Search results for "Cyst"

showing 10 items of 1960 documents

Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group

2011

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females, with a high prevalence. The etiology of this heterogeneous condition remains obscure, and its phenotype expression varies. Two widely cited previous ESHRE/ASRMsponsored PCOS consensus workshops focused on diagnosis (published in 2004) and infertility management (published in 2008), respectively. The present third PCOS consensus report summarizes current knowledge and identifies knowledge gaps regarding various women's health aspects of PCOS. Relevant topics addressed-all dealt with in a systematic fashion-include adolescence, hirsutism and acne, contraception, menstrual cycle abnormalities, quality of life, e…

Infertilitymedicine.medical_specialtyConsensusMEDLINEmetabolic syndromeSettore MED/13 - EndocrinologiaPolycystic Ovary Syndrome Adolescence Metabolism Cardiovascular riskMetabolic DiseasesQuality of lifeSDG 3 - Good Health and Well-beingPregnancyRisk Factorscardiovascular diseaseNeoplasmsinsulin resistancemedicineHumanscancerPolycystic ovary syndromehirsutismhirsutismGynecologybiologypregnancy complicationsbusiness.industryPolycystic ovary syndrome (PCOS)cancer; cardiovascular disease; contraception; hirsutism; insulin resistance; metabolic syndrome; Polycystic ovary syndrome; pregnancy complications; quality of life; type 2 diabetesObstetrics and GynecologyAnti-Müllerian hormonemedicine.diseasePolycystic ovarycontraceptionquality of lifeReproductive MedicineCardiovascular DiseasesFamily medicinebiology.proteinEtiologyFemaletype 2 diabetesbusinessInfertility Female
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Deficiencies in reporting results of lesbians and gays after donor intrauterine insemination and assisted reproductive technology treatments: a revie…

2015

At a time when increasing numbers of lesbians and gays consider parenthood using reproductive assistance in infertility centers, the present review aims to summarize the results obtained so far by lesbians after intrauterine insemination (IUI) and in-vitro fertilization (IVF) using donor spermatozoa (D-IUI and D-IVF, respectively) and gays entering into gestational-surrogacy programs. Data show that gays display normal semen parameters and lesbians exhibit no specific causes of female infertility except perhaps for polycystic ovary syndrome (PCOS) and some PCOS-related factors. Pair-bonded lesbians entering into D-IUI programs, tend to have higher pregnancy and delivery percentages followin…

Infertilitymedicine.medical_specialtyGestational surrogacyPregnancy RateReproductive Techniques AssistedCause of infertilitySexual Behaviormedia_common.quotation_subjectmedicine.medical_treatmentReproductive medicineFertilityReviewIn-vitro fertilizationMiscarriageEndocrinologyPregnancymedicineHumansreproductive and urinary physiologySurrogate Mothersmedia_commonDonor intrauterine inseminationPregnancyAssisted reproductive technologyObstetricsbusiness.industryFemale infertilityObstetrics and Gynecologymedicine.diseasePolycystic ovaryReproductive MedicineInfertilitybehavior and behavior mechanismsSexual orientationInsemination Artificial HeterologousOocyte-donation cyclesFemaleSemen parametersbusinessDevelopmental BiologyReproductive Biology and Endocrinology
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Reproductive System Outcome Among Patients with Polycystic Ovarian Syndrome.

2015

Polycystic ovarian syndrome (PCOS) may present with different clinical patterns and the anovulatory phenotype may not be the most common. Data suggest that anovulation in PCOS is not the consequence of increased androgen ovarian secretion but rather of a severe derangement of early follicle development. Other mechanisms may be operative in subgroups of patients and may contribute to the arrest of follicle growth and anovulation. At least 50% of anovulatory patients with PCOS become ovulatory in their late reproductive age. There is also evidence that menopause may occur later in women with PCOS. Finally, a strategy for treatment of infertility in PCOS is presented.

Infertilitymedicine.medical_specialtyendocrine system diseasesmedicine.drug_classEndocrinology Diabetes and MetabolismAnovulationFollicleEndocrinologyInsulin resistancemedicineHumansGynecologybusiness.industryFemale infertilityHyperandrogenismnutritional and metabolic diseasesmedicine.diseaseAndrogenfemale genital diseases and pregnancy complicationsMenopauseFertilityFemaleMenopausebusinessInfertility FemaleAnovulationPolycystic Ovary SyndromeEndocrinology and metabolism clinics of North America
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Association of redox and inflammation-related biomarkers with prognosis in IgA nephropathy: A prospective observational study.

