Search results for "Cyst"

showing 10 items of 1960 documents

Smoking habits of parents and male: female ratio in spermatozoa and preimplantation embryos

2005

BACKGROUND Previous observations have addressed a decreased male:female ratio associated with smoking. Our aim was to assess whether this effect is observed at the spermatozoa or at the early embryo development. METHODS We retrospectively assessed smoking intake habits of 56 couples included in our preimplantation genetic diagnosis (PGD) program. Three groups were established according to male or female cigarette consumption per day: non-smokers, smokers (1-19 cigarettes per day) and heavy smokers (> or =20 cigarettes per day). Fluorescence in-situ hybridization (FISH) was performed on ejaculated sperm samples to analyse chromosomes X and Y. On day 3, embryos were also analysed. Additionall…

AdultMaleSemenBiologyPreimplantation genetic diagnosisAndrologyPregnancyCapacitationmedicineHumansSex RatioIn Situ Hybridization FluorescenceRetrospective StudiesChromosomes Human XChromosomes Human Ymedicine.diagnostic_testIncidenceIncidence (epidemiology)SmokingRehabilitationObstetrics and GynecologyEmbryoSpermatozoaSpermBlastocystReproductive MedicineFemaleSex ratioFluorescence in situ hybridizationHuman Reproduction
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Diagnostic accuracy of fecal elastase 1 assay in patients with pancreatic maldigestion or intestinal malabsorption: a collaborative study of the Ital…

2001

Several reports have indicated that fecal elastase-1 (EL-1) determination is a new, sensitive, and specific noninvasive pancreatic function test; however, very few patients with malabsorption due to small intestine diseases have been included in the previous studies. The aim of the study was to compare the diagnostic accuracy of fecal EL-1 and fecal chymotrypsin (FCT) in distinguishing between pancreatic maldigestion and intestinal malabsorption. Three groups of subjects were studied: group A included 49 patients with known cystic fibrosis (25 males, median age 5 years); group B included 43 subjects with various small intestine diseases (17 males, median age 6 years); and group C included 4…

AdultMaleSettore MED/09 - Medicina InternaAdolescentCystic FibrosisIntestinal giardiasiFecesSensitivityMalabsorption Syndromesspecificity; pancreatic insufficiency; sensitivity; malabsorption syndrome; intestinal giardiasis; cystic fibrosis; steatorrhea; fecal elastase-1: fecal chymotrypsin; celiac diseaseMalabsorption syndromeCeliac diseaseHumansintestinal giardiasisChildPancreatic ElastaseGastroenterologyInfant NewbornInfantPancreatic DiseasesReproducibility of ResultsClinical Enzyme TestsSteatorrheaIntestinal DiseasesCystic fibrosiChild PreschoolSpecificityFecal elastase-1: fecal chymotrypsinDigestionFemalePancreatic insufficiencyDigestive diseases and sciences
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Adaptation to life after surgical removal of the bladder—an application of graphical Markov models for analysing longitudinal data

2004

Graphical Markov models have been developed particularly for the analysis of observational data. They allow the control of various background variables when analysing theoretically relevant associations. This paper demonstrates the application and some advantages of graphical Markov models in comparison to conventional statistical analyses. The aim of the study was to identify patients at risk for developing decreased health-related quality of life (QoL) after cystectomy and to explore the influence of coping on QoL in this situation. Therefore, the method was applied to analyse the data of a prospective study, in which 81 patients with bladder cancer were interviewed pre-operatively and in…

AdultMaleStatistics and ProbabilityLongitudinal studyCoping (psychology)Operations researchEpidemiologyLongitudinal datamedicine.medical_treatmentMarkov modelCystectomySurgical removalAdaptation PsychologicalmedicineHumansLongitudinal StudiesProspective cohort studyMiddle AgedMarkov ChainshumanitiesUrinary Bladder NeoplasmsResearch DesignQuality of LifeFemaleObservational studyPsychologyClinical psychologyStatistics in Medicine
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Serum amino acid concentrations in aging men and women.

