize melatonin via one-electron processes. The second-order rate constant measur…

NeutrophilsStereochemistryBiophysicsElectron donorIn Vitro TechniquesBiochemistryRedoxMedicinal chemistrySubstrate SpecificityElectron TransportSuperoxide dismutaseMelatoninchemistry.chemical_compoundReaction rate constantChloridesmedicineHumansMolecular BiologySodium cyanideMelatoninPeroxidasebiologyCyclohexanonesChemistryCell BiologyHydrogen-Ion ConcentrationKineticsSpectrophotometryMyeloperoxidasebiology.proteinFerricOxidation-Reductionmedicine.drugBiochemical and Biophysical Research Communications
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