Search results for "DAS"

showing 10 items of 4164 documents

Variation and covariation in infectivity, virulence and immunodepression in the host-parasite association Gammarus pulex-Pomphorhynchus laevis.

2009

Parasites often manipulate host immunity for their own benefit, either by exacerbating or suppressing the immune response and this may directly affect the expression of parasite virulence. However, genetic variation in immunodepression, which is a prerequisite to its evolution, and the relationship between immunodepression and virulence, have rarely been studied. Here, we investigated the variation among sibships of the acanthocephalan parasite, Pomphorhynchus laevis , in infecting and in immunodepressing its amphipod host, Gammarus pulex . We also assessed the covariation between infectivity, parasite-induced immune depression and host mortality (parasite virulence). We found that infecti…

0106 biological sciencesVirulencephenoloxidaseparasite-induced immunodepression[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyMicrobiologyAcanthocephalaHost-Parasite Interactions03 medical and health sciencesImmune systemRiversImmunityResearch articlesImmune Tolerance[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisParasite hostingAnimalsAmphipoda030304 developmental biologyGeneral Environmental ScienceInfectivity0303 health sciences[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyGeneral Immunology and MicrobiologybiologycovariationHost (biology)Monophenol MonooxygenaseGeneral Medicinebiology.organism_classificationSurvival Analysis3. Good healthacanthocephalanvirulenceGammarus pulex[SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyImmunologyimmune defencesPomphorhynchus laevisFrance[SDE.BE]Environmental Sciences/Biodiversity and EcologyGeneral Agricultural and Biological Sciences[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Effect of acyl-CoA oxidase activity on the accumulation of gamma-decalactone by the yeast Yarrowia lipolytica: a factorial approach.

2007

International audience; beta-Oxidation is a cyclic pathway involved in the degradation of lipids. In yeast, it occurs in peroxisomes and the first step is catalyzed by an acyl-CoA oxidase (Aoxp). The yeast Yarrowia lipolytica possesses several genes (POX) coding for Aoxps. This study is based on the factorial analysis of results obtained with the many POX derivative strains that have been constructed previously. The effect of interactions between Aoxps on the acyl-CoA oxidase (Aox) activity was important even at the second order. We then investigated the effect of Aox activity on growth and lactone production. Aox activity was correlated with acidification of the medium by cells and with ce…

0106 biological sciencesYarrowia lipolyticaMESH: Enzyme ActivationMetabolic Clearance RateMESH: Factor Analysis StatisticalYarrowiaBiologymodèleModels Biological01 natural sciencesApplied Microbiology and BiotechnologyLactones03 medical and health sciencesEnzyme activatorSpecies SpecificityMESH: Computer Simulation010608 biotechnologyCombinatorial Chemistry TechniquesAcyl-CoA oxidaseMESH: Species SpecificityComputer Simulation030304 developmental biologychemistry.chemical_classificationMESH: Metabolic Clearance Rate0303 health sciencesOxidase testmétabolisme des acides grasAcyl-CoA oxidase activityMESH: Acyl-CoA OxidaseMESH: Models BiologicalYarrowia[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyGeneral MedicinePeroxisomebiology.organism_classificationYeastEnzyme ActivationBiochemistrychemistrylactoneMolecular MedicineMESH: Combinatorial Chemistry TechniquesMESH: YarrowiaAcyl-CoA OxidaseFactor Analysis StatisticalLactoneMESH: Lactones
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No evidence of an immune adjustment in response to a parasitoid threat in Lobesia botrana larvae.

2017

5 pages; International audience; Immune function is a key determinant of an organism's fitness, and natural insect populations are highly variable for this trait, mainly due to environmental heterogeneity and pathogen diversity. We previously reported a positive correlation between infection prevalence by parasitoids and host immunity in natural populations of the vineyard pest Lobesia botrana. Here, we tested whether this correlation reflects a plastic adjustment of host immunity in response to the local presence of parasites. To this end, we measured immunity of non-parasitized L. botrana larvae exposed, respectively, to one of the two most common species of parasitoids in vineyards, over…

0106 biological sciences[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyHemocytesPlasticityPhysiologymedia_common.quotation_subjectWaspsInsectMothsLobesia botrana010603 evolutionary biology01 natural sciences[SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunityParasitoidImmune systemCommon speciesImmunity[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimals[ SDV.IMM ] Life Sciences [q-bio]/Immunology[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyComputingMilieux_MISCELLANEOUSmedia_commonLarvaEnzyme PrecursorsbiologyGrapevine mothEcologyProphylaxis[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]fungiCampoplex capitatorbiology.organism_classification[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology010602 entomologyPhytomiptera nigrinaInsect ScienceLarvaInsect immunityInsect Proteins[SDV.IMM]Life Sciences [q-bio]/ImmunologyPEST analysisCatechol Oxidase[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Los foros y las redes sociales ayudan a descubrir especies exóticas en Europa y monitorear su propagación: el caso de Exaireta spinigera (Wiedemann, …