2022

IgA nephropathy (IGAN) has a variable prognosis. Risk stratification tools are usually based on clinical parameters combined with histologic Oxford-MEST-C score. Circulating redox- and inflammation-related biomarkers may be related to histological changes in IGAN. Therefore, we studied the performance of these biomarkers in predicting the rate of GFR-loss in IGAN.This was an observational prospective study. Fifty-seven stable patients with IGAN were examined at baseline and after a mean observational time of 5.9 ± 1.1 years. The main outcome measure was eGFR-loss per year with predefined groups, stable (1.5 ml/min/1,73 mFifteen patients were in the progressive, 11 in the intermediate, and 3…

InflammationGlomerulonephritis IGABiochemistryAdvanced Oxidation Protein ProductsReceptors Tumor Necrosis Factor Type IPhysiology (medical)Disease ProgressionHumansVDP::Medisinske Fag: 700OsteopontinCysteineProspective StudiesOxidation-ReductionBiomarkersGlomerular Filtration RateFree radical biologymedicine
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Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation.

2015

Novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation were developed; some of them possess K(i) values in the micromolar range. We studied the structure-activity relationship of these derivatives and we performed docking studies, which allowed us to find out the key interactions established by the inhibitors with the target enzyme. Biological results indicate that the nature of the P2 and P3 substituents and their binding to the S2/S3 pockets is strictly interdependent.

InhibitorMolecular modelCell SurvivalClinical BiochemistryTrypanosoma brucei bruceiAntiprotozoal AgentsPharmaceutical ScienceMolecular modelingCysteine Proteinase InhibitorsBiochemistryCell Linechemistry.chemical_compoundMiceStructure-Activity RelationshipCysteine ProteasesDrug DiscoveryAnimalsMolecular Biology3-Bromo isoxazolinechemistry.chemical_classificationDipeptide-likeDipeptideBinding SitesOrganic ChemistryDipeptidesIsoxazolesCombinatorial chemistryProtein Structure TertiaryMolecular Docking SimulationCysteine EndopeptidasesEnzymeRhodesainchemistryWarheadDocking (molecular)Drug DesignMolecular MedicineRhodesain Dipeptide-like 3-Bromo isoxazoline Inhibitor Molecular modelingBioorganicmedicinal chemistry
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Arsenic, antimony and bismuth complexation by L-cysteine in water

1984

Synthese, dans l'eau, des complexes L-cysteine: AsL 3 , SbL 3 •H 2 O et BiL 3 .H 2 O L=forme monoanionique de cysteine. Etude IR des structures

Inorganic ChemistrychemistryAntimonyInfraredInorganic chemistryMaterials Chemistrychemistry.chemical_elementMoleculePhysical and Theoretical ChemistryHydrateArsenicBismuthCysteineInorganica Chimica Acta
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Hypsipyrgias joseliae, a new species of lace bugs (Heteroptera: Tingidae: Tinginae) from New Guinea with a key to species of the genus Hypsipyrgias, …

2021

Hypsipyrgias joseliae sp. n. (Heteroptera: Tingidae: Tinginae) from New Guinea is described, illustrated and compared with its two relatives, namely H. telamonides Kirkaldy, 1908 from Australia, and H. euphues Drake and Ruhoff, 1962 from Lord Howe Island. Key to species of the genus Hypsipyrgias is also provided. Two genera very closely related to Hypsipyrgias Kirkaldy, 1908, namely Hypsotingis Drake, 1960 and Diplocysta Horváth, 1925 are re-diagnosed. Diplocysta globuliformis Hacker, 1928, D. papuana Drake, 1960, D. rustica, Drake, 1960 and D. thaleia Drake and Ruhoff, 1965 are transferred from Diplocysta to Hypsotingis. 

InsectaArthropodanew combinationTingidaeTinginaeDiplocystaTingidaeHemipteraGenusHypsipyrgiasBotanyAnimaliaEcology Evolution Behavior and SystematicsTaxonomynew speciesNew GuineabiologyHeteropterakey to speciesAustraliaBiodiversityRusticabiology.organism_classificationHemipteraTinginaeKey (lock)Animal Science and ZoologyThaleiaHypsotingisZootaxa
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Dinotrema cavernicola sp. n. (Hymenoptera, Braconidae, Alysiinae), a new species of the genus Dinotrema Foerster from caves of Spain

2014

Dinotrema cavernicola sp. n. was collected in two caves in Spain. This is the first Dinotrema species known to occur in caves. This new species is described and compared to D. affine (Fischer, 1973) and D. collybiae Munk & Peris-Felipo, 2014, species sharing a mid-longitudinal carina on the propodeum.

