Search results for "Cyst"

showing 10 items of 1960 documents

Kidney donors and kidney transplants have abnormal aminothiol redox status, and are at increased risk of oxidative stress and reduced redox buffer ca…

2013

Abstract Objective Living kidney donors have been part of a successful kidney transplant programme in Norway for almost 50 years. Glomerular filtration rates (GFRs) have tended to remain stable at about 70% of pre-donation levels. Plasma total homocysteine (Hcy) has an inverse relationship to kidney function, and previous reports indicate elevated levels of Hcy in kidney donors. We wanted to examine the most important plasma aminothiols in kidney donors, i.e. Hcy, cysteine (Cys) and cysteinylglycine (CG) with their redox species. The aminothiol redox-system appears to be an integral part of the extracellular antioxidant defence system in the body. Design and methods Plasma concentrations of…

Malemedicine.medical_specialtyAntioxidantHomocysteinemedicine.medical_treatmentClinical BiochemistryRenal functionBuffersmedicine.disease_causeRedoxPreeclampsiachemistry.chemical_compoundRisk FactorsInternal medicineLiving DonorsmedicineExtracellularHumansCysteineSulfhydryl CompoundsHomocysteineDemographyKidneyurogenital systemDipeptidesGeneral MedicineMiddle Agedmedicine.diseaseKidney TransplantationOxidative StressEndocrinologymedicine.anatomical_structurechemistryCase-Control StudiesFemaleOxidation-ReductionOxidative stressClinical Biochemistry
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The management of abdominal hydatidosis after the rupture of a pancreatic hydatid cyst: a case report

2015

Introduction Echinococcosis or hydatidosis is a zoonosis caused by cestodes from the genus Echinococcus; its habitat is the small intestine of the definitive host, represented by dogs/carnivorous animals, where it produces eggs which are eliminated in the environment. Cystic echinococcosis represents more than 95% of the hydatidosis cases registered annually. The most frequent localization is the hepatic one, followed by the pulmonary localization with a ratio of 2.5:1. A pancreatic localization represents 0.2% of hydatidosis cases with a higher possibility of disseminating intra-abdominally. The incidence of hydatidosis in Romania has not been investigated yet through national studies. Cas…

Malemedicine.medical_specialtyCase ReportAlbendazoleAlbendazoleEchinococcosisSurgical oncologyAnimalsHumansMedicineAnti-parasite treatmentAnthelminticsEchinococcus genusMedicine(all)Rupture SpontaneousRomaniabusiness.industryIncidence (epidemiology)ZoonosisPancreatic DiseasesPancreatic cystGeneral MedicineMiddle Agedmedicine.diseaseEchinococcosisSurgeryPraziquantelAcute abdomenIntraabdominal InfectionsAcute pancreatitismedicine.symptombusinessmedicine.drugJournal of Medical Case Reports
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Multiple intrahepatic pseudocysts in acute pancreatitis

2007

Liver pseudocysts are a very rare complication in acute pancreatitis with only a few cases previously described. The lack of experience and literature on this condition leads to difficulties in the differential diagnosis and management. We report herein a case of acute pancreatitis who developed multiple intrahepatic pseudocysts. After complete imaging evaluation, the diagnosis was still unclear and the patient was operated on. The presence of liver lesions in patients with acute pancreatitis should raise the possibility of intrahepatic pseudocysts.

Malemedicine.medical_specialtyCase ReportSeverity of Illness IndexGastroenterologyDiagnosis DifferentialInternal medicineSeverity of illnessmedicineHumansIn patientAgedmedicine.diagnostic_testCystsbusiness.industryLiver DiseasesGastroenterologyMagnetic resonance imagingGeneral Medicinemedicine.diseaseMagnetic Resonance Imagingdigestive system diseasesTreatment OutcomeTomography x ray computedPancreatitisAcute DiseasePancreatitisAcute pancreatitisDifferential diagnosisTomography X-Ray ComputedbusinessComplicationWorld Journal of Gastroenterology
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Ursodeoxycholic acid protects against secondary biliary cirrhosis in rats by preventing mitochondrial oxidative stress

2004

Ursodeoxycholic acid (UDCA) improves clinical and biochemical indices in primary biliary cirrhosis and prolongs survival free of liver transplantation. Recently, it was suggested that the cytoprotective mechanisms of UDCA may be mediated by protection against oxidative stress, which is involved in the development of cirrhosis induced by chronic cholestasis. The aims of the current study were 1) to identify the mechanisms involved in glutathione depletion, oxidative stress, and mitochondrial impairment during biliary cirrhosis induced by chronic cholestasis in rats; and 2) to determine the mechanisms associated with the protective effects of UDCA against secondary biliary cirrhosis. The find…