2018

La mosca soldado Exaireta spinigera (Wiedemann, 1830) (Diptera, Stratiomyidae) es originaria de Australia y se introdujo en Hawái, América del Norte y se está extendiendo rápidamente por Europa. Comentamos el conocimiento sobre su presencia en Italia y publicamos los primeros registros de Sicilia. El conocimiento existente sobre la llegada y distribución de esta especie en Italia se fundamenta exclusivamente en datos proporcionados por ciudadanos a través de foros de internet y grupos de Facebook sobre biodiversidad, que así han demostrado ser una ayuda útil para la difícil detección de especies invasoras.

0106 biological sciencesbiology010604 marine biology & hydrobiologyespecies invasorasStratiomyidaebiology.organism_classificationdiptera010603 evolutionary biology01 natural sciencesSoldier flyInvasive speciesbiodiversidadespecies introducidasGeographyQL1-991Animal Science and Zoologyciencia ciudadanastratiomyidaeHumanitiesZoologyEcology Evolution Behavior and SystematicsGraellsia
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Nitric oxide production mediates oligogalacturonide-triggered immunity and resistance to Botrytis cinerea in Arabidopsis thaliana

2012

Nitric oxide (NO) regulates a wide range of plant processes from development to environmental adaptation. In this study, we investigated the production and/or function of NO in Arabidopsis thaliana leaf discs and plants elicited by oligogalacturonides (OGs) and challenged with Botrytis cinerea. We provided evidence that OGs triggered a fast and long lasting NO production which was Ca(2+) dependent and involved nitrate reductase (NR). Accordingly, OGs triggered an increase of both NR activity and transcript accumulation. NO production was also sensitive to the mammalian NO synthase inhibitor L-NAME. Intriguingly, we showed that L-NAME affected NO production by interfering with NR activity, t…

0106 biological scienceschemistry.chemical_classification0303 health sciencesReactive oxygen speciesbiologyPhysiologyfungiMutantfood and beveragesPlant physiologyPlant Sciencebiology.organism_classificationNitrate reductase01 natural sciencesNitric oxide03 medical and health scienceschemistry.chemical_compoundchemistryBiochemistrybiology.proteinArabidopsis thaliana030304 developmental biology010606 plant biology & botanyPeroxidaseBotrytis cinereaPlant, Cell & Environment
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Antioxidant activity and enzymes inhibitory properties of several extracts from two Moroccan Asteraceae species

2018

Abstract The present work reports investigation on phenolic compounds, antioxidant activity and enzyme inhibitory activities (acetylcholinesterase, butyrylcholinesterase, tyrosinase, α-amylase and α-glucosidase) of different extracts from two Moroccan Asteraceae species; Bubonium imbricatum Cav. and Cladanthus arabicus (L.) Cass. B. imbricatum extracts contained the highest amounts of phenolics and flavonoids, and also exhibited higher antioxidant activity. In this species, the highest total phenolic (1611.13 ± 14.23 μmolGAE/gextract) and flavonoid (376.11 ± 8.22 μmolQE/gextract) contents were observed in aqueous-methanol extract obtained by maceration. Further, UHPLC–MS analysis of C. arab…

0106 biological scienceschemistry.chemical_classificationABTSSettore CHIM/10 - Chimica Degli Alimenti010405 organic chemistryDPPHTyrosinaseFlavonoidAcetylcholinesterase; Bubonium imbricatum Cav.; Butyrylcholinesterase; Cladanthus arabicus (L.) Cass.; Phenolics; Tyrosinase; α-Amylase; α-Glucosidase; Plant SciencePlant Science01 natural sciencesDiosmetin0104 chemical scienceschemistry.chemical_compoundBubonium imbricatum Cav. Cladanthus arabicus (L.) Cass. Phenolics Acetylcholinesterase Butyrylcholinesterase Tyrosinase α-Amylase α-GlucosidasechemistryApigeninMaceration (wine)Food scienceLuteolin010606 plant biology & botany
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Aspartic proteinase from barley grains is related to mammalian lysosomal cathepsin D

