Search results for "D11"

showing 10 items of 337 documents

Expression of KIT (CD117) in Biphasic Pulmonary Blastoma. Novel Data on Histogenesis

2003

Biphasic pulmonary blastoma (BPB) is a rare primary neoplasm of the lung and its histogenesis is still uncertain. It has been proposed that BPB is derived from mesoderm or endoderm. Others suggested an origin from a single pluripotential cell. We present a case of a BPB with emphasis on expression of the stem cell factor receptor KIT (CD117). We describe a 61-year-old male patient with a BPB of the upper right lobe. Immunohistochemical analysis was performed using a panel of several antibodies including anti-CD117. Strong cytoplasmic expression of CD117 was found in the epithelium (cytokeratin-positive) as well as in the spindle cells (cytokeratin-negative). Expression of CD117 in both mese…

MalePulmonary and Respiratory MedicineMesodermPathologymedicine.medical_specialtyLung NeoplasmsStromal cellbiologyCD117Biphasic Pulmonary BlastomaMesenchymal stem cellStem cell factorMiddle AgedHistogenesisImmunohistochemistrydigestive system diseasesProto-Oncogene Proteins c-kitmedicine.anatomical_structurebiology.proteinmedicineHumansEndodermLungLung
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Down regulation of CD11b and CD18 expression in children with hypercholesterolemia: A preliminary report.

2009

BACKGROUND AND AIM: Cell adhesion molecules play an important role in the development of atherosclerosis mediating the attachment of monocytes to the endothelium. The aim of our study was to assess the cell surface expression of CD11b/CD18 integrin on the phagocytes of children affected by hypercholesterolemia. METHODS AND RESULTS: Twenty-six children with hypercholesterolemia (15 males, mean age 8.3, range 2-18) with a family history of early cardiovascular disease, as well as 26 children with normocholesterolemia matched for gender and age (15 males, mean age 8.3) were studied. Cell surface expression of CD11b/CD18 on peripheral blood mononuclear cells (PBMC) were analyzed by flow cytomet…

MaleSettore MED/09 - Medicina InternaAdolescentEndotheliumEndocrinology Diabetes and MetabolismDown-RegulationMedicine (miscellaneous)Pilot ProjectsCD18Context (language use)Peripheral blood mononuclear cellFlow cytometrychildrencd11b/cd18HumansMedicineFamily historyChildCD18PhagocytesCD11b AntigenNutrition and Dieteticsatherosclerosis; cd11b; cd11b/cd18; cd18; children; hypercholesterolemiahypercholesterolemiamedicine.diagnostic_testbiologybusiness.industryCell adhesion moleculeCD11bLipidsCross-Sectional Studiesmedicine.anatomical_structureIntegrin alpha MCD18 AntigensCase-Control StudiesChild PreschoolImmunologybiology.proteinFemaleatherosclerosisCardiology and Cardiovascular Medicinebusiness
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Gastrointestinal stromal tumour of the rectum: Report of a case and review of literature

2008

Gastrointestinal stromal tumour (GIST) is a rare tumour of the gastrointestinal tract which does not generally originate in the rectum. The authors describe a case of a 70-year-old man who underwent an anterior resection of the rectum for a low-risk GIST. The patient was not given adjuvant chemotherapy with imatinib and is still disease-free 30 mo after surgery. The authors conclude that although rectal GIST is extremely uncommon, it should be included in differential diagnosis when a tumour in the rectum is detected. Biopsy of the tumour is essential, since this makes it possible to reach a sure preoperative diagnosis based on the immunohistological features of the CD117 and CD34. Although…

Malemedicine.medical_specialtyGastrointestinal Stromal TumorsCD34RectumAntigens CD34Antineoplastic AgentsCase ReportPiperazinesGIST;BiopsymedicineHumansneoplasmsAgedGastrointestinal tractGiSTmedicine.diagnostic_testbiologyRectal NeoplasmsCD117business.industryGastroenterologyGeneral MedicineCombined Modality Therapydigestive system diseasesSurgeryProto-Oncogene Proteins c-kitPyrimidinesTreatment Outcomemedicine.anatomical_structureImatinib mesylateBenzamidesImatinib Mesylatebiology.proteinDifferential diagnosisbusinessGISTWorld Journal of Gastroenterology
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Granulocyte integrins before and after activation in acute ischaemic stroke.

2001

We examined in 19 subjects with acute ischaemic stroke (AIS) the PMN integrin pattern (CD11a, CD11b, CD11c, CD18), using indirect immunofluorescence and adopting a flow cytometer, at baseline and during activation, prolonged for 5 and 15 min, with 4-phorbol 12-myristate 13-acetate (PMA). At baseline, an increase in the expression of CD11c and CD18 and a decrease in the CD11b were evident in AIS subjects compared to normals. After activation, we found in normals a constant and significant increase of all PMN adhesive molecules, while in AIS subjects, we found an increase in CD11b and CD18, a decrease in CD11a and no variation in CD11c. While the basal upregulation of CD11c and CD18 may depen…

Malemedicine.medical_specialtyIntegrinsIntegrinCD11cIntegrin alphaXbeta2Macrophage-1 Antigenchemical and pharmacologic phenomenaCD18CD11aGranulocyteBrain IschemiaDownregulation and upregulationInternal medicinemedicineHumansFluorescent Antibody Technique IndirectAgedAged 80 and overintegumentary systembiologybusiness.industryhemic and immune systemsMiddle AgedPathophysiologyLymphocyte Function-Associated Antigen-1StrokeChemotaxis LeukocyteEndocrinologymedicine.anatomical_structureNeurologyIntegrin alpha MCD18 AntigensImmunologyAcute Diseasebiology.proteinCarcinogensTetradecanoylphorbol AcetateFemaleNeurology (clinical)businessGranulocytesJournal of the neurological sciences
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Polymorphonuclear leukocyte integrin pattern, at baseline and after activation, in type 2 diabetic subjects with macrovascular complications.