Malemedicine.medical_specialtyCirrhosisCardiolipinsGlutamate-Cysteine LigaseBiliary cirrhosisPopulationBiologymedicine.disease_causeMembrane Potentialschemistry.chemical_compoundPrimary biliary cirrhosisInternal medicinemedicineCardiolipinAnimalsRats Wistareducationeducation.field_of_studyCholestasisHepatologyLiver Cirrhosis BiliaryUrsodeoxycholic AcidCystathionine gamma-LyaseGlutathionemedicine.diseaseGlutathioneUrsodeoxycholic acidMitochondriaPeroxidesRatsOxidative StressEndocrinologyLiverchemistryChronic DiseaseHepatocytesOxidation-ReductionOxidative stressmedicine.drugHepatology
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Case report: Trans-papillary free stenting of the cystic duct and of the common bile duct in a double biliary ducts anastomoses of a right lobe livin…

2021

Abstract Background One of the major issues related to the living donor liver transplantation recipient outcome is still the high rate of biliary complication, especially when multiple biliary ducts are present and multiple anastomoses have to be performed. Case presentation and conclusion We report a case of adult-to-adult right lobe living donor liver transplantation performed for a recipient affected by alcohol-related cirrhosis with MELD score of 17. End-stage liver disease was complicated by refractory ascites, portal hypertension, small esophageal varices and portal gastropathy, hypersplenism, and abundant right pleural effusion. Here in the attached video we described the adult-to-ad…

Malemedicine.medical_specialtyCirrhosismedicine.medical_treatmentBiliary anastomoseslcsh:SurgeryAnastomosisLiver transplantationEsophageal varicesCholestasisLiver Cirrhosis AlcoholicmedicineLiving DonorsHumansCommon Bile DuctCommon bile ductbusiness.industryLiving donor liver transplantationAnastomosis SurgicalCystic Ductlcsh:RD1-811General MedicineMiddle Agedmedicine.diseaseSurgeryLiver TransplantationTransplantationmedicine.anatomical_structureTreatment OutcomeCystic ductSurgeryStentsBile DuctsbusinessResearch ArticleBMC surgery
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Postoperative complications and 90-day mortality in radical cystectomy in high-risk patients: A monocentric retrospective observational study.

2018

Aim: Assessing the incidence of immediate postoperative complications and 90-day mortality in high-risk patients who have undergone radical cystectomy; evaluating the correlation between preoperative conditions and surgery outcomes. Materials and methods: This is a monocentric retrospective observational study in which data of 65 patients have been analyzed. High-risk criteria: (a) Age ≥75 years, (b) obesity, (c) age-adjusted Charlson Comorbidity Index ≥8, (d) anemic status, and (e) pT ≥3. More than 50% of patients had two or more “high-risk” indicators. Postoperative complications were assessed through Clavien–Dindo classification. Results: Average age of patients was 70.4 years, average a…

Malemedicine.medical_specialtyClavien-Dindo ClassificationTime Factorsmedicine.medical_treatment030232 urology & nephrologyCystectomyRisk AssessmentSettore MED/24 - UrologiaCystectomy03 medical and health sciences0302 clinical medicinePostoperative ComplicationsmedicineHumansRisk factorAgedRetrospective Studiesbusiness.industryMortality rateIncidence (epidemiology)Retrospective cohort studyGeneral MedicineOdds ratioMiddle AgedSurgeryUrinary Bladder Neoplasms030220 oncology & carcinogenesisRadical cystectomy bladder cancer Clavien–Dindo classification complications and mortalityFemalebusinessBody mass indexUrologia
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Alzheimer's disease: amino acid levels and brain metabolic status.

2013

Abstract To study brain free amino acids and their relation with dementia we measured, by high-performance liquid chromatography (HPLC), the concentration of eight free amino acids, amines and related compounds. We used temporal cortex (TC) samples obtained from 13 Alzheimer’s disease (AD) patients and an equal number of agematched controls (AC). The patterns of free amino acids, amines and related compounds showed significant quantitative changes in AD conditions with respect to healthy ones. In Alzheimer patients, lower levels of GABA were found in the TC (-57 %). Amino acids glutamate (Glu), and aspartate (Asp) concentrations, also appeared significantly reduced in the TC of AD patients …