1991

Resting barley (Hordeum vulgare L.) grains contain acid-proteinase activity. The corresponding enzyme was purified from grain extracts by affinity chromatography on a pepstatin-Sepharose column. The pH optimum of the affinity-purified enzyme was between 3.5 and 3.9 as measured by hemoglobin hydrolysis and the enzymatic activity was completely inhibited by pepstatin a specific inhibitor of aspartic proteinases (EC 3.4.23). Further purification on a Mono S column followed by activity measurements and sodium dodecyl sulfate-polyacrylamide gel electrophoresis revealed that the affinity-purified enzyme preparation contained two active heterodimeric aspartic proteinases: a larger 48k Da enzyme, c…

0106 biological scienceschemistry.chemical_classificationGel electrophoresis0303 health sciencesProtein subunitCathepsin DPlant ScienceBiology01 natural sciencesMolecular biologyEndopeptidase03 medical and health scienceschemistry.chemical_compoundEnzymechemistryAffinity chromatographyBiochemistryGeneticsHordeum vulgarePepstatin030304 developmental biology010606 plant biology & botanyPlanta
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Drosophila Evolution over Space and Time (DEST) : A New Population Genomics Resource

2021

Drosophila melanogaster is a leading model in population genetics and genomics, and a growing number of whole-genome datasets from natural populations of this species have been published over the last years. A major challenge is the integration of disparate datasets, often generated using different sequencing technologies and bioinformatic pipelines, which hampers our ability to address questions about the evolution of this species. Here we address these issues by developing a bioinformatics pipeline that maps pooled sequencing (Pool-Seq) reads from D. melanogaster to a hologenome consisting of fly and symbiont genomes and estimates allele frequencies using either a heuristic (PoolSNP) or a…

0106 biological sciencesdrosophilia melanogasterdemographyQH301 BiologyadaptationAcademicSubjects/SCI0118001 natural sciencesGene Frequencymedia_common0303 health sciencesEuropean researchbioinformatiikkaGenomics3rd-DASgenomiikkaNew populationResourcesDrosophila melanogaster; SNPs; adaptation; demography; evolution; population genomicsDrosophila melanogasterpopulaatiogenetiikkaChristian ministryCorrigendumSNPsResource (biology)population genomicsEvolutionevoluutioLibrary scienceQH426 GeneticsBiology010603 evolutionary biology03 medical and health sciencesQH301evolutionGeneticsmedia_common.cataloged_instanceAnimalsEuropean unionAdaptationMolecular BiologyQH426Ecology Evolution Behavior and Systematics030304 developmental biologyDemographyAcademicSubjects/SCI01130banaanikärpänenNISGenetics PopulationComputingMethodologies_PATTERNRECOGNITIONResearch councilMCPperimäMetagenomicsPopulation genomics
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Host plant variation plastically impacts different traits of the immune system of a phytophagous insect

2011

Summary 1. Host plant quality affects herbivorous insect performance and consequently their susceptibility to natural enemies. Recently, it has been hypothesized that the immune function of herbivorous insects can be altered by their host plant, thus generating variation in their susceptibility to entomopathogens. Previous studies testing this hypothesis provided contradictory outcomes, mainly as a result of the differences in methodology such as measuring a single-immune parameter rather than considering trade-off-mediated interactions between immune defence systems of the insect. Here, we hypothesized that plant-mediated changes in insect immunity could result from the alteration of physi…

0106 biological sciencesmedia_common.quotation_subjectAntimicrobial peptidesZoologychemical and pharmacologic phenomenaInsectPlant disease resistance010603 evolutionary biology01 natural sciences03 medical and health sciencesImmune systemImmunityBotanyHemolymphEcology Evolution Behavior and Systematics030304 developmental biologymedia_common2. Zero hunger0303 health sciencesEupoecilia ambiguellabiologyfungiProphenoloxidasebiochemical phenomena metabolism and nutritionbiology.organism_classificationbacteriaFunctional Ecology
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Press and bullfighting. The strength of the emotions

2018

Las corridas de toros fueron, tanto por el número asistentes como por la cantidad de festejos que se llevaron a cabo, el primer gran espectáculo de masas que se conoció en España. Enraizado en la fiesta popular, el espectáculo taurino será reconvertido en fiesta nacional a fines del siglo XIX, con el concurso de una prensa que crece en la misma medida que lo hace el sensacionalismo, y el interés de un Estado que utilizará las emociones de los toros para fomentar el amor a la patria. En este trabajo se aborda la dimensión cultural del festejo, su utilización política y el papel fundamental que juega la prensa. The bullfights were the first big spectacle of masses that was known in Spain, so …

0106 biological sciencesspectacleCommunication05 social sciences050801 communication & media studiessensacionalismocultura01 natural sciencesmother country.culturePress0508 media and communicationsPrensapatria.010608 biotechnologyCorridas de torossensationalismespectáculo
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