Search results for "DAS"
showing 10 items of 4164 documents
Die allergisch-hyperergische Entzündung von Haut und Gelenken unter dem Einflu\ von Hyaluronidase und Rutin
1954
Es wurde der Einflu\ von Hyaluronidase und Rutin auf die allergisch-hyperergische Entzundung der Haut und der Gelenke beim Kaninchen untersucht. Hyaluronidase allein ruft lediglich ein entzundliches odem hervor. Hyaluronidase am Ort der Antigenreinjektion appliziert fuhrt in der Haut zu einer AbschwAchung und im Gelenk zu einer VerstArkung der Entzundung. Intravenose Hyaluronidasegaben verstArken die Entzundung in der Haut, wAhrend die Arthritis keine wesentliche Beeinflussung erfAhrt. Rutin intravenos gegeben fuhrt zu einer deutlichen Herabminderung der Entzundungserscheinungen an Haut und Gelenken.
Seno valodu profesors Pauls Žibeiks un viņa metode (1987.-1992.)
2010
Professor Pauls Žibeiks usually is mentioned as professor of Old Testament. In my memories P. Žibeiks takes place of the professor of ancient languages, which he taught in the theological seminary. During the period of time 1987-1992 I was in close touch with the professor, first being his student in his classes of ancient languages in the seminary rooms in Jāņa street, and after, visiting him in Bauska with certain regularity. Here, professor's Pauls Žibeiks teaching method is briefly considered in context of language teaching methods in the Rīga Domskola, the Theological faculty of University of Latvia and the Lutheran theological seminary.
Targeting SARS-CoV-2 Main Protease for Treatment of COVID-19: Covalent Inhibitors Structure-Activity Relationship Insights and Evolution Perspectives
2022
The viral main protease is one of the most attractive targets among all key enzymes involved in the SARS-CoV-2 life cycle. Covalent inhibition of the cysteine145 of SARS-CoV-2 MPRO with selective antiviral drugs will arrest the replication process of the virus without affecting human catalytic pathways. In this Perspective, we analyzed the in silico, in vitro, and in vivo data of the most representative examples of covalent SARS-CoV-2 MPRO inhibitors reported in the literature to date. In particular, the studied molecules were classified into eight different categories according to their reactive electrophilic warheads, highlighting the differences between their reversible/irreversible mech…
Skaidras naudas darījumu ierobežojumi, to normatīvais regulējums un atbilstība Satversmei
2020
Nesen ir stājušies spēkā vairāki normatīvo aktu grozījumi, kas paredz fiziskām personām, kas neveic saimniecisko darbību, ierobežojumus savos darījumos lietot skaidru naudu. Šādi ierobežojumi darba autores uzskatā var ierobežot cilvēku pamattiesības. Darbā tiek pētīti: naudas vēsturiskā attīstība, skaidras naudas lietošanu regulējošs normatīvais regulējums Latvijā, citu valstu pieredze skaidras naudas lietošanas ierobežošanas jautājumos, kā arī tiek analizētas konkrētas skaidras naudas lietošanu ierobežojošas normas un šo normu atbilstība Latvijas Republikas Satversmei. SKAIDRA NAUDA. SKAIDRAS NAUDAS LIETOŠANAS IEROBEŽOJUMI. CILVĒKTIESĪBU IEROBEŽOJUMI. SATVERSMES 105.PANTS.
Study of enzymatic activity in human neuroblastoma cells SH-SY5Y exposed to zearalenone's derivates and beauvericin.