2003

The age and gender related differences in serum amino acid concentrations have been assessed in 72 (23-92 years) medically screened healthy men and women who were divided into three male and three female groups according to age. Free-time physical activity and food intake were analysed from the 5-day diaries. The subjects were instructed to eat according to their normal dietary habits and to avoid any clinical complementary nutritional products or other products that could increase protein or energy intake. The blood samples (5 ml) taken from the antecubital vein after an over-night fast were analysed for their amino acid contents by chromatography. In total nutrient intake of energy (P < 0…

AdultMaleTaurinemedicine.medical_specialtyAgingClinical BiochemistryAlcoholBiochemistrySerinechemistry.chemical_compoundInternal medicineCitrullinemedicineHumansAmino AcidsEssential amino acidAgedchemistry.chemical_classificationAged 80 and overSex CharacteristicsOrganic ChemistryMiddle AgedAmino acidEndocrinologychemistryBiochemistryGlycineFemaleCysteineAmino acids
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Analysis of genetic variations of protein tyrosine kinase fyn and their association with alcohol dependence in two independent cohorts.

2003

Abstract Background Decreased sensitivity to and increased tolerance for the effects of alcohol is a phenotype, which was shown to be associated with an increased risk for alcoholism in humans and was observed in protein tyrosine kinase (PTK) fyn knockout mice. Methods We performed an association study of genetic variations of PTK fyn in 430 alcohol-dependent patients and 365 unrelated control subjects from two independent samples. Results In a combined analysis, we found an association of alcohol dependence with the single nucleotide polymorphism (SNP) T137346C in the 5′ untranslated region (UTR) of the gene. A relevant association could be excluded for the remaining two informative SNPs. …

AdultMaleThreonineLinkage disequilibriumGenotypeGlycineSingle-nucleotide polymorphismBiologyProto-Oncogene Proteins c-fynPolymorphism Single NucleotideCohort StudiesFYNGene FrequencyProto-Oncogene ProteinsGenotypeSNPHumansCysteineAlleleBiological PsychiatryGeneticsAlanineChi-Square DistributionAlcohol dependenceGenetic VariationMiddle AgedAlcoholismCase-Control StudiesFemale5' Untranslated RegionsTyrosine kinaseBiological psychiatry
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Prognostic significance of DNA ploidy, S-phase fraction, and tissue levels of aspartic, cysteine, and serine proteases in operable gastric carcinoma

2000

A consecutive series of 63 untreated patients undergoing surgical resection for stage I-IV gastric adenocarcinomas (GCs) has been prospectively studied. Our purpose was to analyze the predictive relevance of DNA ploidy, S-phase fraction (SPF), and tissue levels of lysosomal proteinases cathepsin D (CD), cathepsin B (CB), cathepsin L (CL), and urokinase-type plasminogen activator (uPA) and that of the intracellular cysteine proteinase inhibitor stefin A on clinical outcome. All of the patients taking part in this study were followed up for a median of 73 months. DNA aneuploidy was present in 71% of the cases (45/63), whereas 9% of these (4/45) showed multiclonality. Both DNA ploidy and SPF w…

AdultMaleTime FactorsAdenocarcinomaS PhasePredictive Value of TestsStomach NeoplasmsBiomarkers TumorAspartic Acid EndopeptidasesHumansNeoplasm Invasivenesshumancell cycle S phase; disease association; female; histopathology; human; lymph node metastasisAgedProbabilityPloidieslymph node metastasisdisease associationSerine EndopeptidasesDNA NeoplasmMiddle AgedPrognosisSurvival AnalysisCysteine Endopeptidasescell cycle S phaseLymphatic MetastasishistopathologyFemaleFollow-Up Studies
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Odontogenic cysts: Demographic profile in a Brazilian population over a 38-year period

2009

Objective: To determine the distribution of odontogenic cysts diagnosed histologically over a period of 38 years in a Brazilian population according to age, gender and site affected and to compare these data with previously reported studies from other countries. Study design: A total of 1019 cases of odontogenic cysts diagnosed between 1970 and 2007 were studied. Clinical features obtained from the patient records and microscope slides were reviewed according to the 1992 World Health Organization classification. Results: The mean age was 31.0 years, and there was a predominance of females. The most frequent odontogenic cysts were radicular cysts (61.4%), followed by dentigerous cysts (20.1%…

AdultMaleTime FactorsAdolescentDentistryYoung AdultOdontogenic cystparasitic diseasesHumansMedicineMandibular DiseasesMaxillary central incisorChildGeneral DentistryAgedAged 80 and overRadicular Cystbusiness.industryIncidence (epidemiology)Infant NewbornMandibleInfantMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseMaxillary DiseasesOdontogenicstomatognathic diseasesOtorhinolaryngologyChild PreschoolMaxillaUNESCO::CIENCIAS MÉDICASOdontogenic CystsFemaleSurgeryBrazilian populationbusinessBrazilMedicina Oral Patología Oral y Cirugia Bucal
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Economic aspects of different muscle relaxant regimens.

