Search results for "DDR"
showing 10 items of 108 documents
Riociguat treatment in patients with pulmonary arterial hypertension: Final safety data from the EXPERT registry
2021
OBJECTIVE: The soluble guanylate cyclase stimulator riociguat is approved for the treatment of adult patients with pulmonary arterial hypertension (PAH) and inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension following Phase 3 randomized trials. The EXPosurE Registry RiociguaT in patients with pulmonary hypertension (EXPERT) study was designed to monitor the long-term safety of riociguat in clinical practice. METHODS: EXPERT was an international, multicenter, prospective, uncontrolled, non-interventional cohort study of patients treated with riociguat. Patients were followed for at least 1 year and up to 4 years from enrollment or until 30 days after stopping ri…
Dependability-Based Reliability Analysis in URC Networks: Availability in the Space Domain
2019
Ultra-reliable low latency communication (URLLC), which refers to achieving almost 100% reliability at a certain (satisfactory) level of services and stringent latency, is one of the key requirements for 5G networks. However, most prior studies on reliable communication did not address space domain analysis. Neither were they pursued from a dependability perspective. This paper addresses the ultra-reliable communication (URC) aspect of URLLC and aims at advocating the concept of URC from a dependability perspective in the space domain. We perform in-depth analysis on URC considering both the spatial characteristics of cell deployment and user distributions, as well as service requirements. …
Il fattore personale dell'argomentazione: una prospettiva retorico-antropologica
2014
Dans le cadre d’une approche philosophique et épistémologique, qui privilège le point de vue rhétorique sur l’argumentation et la ligne de pensée Aristote-Vico-Perelman, la thèse essaye d’analyser la construction de la subjectivité dans le discours argumentatif. Je cherche à montrer qu’il est possible de tracer une théorie de l’argumentation dans laquelle subjective n’est pas synonyme de fallacieuse.En général, la thèse analyse le rôle de celui qui parle et de celui qui écoute dans l’argumentation et dans tous les discours. Je vais soutenir est que la dimension personnelle n’est pas un élément qu’il faut supprimer mais, au contraire, un élément essentiel du discours argumentatif.Une approch…
Signs of local adaptation by genetic selection and isolation promoted by extreme temperature and salinity in the Mediterranean seagrass Posidonia oce…
2023
Adaptation to local conditions is known to occur in seagrasses; however, knowledge of the genetic basis underlying this phenomenon remains scarce. Here, we analysed Posidonia oceanica from six sites within and around the Stagnone di Marsala, a semi-enclosed coastal lagoon where salinity and temperature exceed the generally described tolerance thresholds of the species. Sea surface temperatures (SSTs) were measured and plant samples were collected for the assessment of morphology, flowering rate and for screening genome-wide polymorphisms using double digest restriction-site-associated DNA sequencing. Results demonstrated more extreme SSTs and salinity levels inside the lagoon than the outer…
Large-scale genome-wide association studies on a GPU cluster using a CUDA-accelerated PGAS programming model
2015
[Abstract] Detecting epistasis, such as 2-SNP interactions, in genome-wide association studies (GWAS) is an important but time consuming operation. Consequently, GPUs have already been used to accelerate these studies, reducing the runtime for moderately-sized datasets to less than 1 hour. However, single-GPU approaches cannot perform large-scale GWAS in reasonable time. In this work we present multiEpistSearch, a tool to detect epistasis that works on GPU clusters. While CUDA is used for parallelization within each GPU, the workload distribution among GPUs is performed with Unified Parallel C++ (UPC++), a novel extension of C++ that follows the Partitioned Global Address Space (PGAS) model…
Palermo si cura. Pratiche culturali di mutuo soccorso come risposta alle fragilità della città (post)pandemica
2023
In un quadro di riferimento in cui la crisi è globalizzata ma diseguale e in mancanza di un sistema di welfare capace di rispondere alle urgenze dei contesti e dei gruppi sociali più marginalizzati, una risposta ai nuovi bisogni sociali ed individuali è stata offerta da reti solidali e da pratiche di mobilitazione dal basso che svolgono un ruolo di agency territoriale, spesso indipendentemente o in assenza di Istituzioni. Nel contesto palermitano un impegno agito da una pluralità di soggetti culturali già attivi sul territorio, riuniti in un’assemblea pubblica (Palermo si cura), durante il periodo del primo lockdown hanno dato vita ad azioni di mutuo soccorso per rispondere all’emergenza ec…
Meine freie deutsche Jugend und Lagerfeuer: zwei grundverschiedene Erzähltexte über die DDR
2021
The article compares "Meine freie deutsche Jugend", 2003, of Claudia Rusch and "Lagerfeuer", 2003 of Julia Franck. These two texts are partly autobiographical and tell about the life of many young people in East Germany (DDR). The two authors write of traumatic experiences related to the political situation in the DDR which are still alive even today in united Germany in the memory of many Germans.
Information Processing Schemes Based on Monolayer Protected Metallic Nanoclusters
2011
Nanostructures are potentially useful as building blocks to complement future electronics because of their high versatility and packing densities. The fabrication and characterization of particular nanostructures and the use of new theoretical tools to describe their properties are receiving much attention. However, the integration of these individual systems into general schemes that could perform simple tasks is also necessary because modern electronics operation relies on the concerted action of many basic units. We review here new conceptual schemes that can allow information processing with ligand or monolayer protected metallic nanoclusters (MPCs) on the basis of the experimentally de…
Signal processing and frequency-dependent associative memory based on nanoswitches
2008
A signal processing concept based on nanoscale switches whose conductance can be tuned by an external stimulus between two (ON and OFF) states is proposed and analyzed theoretically. The building block of the system is formed by a metal nanoparticle linked to two electrodes by an organic ligand and a molecular switch. When we apply an alternating potential to the system of the same frequency as the periodic variation between the ON and OFF states induced on the switch, the net charge delivered by the system exhibits a sharp resonance. This resonance can be used to process an external signal by selectively extracting the weight of the different harmonics. In addition, a frequency-dependent a…
Promotion of Social Policies – an Investment in the Future: Canada – European Union – Baltic States – Nordic Countries
2009
This volume represents presentations, discussions and research papers in conjunction with the Forum for a Comparative Dialog- an Investment in the Future. The Forum was held in Riga at the University of Latvia on November 6-8, 2008 and was organised by the Centre for European and Transition Studies at the University of Latvia and Capilano University, Canada.