Malemedicine.medical_specialtyDermatologyBiologychemistry.chemical_compoundBrain: Temporal cortexAlzheimer DiseaseSettore BIO/10 - BiochimicaInternal medicinemedicineHumansNeurotransmitterAmino AcidsChromatography High Pressure Liquidgamma-Aminobutyric AcidAgedTemporal cortexchemistry.chemical_classificationMethionineGlutamate receptorBrainGeneral Medicinemedicine.diseaseCystathionine beta synthaseAmino acidAmino acidGlutaminePsychiatry and Mental healthEndocrinologychemistryBiochemistryTemporal cortex; Amino acids; Neurotransmitters; [Keywords Alzheimer’s disease; Brain]biology.proteinFemaleKeywords Alzheimer’s diseaseNeurology (clinical)Alzheimer's diseaseTransmethylationNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
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Type 2 diabetes mellitus predicts worse outcomes in patients with high-grade T1 bladder cancer receiving bacillus Calmette-Guérin after transurethral…

2020

Objectives: The aim of this multicenter study was to investigate the prognostic role of type 2 diabetes mellitus (T2DM) comorbidity in a large multi-institutional cohort of patients with primary T1HG/G3 non–muscle-invasive bladder cancer (NMIBC) treated with transurethral resection of the bladder (TURB). Materials and methods: A total of 1,172 patients with primary T1 HG/G3 who had NMIBC on re-TURB and who received adjuvant intravesical bacillus Calmette-Guérin therapy with maintenance were included. Endpoints were recurrence-free survival and progression-free survival. Results: A total of 231 (19.7%) of patients had T2DM prior to TURB. Five-year recurrence-free survival estimates were 12.5…

Malemedicine.medical_specialtyDiabetes mellituUrologymedicine.medical_treatment030232 urology & nephrologyUrologyCystectomyResection03 medical and health sciences0302 clinical medicineDiabetes mellitusHigh gradeAdjuvants ImmunologicUrethraRecurrenceDiabetes mellitusmedicineHumansIn patientNeoplasm InvasivenessAgedNeoplasm StagingRetrospective StudiesBladder cancerProgressionbusiness.industryHigh riskBladder cancerType 2 Diabetes MellitusMiddle Agedmedicine.diseasePrognosisComorbidityProgression-Free Survival3. Good healthBladder cancer; Diabetes mellitus; High grade; High risk; Progression; RecurrenceSettore MED/24OncologyDiabetes Mellitus Type 2Urinary Bladder NeoplasmsChemotherapy Adjuvant030220 oncology & carcinogenesisCohortBCG VaccineFemaleNeoplasm GradingbusinessAdjuvantUrologic oncology
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Giant hepatic hydatid cyst as a cause of small bowel obstruction.

2006

Today, giant hydatid cysts are fairly rare even in endemic areas. We describe a case of an extremely large hydatid cyst of the liver that was causing massive compression of the neighboring organs, giving rise to a subocclusive syndrome of the intestine. After considering the various approaches available for the treatment of this disease, it was decided that radical surgery was still the best therapeutic choice, especially when extremely large cysts are involved. In particular, in clinical situations where it is difficult to perform radical surgical procedures, less aggressive surgery followed by drug treatment should be the treatment of choice.

Malemedicine.medical_specialtyEchinococcosis Hepaticalanine aminotransferase aspartate aminotransferase contrast mediumoral contraceptive agentHelminthiasisAntiprotozoal AgentsHydatid cystHepatic ComplicationAlbendazoleAggressive surgeryDrug treatmentparasitic diseasesIntestine SmallmedicineHumansRadical surgeryAgedbusiness.industryGeneral Medicinemedicine.diseaseEchinococcosisSurgeryBowel obstructionSettore MED/18 - Chirurgia GeneraleDrug Therapy CombinationbusinessTomography X-Ray ComputedIntestinal Obstruction
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Lumbar osteomyelitis and epidural abscess complicating recurrent pilonidal cyst: report of a case.

2000

PURPOSE: This study was conducted to report the rare presentation of lumbar osteomyelitis and epidural abscess as a complication of a pilonidal cyst. METHODS: A case report is presented. RESULTS: We describe the rare case of a male patient with diabetes with a recurring pilonidal cyst who developed a lumbar osteomyelitis and epidural abscess three weeks after pilonidal cyst excision with epidural anesthesia, with a fatal outcome despite emergency treatment. CONCLUSIONS: Life-threatening complications should be kept in mind in high-risk patients with repetitive surgery and neurologic involvement.

Malemedicine.medical_specialtyEpidural abscessLumbar vertebraeLumbarFatal OutcomePilonidal SinusRecurrencemedicineHumansAbscessPilonidal cystLumbar Vertebraebusiness.industryOsteomyelitisGastroenterologyOsteomyelitisGeneral MedicineMiddle Agedmedicine.diseaseMagnetic Resonance ImagingSurgerymedicine.anatomical_structureEpidural AbscessOsteitisbusinessComplicationDiseases of the colon and rectum
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