2000

Objective At a time of cost reduction in medical care efforts to manage the ever-increasing costs of new pharmaceutical drugs become increasingly important. Costs of four different muscle relaxant regimens including the new intermediate-acting neuromuscular blocking drugs (NMBD) cisatracurium and rocuronium will be analyzed. Methods Eighty patients undergoing laparoscopic cholecystectomy were prospectively studied. All patients received standardized general anaesthesia with desflurane/fentanyl. Muscle relaxation was achieved with atracurium, cisatracurium, vecuronium, or rocuronium with 20 patients in each group. Intraoperatively muscle relaxants were added to maintain two twitches of the t…

AdultMaleTime Factorsmedicine.drug_classCritical Care and Intensive Care MedicineDrug CostsPacuFentanylDesfluraneIntraoperative PeriodMedicineHumansGeneral anaesthesiaAnesthesiaAndrostanolsProspective StudiesRocuroniumAgedAged 80 and overPostoperative CareNeuromuscular BlockadeVecuronium Bromidebiologybusiness.industryMuscle Relaxants CentralMuscle relaxantGeneral MedicineMiddle Agedbiology.organism_classificationAnesthesiology and Pain MedicineMuscle relaxationTreatment OutcomeCholecystectomy LaparoscopicAnesthesiaEmergency MedicineAtracuriumFemaleRocuroniumbusinessmedicine.drugNeuromuscular Nondepolarizing AgentsAnasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
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Neoplasms of the salivary glands in a Turkish adult population

2009

WOS: 000284036700011

AdultMaleTurkish populationPathologymedicine.medical_specialtyAdolescentTurkeyAdenoid cystic carcinomaTurkishTurkishneoplasmsBenign tumorPleomorphic adenomaYoung AdultHumansMedicineNeoplasmGeneral DentistryAgedRetrospective StudiesSalivary glandSalivary glandbusiness.industryRetrospective cohort studyMiddle AgedSalivary Gland Neoplasms:CIENCIAS MÉDICAS [UNESCO]medicine.diseaselanguage.human_languagemedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASlanguageFemaleSurgerybusiness
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Endoscopic Procedures through the Foramen Interventriculare of Monro under Stereotactical Conditions

1994

The foramen interventriculare of Monro is an anatomical narrowness for the endoscopic access to the third ventricle. The effective mechanical angle to pass the foramen interventriculare from a frontal bore hole depends on the diameter in the plane of entrance, the depth of the foramen, and the diameter of the endoscope. Under the pathological conditions of a hydrocephalus internus the foramen interventriculare is enlarged. By means of stereotactical guidance, it is possible to reach the third ventricle accurately without damaging anatomical structures around the foramen interventriculare. The endoscopic technique under stereotactical guidance using a rigid endoscope is sufficient and safe t…

AdultMaleVentriculostomymedicine.medical_specialtyAdolescentEndoscopeBiopsymedicine.medical_treatmentPerforation (oil well)Constriction PathologicAstrocytomaCerebral VentriclesVentriculostomyStereotaxic Techniquesstomatognathic systemmedicineForamenHumansChildAgedEndoscopesBrain DiseasesThird ventricleColloid cystmedicine.diagnostic_testBrain NeoplasmsCystsbusiness.industryEndoscopyEquipment DesignGeneral MedicineMiddle Agedmedicine.diseaseHydrocephalusEndoscopybody regionsmedicine.anatomical_structureChild Preschoolcardiovascular systemFemaleSurgeryNeurology (clinical)RadiologyEmergenciesbusinessmin - Minimally Invasive Neurosurgery
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