2003

In vascular atherosclerotic disease and in diabetes mellitus few studies have evaluated the polymorphonuclear leukocyte (PMN) adhesion molecule pattern. In this study we examined the PMN integrin expression at baseline and after activation in controls and type 2 diabetic subjects with macrovascular complications (MVC). We enrolled 21 subjects with type 2 diabetes mellitus and macrovascular complications, localized in peripheral, coronary and cerebral sites. The patients had peripheral occlusive arterial disease, chronic cerebrovascular disease or coronary heart disease. We evaluated the expression of some PMN integrins (CD11a, CD11b, CD11c, CD18), using flow cytofluorimetry, at baseline and…

Malemedicine.medical_specialtyIntegrinsNeutrophilsEndocrinology Diabetes and MetabolismIntegrinCD11cchemical and pharmacologic phenomenaCD18CD11aEndocrinologyInternal medicineDiabetes mellitusInternal MedicinemedicineHumansCD11a AntigenAgedCD11b AntigenbiologyCell adhesion moleculebusiness.industryType 2 Diabetes Mellitushemic and immune systemsGeneral MedicineMiddle Agedmedicine.diseaseCD11c AntigenEndocrinologyIntegrin alpha MDiabetes Mellitus Type 2CD18 Antigensbiology.proteinTetradecanoylphorbol AcetateFemalebusinessDiabetic AngiopathiesActa diabetologica
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Roca Cabau, G. (2020). Pobresa i hospitals a la Lleida baixmedieval. Lleida: Pagès editors. 260 pp. ISBN: 978-84-1303-228-3

2021

Resenya: Roca Cabau, G. (2020). Pobresa i hospitals a la Lleida baixmedieval. Lleida: Pagès editors. 260 pp. ISBN: 978-84-1303-228-3.

Medieval historyD111-203General MedicineAnales de la Universidad de Alicante. Historia Medieval
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Furió, A. (Ed.) (2020). En torno a la economía mediterránea medieval. Estudios dedicados a Paulino Iradiel. València: Publicacions de la Universitat …

2021

Reseña: Furió, A. (Ed.) (2020). En torno a la economía mediterránea medieval. Estudios dedicados a Paulino Iradiel. València: Publicacions de la Universitat de València, 2020. 402 pp. ISBN: 978-84-9134-661-6.

Medieval historyD111-203General MedicineAnales de la Universidad de Alicante. Historia Medieval
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Escartí, V. J. y Roca Ricart, R. (2021). En los márgenes de la Historia: marginales y minorías. Saragossa: Libros Pórtico. 305 pp. ISBN: 978-84-7956-…

2021

Resenya: Escartí, V. J. y Roca Ricart, R. (2021). En los márgenes de la Historia: marginales y minorías. Saragossa: Libros Pórtico. 305 pp. ISBN: 978-84-7956-208-3.

Medieval historyD111-203General MedicineAnales de la Universidad de Alicante. Historia Medieval
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El reinado del Cornificio y el exilio de las Musas. El filósofo educado en las Artes en la Antigüedad arcaica y en la Europa medieval hasta el siglo …

2016

Resumen: Este estudio describe y analiza el tránsito de un paradigma educativo (antiguo, clásico y medieval) a un nuevo paradigma (el universitario, hacia el siglo XII). Se examina el origen y el desarrollo de un paradigma educativo y de formación que se remonta hasta la Grecia arcaica y que se mantuvo en vigencia en la Europa medieval hasta la creación de las universidades en el siglo XII. La tradición educativa de las artes liberales, conocida también como disciplinae cyclicae, es analizado como heredero directo de la tradición arcaica y pitagórica griega basada en la formación por las Musas. Se examinarán las similitudes y paralelismos entre las Musas y las Artes a la luz de la obra de M…

Medieval philosophyHistoryUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASLiberal arts educationLiterature and Literary TheoryFilologíasmedia_common.quotation_subjectlcsh:Literature (General)filosofía del artelcsh:D111-203lcsh:Medieval historyFilologías. Generalidadesfilología clásicaArtlcsh:PN1-6790universidad medievalLanguage and Linguisticsartes liberalesfilosofía medievallcsh:D204-475:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]Humanitieslcsh:Modern history 1453-media_common
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Leggere il diritto nella prospettiva del genere e viceversa

2021

Il contributo illustra uno dei filoni tematici del volume di O. Cavallar e J. Kirshner, ovvero il ruolo del genere nell���ordine giuridico, e sottolinea l���importanza del diritto per affrontare la storia delle identit�� di genere e soprattutto per promuovere la storia della mascolinit��.

Medioevo Italia Diritto comune Storia del diritto Diritto e società Storia di genereLanguage and LiteratureD111-203PItaliaStoria del dirittoStoria di genereMiddle Ages Italy Ius commune Law History Law and Society Gender HistorySettore IUS/19 - Storia Del Diritto Medievale E ModernoArchaeologyMedioevoDiritto comuneMedieval historyDiritto e societàCC1-960D111 Medieval HistoryReti Medievali Rivista
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