Search results for "DATABASE"
showing 10 items of 2136 documents
SOUTH AMERICAN COLLABORATION IN SCIENTIFIC PUBLICATIONS ON LEISHMANIASIS: BIBLIOMETRIC ANALYSIS IN SCOPUS (2000-2011)
2014
Objetivos: Evaluar la producción y la red de colaboración de investigación sobre leishmaniasis en Sudamérica. Métodos: Se realizó un estudio bibliométrico usando la base de datos SCOPUS. La unidad de análisis fueron los artículos originales de investigación publicados desde el año 2000 hasta 2011, realizados sobre leishmaniasis y que incluyeron al menos un autor sudamericano. Se obtuvieron para cada artículo: nombre de la revista, idioma, año de publicación, número de autores, instituciones, países y otras variables. Resultados: 3174 artículos fueron publicados, 2.272 de ellos eran artículos originales. Se identificaron 1.160 firmas institucionales diferentes, 58 países y 398 revistas cient…
Prediction of Specific TCR-Peptide Binding From Large Dictionaries of TCR-Peptide Pairs
2019
Abstract The T cell repertoire is composed of T cell receptors (TCR) selected by their cognate MHC-peptides and naive TCR that do not bind known peptides. While the task of distinguishing a peptide-binding TCR from a naive TCR unlikely to bind any peptide can be performed using sequence motifs, distinguishing between TCRs binding different peptides requires more advanced methods. Such a prediction is the key for using TCR repertoires as disease-specific biomarkers. We here used large scale TCR-peptide dictionaries with state-of-the-art natural language processing (NLP) methods to produce ERGO (pEptide tcR matchinG predictiOn), a highly specific classifier to predict which TCR binds to which…
Scribe ergo quæ vidisti et quæ sunt et quæ oportet fieri post hæc
2018
Pasado, presente y futuro se dan cita en el fragmento del Apocalipsis. El pasaje mencionado constituye una invitación a reflexionar sobre el pasado, el presente y el futuro de una persona, de una institución o de una colectividad de cualquier terreno de especialización disciplinar en un momento concreto de su trayectoria en el que se pretende escrutar, valorar las formas cognoscitivas pretéritas y, con ellas, se aspira a redefinir el futuro de la investigación. En esta ocasión me propongo aplicarlo a los estudios relacionados con los testimonios escritos en su pluralidad de manifestaciones medievales.
More is not always better—non-linear effects in crowdfunding
2019
Abstract This research focuses on crowdfunding project features and its relation with the success of this project. The main purpose is to improve probability of success of crowdfunding projects. One can argue that “more is always better” resulting in attempts of daily updates. Contrarily, backers may be weary of numerous updates to work through, indicating a possible wear-out effect, implying the existence of an optimal level of updates. Our preliminary results show that previous research, built upon linear modeling, widely ignores important aspects of the relationship between key variables. We therefore picked six key variables that were previously marked as success drivers in crowdfunding…
Trends in scientific research in Insights into Imaging: a bibliometric review
2019
© The Author(s).
A web-based collection of genotype-phenotype associations in hereditary recurrent fevers from the Eurofever registry
2017
PubMed ID: 29047407
The distributions of protein coding genes within chromatin domains in relation to human disease.
2019
Abstract Background Our understanding of the nuclear chromatin structure has increased hugely during the last years mainly as a consequence of the advances in chromatin conformation capture methods like Hi-C. The unprecedented resolution of genome-wide interaction maps shows functional consequences that extend the initial thought of an efficient DNA packaging mechanism: gene regulation, DNA repair, chromosomal translocations and evolutionary rearrangements seem to be only the peak of the iceberg. One key concept emerging from this research is the topologically associating domains (TADs) whose functional role in gene regulation and their association with disease is not fully untangled. Resul…
Biodiversity of Antarctic echinoids: a comprehensive and interactive database
2005
Eighty-one echinoid species are present south of the Antarctic Convergence, and they represent an important component of the benthic fauna. “Antarctic echinoids” is an interactive database synthesising the results of more than 100 years of Antarctic expeditions, and comprising information about all echinoid species. It includes illustrated keys for determination of the species, and information about their morphology and ecology (text, illustrations and glossary) and their distribution (maps and histograms of bathymetrical distribution); the sources of the information (bibliography, collections and expeditions) are also provided. All these data (taxonomic, morphologic, geographic, bathymetri…
Business Models and Market Entry Mode Choice of Small Software Firms
2007
So far the critical choice of the entry mode for a target country has been examined ignoring the special features of firms. Particularly, the impact of the wide variation of business models of software firms has been ignored. This multi-case study investigates the relation between the business model and the entry mode of eight software firms. The results imply that the product strategy and the service and implementation model of a software firm are closely connected to the entry mode choice, while the distribution model of intangible software products does not seem to have impact on the operation mode. peerReviewed
Preliminary analysis of CH3D from 3250 to 3700 cm(-1)
2006
International audience; The infrared spectrum of CH3D from 3250 to 3700 cm(-1) was studied for the first time to assign transitions involving the nu(2) + nu(3), nu(2) + nu(5), nu(2) + nu(6), nu(3) + 2(nu 6) and 3 nu(6) vibrational states. Line positions and intensities were measured at 0.011 cm(-1) resolution using Fourier transform spectra recorded at Kitt Peak with isotopically enriched samples. Some 2852 line positions (involving over 900 upper state levels) and 874 line intensities were reproduced with RMS values of 0.0009 cm(-1) and 4.6%, respectively. The strongest bands were found to be nu(2) + nu(3) at 3499.7 cm(-1) and nu(2) + nu(6) at 3342.5 cm(-1) with integrated strengths, respe…