Search results for "D2"
showing 10 items of 2418 documents
Strategies for Improving Optimal Positioning of Quality Sensors in Urban Drainage Systems for Non-Conservative Contaminants
2021
In the urban drainage sector, the problem of polluting discharges in sewers may act on the proper functioning of the sewer system, on the wastewater treatment plant reliability and on the receiving water body preservation. Therefore, the implementation of a chemical monitoring network is necessary to promptly detect and contain the event of contamination. Sensor location is usually an optimization exercise that is based on probabilistic or black-box methods and their efficiency is usually dependent on the initial assumption made on possible eligibility of nodes to become a monitoring point. It is a common practice to establish an initial non-informative assumption by considering all network…
Llengua i espiritualitat en la Vita Christi d’Isabel de Villena
2015
Resum:La Vita Christi de sor Isabel de Villena es gestà en la dècada dels 60 del segle XV a partir dels tractats que l’abadessa del monestir de la Trinitat de València usava per a formar les seues monges i per a suscitar en elles la contemplació de Jesús a través dels ulls de Maria i de les dones que l’envoltaren. La comparació de la llengua i de l’estil del Tractat de la Passió i els de les edicions de 1497 i 1513 ha permès comprovar que aquells s’adaptaren a la sensibilitat religiosa i lingüística de cada moment. El llenguatge de l’abadessa, culte i popular alhora, no es deixà influir pel de Corella. Tanmateix, sor Aldonça de Montsoriu, l’editora de l’incunable, intentà 'vendre' l’«elegan…
Kredītiestāžu pienākums nodrošināt maksājumu un elektroniskās naudas iestādēm piekļuvi maksājuma konta pakalpojumiem.
2021
Kredītiestāžu pienākums nodrošināt maksājumu iestādēm un elektroniskās naudas iestādēm objektīvu, samērīgu un nediskriminējošu piekļuvi kredītiestādes sniegtajiem maksājumu konta pakalpojumiem ir būtisks nosacījums maksājumu iestāžu un elektroniskās naudas iestāžu pastāvēšanai un sekmīgai darbībai. Tas tā ir, jo šo iestāžu pastāvēšana ir priekšnosacījums konkurencei un inovācijām maksājumu pakalpojumu tirgū, kas ir īpaši svarīgi ņemot vērā Eiropas Savienības nostāju, ka konkurence un inovācijas ir viens no vienota maksājumu tirgus mērķiem. Latvijā šis jautājums nav pētīts un publiski ir dzirdēti reti gadījumi, kad maksājumu iestādes vērsušās Finanšu un Kapitāla tirgus komisijā vai Konkurenc…
Collective Locomotion of Human Cells, Wound Healing and Their Control by Extracts and Isolated Compounds from Marine Invertebrates
2020
The collective migration of cells is a complex integrated process that represents a common theme joining morphogenesis, tissue regeneration, and tumor biology. It is known that a remarkable amount of secondary metabolites produced by aquatic invertebrates displays active pharmacological properties against a variety of diseases. The aim of this review is to pick up selected studies that report the extraction and identification of crude extracts or isolated compounds that exert a modulatory effect on collective cell locomotion and/or skin tissue reconstitution and recapitulate the molecular, biochemical, and/or physiological aspects, where available, which are associated to the substances und…
Succesio ab intestato: Concerning the death of Rodrigo de Mendoza, I Marquis of the Cenete
2017
La muerte de Rodrigo de Mendoza, I marqués del Cenete, sin testamento se vio envuelta de la incertidumbre propia del fallecimiento de un noble con un cuantioso patrimonio heredado en gran parte de su padre, el gran cardenal de España, sin especificar ni repartir y con tres hijas menores huérfanas sin un albacea designado por él. El gobernador general de Valencia, Lluís de Cabanyelles, del círculo más íntimo del marqués durante su estancia en la ciudad del Turia, junto a otros partícipes y testigos, impulsó el proceso de inventariado de todos sus bienes cuatro días después de su defunción, apelando, asimismo, al emperador Carlos V para que confirmase al virrey del reino de Valencia y hermano…
Analysis of DRD2 Gene Polymorphism in the Context of Personality Traits in a Group of Athletes
2021
The presented study showed the relationship between dopamine receptor gene polymorphism and personality traits in athletes training in martial arts. Behavioral modulation resulting from a balance of the neurotransmitters dopamine and norepinephrine to inactivation of the dorsolateral prefrontal cortex and dysregulation of various pathways involved in attention and impulse control processes
La Unión Liberal en el sistema político isabelino. Concepciones, alcances y limitaciones (1858-1863) The Liberal Union in the political Elizabethan s…
2017
Este artículo pretende revisar el estado actual de conocimientos sobre una formación política, la Unión Liberal, que presidió el Gobierno más largo y estable de la era isabelina. El unionismo es un proyecto político que tradicionalmente ha sufrido la desatención de la historiografía por ser considerado continuación o solución estratégica para que el moderantismo clásico se perpetuase en el poder. Mi investigación trata de cuestionar esta línea interpretativa y enfatizar que el unionismo puede agrietar más si cabe la tesis de la debilidad del liberalismo español.La Unión Liberal fue un experimento político, original e innovador, que bajo premisas ya contempladas en la cultura liberal, reinte…
Essential Oil Composition of Alluaudia procera and in Vitro Biological Activity on Two Drug-Resistant Models
2019
Drug resistance is a major obstacle in antibiotic and antitumor chemotherapy. In response to the necessity to find new therapeutic strategies, plant secondary metabolites including essential oils (EOs) may represent one of the best sources. EOs in plants act as constitutive defenses against biotic and abiotic stress, and they play an important role in the pharmacology for their low toxicity, good pharmacokinetic and multitarget activity. In this context, natural products such as EOs are one of the most important sources of drugs used in pharmaceutical therapeutics. The aim of this paper was to identify the chemical composition of the essential oil of Alluaudia procera leaves, obtained by hy…
Kaempferol as a dietary anti-inflammatory agent: current therapeutic standing
2020
Inflammation is a physiological response to different pathological, cellular or vascular damages due to physical, chemical or mechanical trauma. It is characterized by pain, redness, heat and swelling. Current natural drugs are carefully chosen as a novel therapeutic strategy for the management of inflammatory diseases. Different phytochemical constituents are present in natural products. These phytochemicals have high efficacy both in vivo and in vitro. Among them, flavonoids occur in many foods, vegetables and herbal medicines and are considered as the most active constituent, having the ability to attenuate inflammation. Kaempferol is a polyphenol that is richly found in fruits, vegetabl…
IFN-alpha Stimulates Proliferation and Cytokine Secretion of CD40-Stimulated B Cell Chronic Lymphocytic Leukemia Cells In Vitro
1999
Interferon (IFN)-alpha has a therapeutic effect in several B cell malignancies, including low-grade non-Hodgkin's lymphoma (NHL), multiple myeloma, and hairy cell leukemia, whereas its efficacy in the treatment of B cell chronic lymphocytic leukemia (B-CLL) is rather limited. In the present study, we investigated the effect of IFN-alpha on the biologic functions of B-CLL cells, which were stimulated by cross-linking of the CD40 antigen. In cell samples from 16 B-CLL patients, the addition of IFN-alpha to CD40-stimulated purified B-CLL cells caused a significant increase in [3H]thymidine uptake (p < 0.003). In B-CLL cells maximally activated by CD40 cross-linking and interleukin-2 (IL-2)/IL-…