Search results for "Cyclin"

Treatment of aqueous solutions of oxytetracycline by different electrochemical approaches: anodic oxidation, pressurized electro-Fenton and oxidation…

2023

The tetracycline group (TCs) includes the most common antibiotics for treatment of both human and animal infections. TCs are resistant to biological degradation; hence, conventional wastewater treatments are unable to remove these contaminants. Here, the utilization of different electrochemical processes, such as electro-Fenton (EF), direct anodic oxidation (AO) and indirect oxidation by electrogenerated active chlorine (EAC), for the treatment of aqueous solutions of oxytetracycline (OTC), which is one of the TCs, was studied. The effect of various operating conditions was evaluated to optimize the selected processes. EAC gave the fastest abatement of OTC, but the lowest removal of TOC and…

No effect of Cimicifuga racemosa extract on serum interleukin-6 levels and prostacyclin production by human endothelial cells

2009

The categorization of amateur cyclists as research participants: findings from an observational study.

2018

Sampling bias is an issue for research involving cyclists. The heterogeneity of cyclist populations, on the basis of skill level and riding purpose, can generate incorrect inferences about one specific segment of the population of interest. In addition, a more accurate categorization would be helpful when physiological parameters are not available. This study proposes using self-reported data to categorize amateur cyclist types by varying skill levels and riding purposes, therefore improving sample selection in experimental studies. A total of 986 cyclists completed an online questionnaire between February and October 2016. Two-step cluster analyses were performed to generate distinct group…

Diritto d’asilo. Accessibilità e riciclo dell’ex Asilo Biondo a Danisinni, Palermo

2022

There are many virtuous initiatives, national and international, which, starting from school buildings, have aimed at redeveloping some degraded urban spaces through paths aimed at increasing civic sense and social and environmental sensitivity in pupils, parents and citizens. . Reopening schools in neighborhoods characterized by a high school dropout was the goal of the research aimed at making accessible the paths and spaces in school buildings and starting urban and architectural recycling projects in waiting places. The research thus proposed field work in opposition to an ongoing process carried out by the municipal administration of Palermo which identified precisely in obsolete or ab…

Como as práticas ecológicas e o desperdício de alimentos influenciam o capital de marca do restaurante?

2020

Resumen El presente trabajo tuvo por objetivo evaluar la incidencia de las prácticas verdes, la innovación sostenible y el manejo del desperdicio alimentario en la construcción del capital de marca de los restaurantes. A partir de una investigación cuantitativa dirigida a responsables de restaurantes en Ecuador, se obtuvieron 120 cuestionarios válidos que permitieron estimar un modelo de ecuaciones estructurales a través de la regresión de mínimos cuadrados parciales. Los resultados obtenidos evidencian que las prácticas verdes orientadas a la formación del empleado y la innovación sostenible contribuyen significativamente a la reducción del desperdicio alimentario, que, a su vez, junto a l…

p27Kip1participates in the regulation of endoreplication in differentiating chick retinal ganglion cells

2015

Nuclear DNA duplication in the absence of cell division (i.e. endoreplication) leads to somatic polyploidy in eukaryotic cells. In contrast to some invertebrate neurons, whose nuclei may contain up to 200,000-fold the normal haploid DNA amount (C), polyploid neurons in higher vertebrates show only 4C DNA content. To explore the mechanism that prevents extra rounds of DNA synthesis in these latter cells we focused on the chick retina, where a population of tetraploid retinal ganglion cells (RGCs) has been described. We show that differentiating chick RGCs that express the neurotrophic receptors p75 and TrkB while lacking retinoblastoma protein, a feature of tetraploid RGCs, also express p27K…

Integrating Circularity in the Sustainability Assessment of Asphalt Mixtures

2020

Rising concerns about the impacts that the road engineering industry is imposing to the environment have redirected national road authorities to firmly re-consider the sustainability implications of their operations. Lately, though, sustainability has established a forceful correlation with the Circular Economy and its principles. The road engineering industry, therefore, is moving towards more circular approaches. However, this is occurring without the assessment of the potential impacts of such a transition. For this reason, in this study, a composite indicator, namely, Environmental Sustainability and Circularity indicator (ESCi), for investigating the potential effects that increased ci…

The telomeric Cdc13-Stn1-Ten1 complex regulates RNA polymerase II transcription

2019

Advance article.

Rot1 plays an antagonistic role to Clb2 in actin cytoskeleton dynamics throughout the cell cycle.

2007

ROT1 is an essential gene whose inactivation causes defects in cell cycle progression and morphogenesis in budding yeast. Rot1 affects the actin cytoskeleton during the cell cycle at two levels. First, it is required for the maintenance of apical growth during bud growth. Second, Rot1 is necessary to polarize actin cytoskeleton to the neck region at the end of mitosis; because of this defect, rot1 cells do not properly form a septum to complete cell division. The inability to polarize the actin cytoskeleton at the end of mitosis is not due to a defect in the recruitment of the polarisome scaffold protein Spa2 or the actin cytoskeleton regulators Cdc42 and Cdc24 in the neck region. Previous …

Functional Connection Between the Clb5 Cyclin, the Protein Kinase C Pathway and the Swi4 Transcription Factor in Saccharomyces cerevisiae

2005

Abstract The rsf12 mutation was isolated in a synthetic lethal screen for genes functionally interacting with Swi4. RSF12 is CLB5. The clb5 swi4 mutant cells arrest at G2/M due to the activation of the DNA-damage checkpoint. Defects in DNA integrity was confirmed by the increased rates of chromosome loss and mitotic recombination. Other results suggest the presence of additional defects related to morphogenesis. Interestingly, genes of the PKC pathway rescue the growth defect of clb5 swi4, and pkc1 and slt2 mutations are synthetic lethal with clb5, pointing to a connection between Clb5, the PKC pathway, and Swi4. Different observations suggest that like Clb5, the PKC pathway and Swi4 are in…