2021
Abstract Beauvericin (BEA), α-zearalenol (α-ZEL) and β-zearalenol (β-ZEL), are produced by several Fusarium species that contaminate cereal grains. These mycotoxins can cause cytotoxicity and neurotoxicity in various cell lines and they are also capable of produce oxidative stress at molecular level. However, mammalian cells are equipped with a protective endogenous antioxidant system formed by no-enzymatic antioxidant and enzymatic protective systems such as glutathione peroxidase (GPx), glutathione S-transferase (GST), catalase (CAT) and superoxide dismutase (SOD). The aim of this study was evaluating the effects of α-ZEL, β-ZEL and BEA, on enzymatic GPx, GST, CAT and SOD activity in huma…
Una aproximación volumétrica a la desagregación espacial de la población combinando cartografía temática y datos LIDAR
2016
La disponibilidad de información sobre la distribución de la población a gran escala, e independiente de las unidades administrativas de recogida de la información, es una necesidad en muchos ámbitos: evaluación de riesgos de terremotos, inundaciones o incendios, integración de estadísticas demográficas con información medioambiental en formatos diversos, diseño de políticas de prestación de servicios públicos o estudios de accesibilidad y movilidad en las grandes ciudades. Por estas razones, la literatura ha explorado numerosos métodos de desagregación de la población, recogida a nivel municipal o de sección censal, en polígonos urbanos procedentes de los sistemas de información de cobertu…
A population density grid for Spain
2013
This article describes a high-resolution land cover data set for Spain and its application to dasymetric population mapping (at census tract level). Eventually, this vector layer is transformed into a grid format. The work parallels the effort of the Joint Research Centre (JRC) of the European Commission, in collaboration with Eurostat and the European Environment Agency (EEA), in building a population density grid for the whole of Europe, combining CORINE Land Cover with population data per commune. We solve many of the problems due to the low resolution of CORINE Land Cover, which are especially visible with Spanish data. An accuracy assessment is carried out from a simple aggregation of …
Intestinal anti-inflammatory activity of ellagic acid in the acute and chronic dextrane sulfate sodium models of mice colitis.
2013
Abstract Ethnopharmacological relevance Pomegranate (Punica granatum L.; Lythraceae) has traditionally been used for the treatment of various inflammatory diseases, including ulcerative colitis (UC). Because its fruits and extracts are rich in ellagitannins, which release ellagic acid when hydrolyzed, consumption of pomegranate products is currently being widely promoted for their potential health effects, including the prevention of inflammatory diseases and cancer. To evaluate the anti-inflammatory effects of ellagic acid on dextran sulfate sodium (DSS)-induced acute and chronic experimental colitis in two different strains of mice and to elucidate its possible mechanisms of action. Mater…
The Valencia Eustress-Distress Appraisal Scale (VEDAS): Validation of the Italian Version
2018
© 2018 by the authors. The aim of this study is to validate the Italian version of the Valencia Eustress-Distress Appraisal Scale (VEDAS). Two hundred and thirty-two Italian workers were involved in the study. Dimensionality, reliability, and concurrent validity were analyzed. Confirmatory factor analysis supported a four-dimensional structure. In addition, the Italian version of the scale showed good internal consistency and validity. The results indicate that the Italian version of the VEDAS is a valid instrument for measuring eustress and distress appraisal in the Italian context. ispartof: SUSTAINABILITY vol:10 issue:11 status: published
Dasatiniba solvātu iegūšana un raksturošana
2016
Dasatiniba solvātu iegūšana un raksturošana. Čerņavska K., Darba vadītājs vadošā pētniece Dr. chem. Orola L., Maģistra darbs, 51 lappuses, 24 attēli, 18 tabulas, 71 literatūras avoti. Latviešu valodā. Darbā ir veikta dasatiniba solvātu iegūšana ar sekojošiem šķīdinātājiem: acetonitrilu, nitrometānu, etilacetātu, acetonu, 1,4-dioksānu, 1,3-dioksalānu, butilacetātu, tetrahidrofurānu, izopropilalkoholu, metiletilketonu, metilacetātu, n-propanolu, izobutanolu, n-butanolu, izopropilacetātu, etanolu, toluolu un dimetilsulfoksīdu. Iegūtie solvāti tika analizēti ar pulvera rentgendifraktometrijas metodi un diferenciālās termiskās analīzes/termogravimetrijas (DTA/TG) metodi. Iegūtajiem solvātiem tik…