InsectaKulbastaviaDinotremaHymenopteraCarbotripluridaBraconidaetaxonomyGenusPropodeumlcsh:ZoologyBilaterialcsh:QL1-991AlysiinaePterygotageography.geographical_feature_categorybiologyCephalornisCircumscriptional namesCavernicolaBoltonocostidaeIchneumonoideaTiphiinaeCircumscriptional nameBraconidaeCoelenterataArthropodaHymenopteridaNephrozoaProtostomiaBasalZoologyDinotrema cavernicolaAnimaliaCircumscriptional names of the taxon undercavesCaveEumetabolaBraconidaeCephalornisEcology Evolution Behavior and SystematicsAlysiinaeCystomastacoides kiddoAlysiinaeAnimalianew speciesgeographyHymenopteraAnimaliaDipteraStrashila incredibilisbiology.organism_classificationHymenopteraNotchiaInsect ScienceAlysiiniEcdysozoaJournal of Hymenoptera Research
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Fish tolerance to organophosphate-induced oxidative stress is dependent on the glutathione metabolism and enhanced by N-acetylcysteine

2003

Abstract Dichlorvos (2,2-dichlorovinyl dimethyl phosphate, DDVP) is an organophosphorus (OP) insecticide and acaricide extensively used to treat external parasitic infections of farmed fish. In previous studies we have demonstrated the importance of the glutathione (GSH) metabolism in the resistance of the European eel ( Anguilla anguilla L.) to thiocarbamate herbicides. The present work studied the effects of the antioxidant and glutathione pro-drug N -acetyl- l -cysteine (NAC) on the survival of a natural population of A. anguilla exposed to a lethal concentration of dichlorvos, focusing on the glutathione metabolism and the enzyme activities of acetylcholinesterase (AChE) and caspase-3 a…

InsecticidesAntioxidantHealth Toxicology and Mutagenesismedicine.medical_treatmentGlutathione reductaseMedizinApoptosisAquatic SciencePharmacologymedicine.disease_causeAcetylcysteinechemistry.chemical_compoundDichlorvosToxicity Tests AcutemedicineAnimalsProportional Hazards ModelsAnalysis of VarianceEelsDose-Response Relationship DrugMusclesOrganophosphateGlutathioneGlutathioneAcetylcysteineOxidative StressLiverchemistryBiochemistryDichlorvosToxicityNeurotoxicity SyndromesOxidative stressmedicine.drugAquatic Toxicology
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Increased recovery of brain acetylcholinesterase activity in dichlorvos-intoxicated European eels Anguilla anguilla by bath treatment with N-acetylcy…

2003

Organophosphate (OP) pesticides are widely used as antiparasitic chemicals in finfish aquaculture. However, current antidotes cannot be applied to treat intoxicated fish. We showed in previous studies the importance of glutathione (GSH) metabolism in pesticide resistance of the European eel Anguilla anguilla L. The present work studied the effects of the antioxidant and glutathione pro-drug N-acetyl-l-cysteine (NAC) on the recovery of European eels exposed for 96 h to a sublethal concentration (0.17 mg l^-1; 20% of its 96 h LC50) of the OP pesticide dichlorvos (2,2-dichlorovinyl dimethyl phosphate; DDVP). This insecticide and acaricide decreased muscular GSH content and increased oxidised g…

InsecticidesAntioxidantmedicine.medical_treatmentGlutathione reductaseMedizinmedicine.disease_causeAntioxidantsAcetylcysteinechemistry.chemical_compoundGlutathione metabolismUNESCO::CIENCIAS DE LA VIDAOrganophosphorus pesticideProdrugsUNESCO::CIENCIAS DE LA VIDA::Biología animal (Zoología):CIENCIAS DE LA VIDA::Biología animal (Zoología) [UNESCO]biologyOrganophosphateBrainCholinesterase inhibitorGlutathioneGlutathione ReductaseInactivation MetabolicAcetylcholinesteraseDetoxificationmedicine.drugEnvironmental Monitoringmedicine.medical_specialtyN-acetyl-l-cysteineAquatic Science:CIENCIAS DE LA VIDA [UNESCO]Internal medicineDichlorvosmedicineToxicity Tests AcuteAnimalsEcology Evolution Behavior and SystematicsCholinesteraseOrganophosphate poisoningAnalysis of VarianceDetoxification ; Organophosphorus pesticide ; Organophosphate poisoning ; Cholinesterase inhibitor ; Oxidative stress ; N-acetyl-l-cysteine ; AChE ; Glutathione metabolismDose-Response Relationship DrugBathsGlutathioneAnguillaAcetylcysteineEndocrinologychemistryOxidative stressDichlorvosbiology.proteinAChECholinesterase InhibitorsOxidative stressWater Pollutants Chemical
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