Search results for "D.3.1"
showing 10 items of 30 documents
Prognostic value of the interaction between galectin-3 and antigen carbohydrate 125 in acute heart failure
2015
AIM:Galectin-3 (Gal-3) and carbohydrate antigen 125 (CA125) have emerged as robust prognostic biomarkers in heart failure. Experimental data have also suggested a potential molecular interaction between CA125 and Gal-3; however, the biological and clinical relevance of this interaction is still uncertain. We sought to evaluate, in patients admitted for acute heart failure, the association between plasma Gal-3 with all-cause mortality and the risk for rehospitalizations among high and low levels of CA125. METHODS AND RESULTS: We included 264 consecutive patients admitted for acute heart failure to the Cardiology Department in a third-level center. Both biomarkers were measured on admission. …
Malignancy Risk Models for Oral Lesions
2013
Objectives: The aim of this work was to assess risk habits, clinical and cellular phenotypes and TP53 DNA changes in oral mucosa samples from patients with Oral Potentially Malignant Disorders (OPMD), in order to create models that enable genotypic and phenotypic patterns to be obtained that determine the risk of lesions becoming malignant. Study Design: Clinical phenotypes, family history of cancer and risk habits were collected in clinical histories. TP53 gene mutation and morphometric-morphological features were studied, and multivariate models were applied. Three groups were estabished: a) oral cancer (OC) group (n=10), b) OPMD group (n=10), and c) control group (n=8). Results: An avera…
Analysis of the road traffic management system in the neural network development perspective
2019
The research goal of the paper is to present the issues connected with road traffic management systems and to illustrate a management system that uses Intelligent Transportation Systems and neural networks. The use of Intelligent Transportation Systems (ITS) is a method of improving the conditions of communications, making it independent from the development of communications infrastructure. The attributes of neural networks are focused on solving the problems of optimisation, which involve the development of optimal strategies for traffic management. The proposed road traffic management system that uses ITS and neural networks can be applied in prediction of the conditions of communication…
Use of UML and Model Transformations for Workflow Process Definitions
2006
Currently many different modeling languages are used for workflow definitions in BPM systems. Authors of this paper analyze the two most popular graphical languages, with highest possibility of wide practical usage - UML Activity diagrams (AD) and Business Process Modeling Notation (BPMN). The necessary in practice workflow aspects are briefly discussed, and on this basis a natural AD profile is proposed, which covers all of them. A functionally equivalent BPMN subset is also selected. The semantics of both languages in the context of process execution (namely, mapping to BPEL) is also analyzed in the paper. By analyzing AD and BPMN metamodels, authors conclude that an exact transformation …
La tipografía en el cine: : análisis de cabeceras y créditos de películas como estrategia educativa desde la cultura visual
2013
En el presente artículo se recogen un conjunto de relexiones sobre papel que adquieren los textos escritos utilizados como imágenes en el discurso cinematográico. Las letras del alfabeto han estado íntimamente unidas a la tradición del cine desde sus inicios. Esta atracción mutua que ha existido siempre entre el alfabeto y el cine ha generado un extraordinario legado que podemos analizar mediante los postulados de la cultura visual. Sugerimos la oportunidad de utilizar este elemento visual para solventar algunos errores, empobrecimientos, insuiciencias y déicits que pueden observarse en buena parte de los rituales educativos convencionales, ya que las letras como signos son artefactos visua…
Classification of current anticancer immunotherapies.
2014
© 2014. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Repeat Assessed Values Model for Housing Price Index
2017
Abstract This study proposes an innovative methodology, named Repeat Appraised Price Model (RAV), useful for determining the price index numbers for real estate markets and the corresponding index numbers of hedonic prices of main real estate characteristics in the case of a lack of data. The methodological approach proposed in this paper aims to appraise the time series of price index numbers. It integrates the principles of the method of repeat sales with the peculiarities of the Hedonic Price Method, overcoming the problem of an almost total absence of repeat sales for the same property in a given time range; on the other hand, the technique aims to overcome the limitation of the repeat …
Tiam1 as a Signaling Mediator of Nerve Growth Factor-Dependent Neurite Outgrowth
2010
Nerve Growth Factor (NGF)-induced neuronal differentiation requires the activation of members of the Rho family of small GTPases. However, the molecular mechanisms through which NGF regulates cytoskeletal changes and neurite outgrowth are not totally understood. In this work, we identify the Rac1-specific guanine exchange factor (GEF) Tiam1 as a novel mediator of NGF/TrkA-dependent neurite elongation. In particular, we report that knockdown of Tiam1 causes a significant reduction in Rac1 activity and neurite outgrowth induced by NGF. Physical interaction between Tiam1 and active Ras (Ras- GTP), but not tyrosine phosphorylation of Tiam1, plays a central role in Rac1 activation by NGF. In add…
The urban rent in the multicultural city: retail shops, migrants and urban decline in the historic centre of Palermo [La rendita urbana nella città m…
2020
Changes in consumer shopping behavior and in retail spaces, such as shopping malls, department stores and e-commerce, have modified localization models of traditional retail shops, also affecting urban fabric and spatial distribution of urban rent. Even city centers have undergone significant transformations or even decline, especially if local economic system and real estate market are weak and recessionary. A significant amount of commercial properties may have long vacancy due to excess supply, since many traditional shops close their business because they are no longer competitive and, moreover, there is no immediate takeover by new tenants. The decline of central urban areas depends on…
The use of social media for knowledge acquisition and dissemination in B2B companies: an empirical study of Finnish technology industries
2019
Scholars and practitioners of knowledge management have paid increasing attention to the adoption of social media in business-to-business (B2B) setting for knowledge sharing; however, both the theoretical and empirical research in this domain are quite fragmented. The aim of this research is to deepen the understanding about the B2B companies’ awareness of the potentials of social media in improving their absorptive capacity and, consequently, if and how such companies deploy knowledge strategies based on social media adoption. We carried out an empirical survey of Finnish technology companies operating purely in B2B markets. Results highlight that social media adoption is still in a prelim…