Search results for "Cyclin"
showing 10 items of 1021 documents
From intensive car-parenting to enabling childhood velonomy? Explaining parents’ representations of children’s leisure mobilities
2023
Intensive parenting has become a key term for analysing the pressures and priorities of contemporary western parenting culture. For mobility studies it provides a discursive framework for understanding why children’s leisure has shifted from free play and mobility towards various adult-led organised activities and why parents deem it necessary to control children’s leisure journeys in an unprecedented manner. Most of the research on parenting and mobility has explained these trends with urban risks and safeguarding, but this paper highlights how parents also control, manage and enable children’s mobility to resource and enrich them with various dispositions. We use children’s mobility exper…
Effects of initial performance, gross efficiency and VO_2peak characteristics on subsequent adaptations to endurance training in competitive cyclists
2018
The present study investigated the effects of initial levels of cycling performance, peak oxygen uptake (www.frontiersin.orgO2peak) and gross efficiency (GE) on the subsequent adaptations of these variables and their relationship following high-intensity training (HIT) designed to increase www.frontiersin.orgO2peak in competitive cyclists. Sixty cyclists (www.frontiersin.orgO2peak = 61 ± 6 mL kg-1 min-1) were assigned a 12-week training program consisting of twenty-four supervised high-intensity interval training sessions and ad libitum low intensity training. GE was calculated at 125, 175, and 225 W and performance was determined by mean power during a 40-min time-trial (Power40 min). In a…
Effects of Initial Performance, Gross Efficiency and O
2017
The present study investigated the effects of initial levels of cycling performance, peak oxygen uptake (O2peak) and gross efficiency (GE) on the subsequent adaptations of these variables and their relationship following high-intensity training (HIT) designed to increase O2peak in competitive cyclists. Sixty cyclists (O2peak = 61 ± 6 mL kg-1 min-1) were assigned a 12-week training program consisting of twenty-four supervised high-intensity interval training sessions and ad libitum low intensity training. GE was calculated at 125, 175, and 225 W and performance was determined by mean power during a 40-min time-trial (Power40 min). In addition to correlation analyses between initial level and…
Mean speed in professional cycling: No evidence of decline
2014
Abstract The aim of this article was to evaluate the mean speed progression of the three major cycling stage races in order to empirically establish whether excellent in performance in professional cycling is to some extent correlated with the trend of blood doping and anti-doping throughout more than a century of official cycling competitions. We retrieved data about the mean speed of the winners of the Tour de France, Giro d’Italia and Vuelta a Espana, since their beginning. A linear correlation has then been calculated between the years and the mean speed in km/h for each single major cycling stage race, as well as for the mean speed of the winners of the three major cycling stage races …
Analysis of ultra-triathlon performances
2011
Romuald Lepers1, Beat Knechtle2,3, Patrizia Knechtle2, Thomas Rosemann2 1INSERM U887, Faculty of Sport Sciences, University of Burgundy, Dijon, France; 2Institute of General Practice and Health Services Research, University of Zurich, Switzerland; 3Gesundheitszentrum St Gallen, St Gallen, Switzerland Abstract: Despite increased interest in ultra-endurance events, little research has examined ultra-triathlon performance. The aims of this study were: (i) to compare swimming, cycling, running, and overall performances in three ultra-distance triathlons, double Ironman distance triathlon (2IMT) (7.6 km swimming, 360 km cycling, and 84.4 km running), triple Ironman distance triathlon (3IMT) (11.…
Towards sustainable mobility : Transformative scenarios for 2034
2022
Highlights • Increasing the share of walking and cycling is one of the building blocks of sustainable mobility transformation. • We organised an online Delphi survey for 30 walking and cycling experts during the first wave of COVID-19 pandemic. • Disaggregative Delphi analysis is elaborated based on the systemic restructuring of qualitative data. • Transport experts’ views of the future are described in the form of five walking and cycling scenarios up to 2034. • The results can be used for strategic transport planning and policy, and for identifying instruments for walking and cycling promotion in urban areas. Increasing the share of walking and cycling is one of the building blocks of sus…
Extended valence theory perspective on consumers' e-waste recycling intentions in Japan
2021
The gravity of the electronic waste (e-waste) crisis can be attributed to consumers' low participation in ensuring the proper disposal of such materials. Motivating consumers to recycle e-waste requires a deeper understanding of the dimensions that underlie behavioral intentions. Accordingly, the present study uses the novel framework of Valence Theory (VT) to examine how consumers evaluate their decision to recycle e-waste. The authors propose an extended VT model incorporating consumer values (value compatibility, openness to change, and environmental concerns), which is validated using cross-sectional survey data from 774 Japanese consumers. We also examine the role of different moderato…
Moving forward sustainably : material and social conditions of electronic waste management in Nigeria
2018
This dissertation focuses on understanding the social material interaction between e-waste and e-scrappers for sustainable management of e-waste. Previous studies mainly concentrate on the detrimental environmental impact of e-scrappers activities, the economic and political influences of e-waste on the e-scrappers, the material flow of e-waste and the exportation of valuable e-waste extracts from highly industrialized countries to less industrialized countries. The aim of the dissertation is therefore to extend the scope of the previous studies by investigating the social material interaction between e-scrappers and e-waste. To achieve this aim, this study examines the following research q…
Can cycling with an E-bike improve fitness? : effect of access to an Electric Assisted Bicycle on cycling distance and cardiopulmonary fitness in ina…
2016
Masteroppgave folkehelsevitenskap - Universitetet i Agder 2016 Background: The aims of the present study were to assess the effect of an eight-month intervention with access to an Electric assisted bicycle (E-bike) on (1) the amount of E-biking, (2) changes in cardiopulmonary fitness and (3) to assess whether cycled distance was associated with changes in cardiopulmonary fitness, among inactive adults. Methods: Twenty-five inactive Norwegian adults (33 – 57 years of age, 72 % women), were recruited through convenience sampling. Participants were given an E-bike for eight (N = 23) or three (N = 2) months. Socio-demographic characteristics were reported with a questionnaire. Bicycle use was m…
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome
2014
Activating mutations in genes encoding phosphatidylinositol 3-kinase (PI3K)-AKT pathway components cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH, OMIM 603387)(1-3). Here we report that individuals with MPPH lacking upstream PI3K-AKT pathway mutations carry de novo mutations in CCND2 (encoding cyclin D2) that are clustered around a residue that can be phosphorylated by glycogen synthase kinase 313 (GSK-3 beta)(4). Mutant CCND2 was resistant to proteasomal degradation in vitro compared to wild-type CCND2. The PI3K-AKT pathway modulates GSK-3 beta activity(4), and cells from individuals with PIK3CA, PIK3R2 or AKT3 mutations showed similar CCND2 accumulation. CCND…