Search results for "DEFICIT"
showing 10 items of 470 documents
The Committee of the Regions: A Springboard for the Citizens
2013
Abstract This study focuses on the relation between the Committee of the Regions (CoR), an advisory institution of the European Union defined as the political assembly of holders of a regional or local electoral mandate serving the cause of European integration, and the democratic deficit, understood as the effective ways of citizens’ participation in the institutional decision making. The work hypothesis is that the CoR, in spite of being mostly unknown to citizens, could be an effective tool for tackling the democratic deficit. Through qualitative interviews and surveys at different levels, the article analyzes the current situation and the potential opportunities of the CoR in its relati…
ASSESSING FAO-56 MODEL TO ESTIMATE TABLE OLIVE WATER CONSUME UNDER SOIL WATER DEFICIT CONDITIONS
2012
Agro-hydrological models can be considered an economic and simple tool to quantify crop water requirements. In the last two decades, agro-hydrological physically based models have been developed to simulate mass and energy exchange processes in the soil-plant-atmosphere system. Although very reliable, due to the high number of required variables, simplified models have been proposed as simple tools to quantify crop water consumes. The main aim of the paper is to assess, for a Sicilian orchard of table olive, the suitability of FAO-56 agro-hydrological model to estimate the crop transpiration under soil water deficit conditions. The model validation is carried out by means of measurements of…
State Budget Constrains for 2013
2013
Abstract The state budget for 2013 is characterized by major constraints generated by the date of payment for the loans committed in the previous period, the high level of the payment arrears from the budget to the real economy, the insurance of the money amount required for the operational programs co-financing and by the acceptance of a lower budget deficit than in 2012, with negative consequences for the economic growth and that doesn’t ensure premises for reducing development gaps between Romania and other EU countries. Decreasing the economy financing by excessive budget deficit reduction is completed this year by the banks financing lines, which is still a handicap for financing the r…
Medical Research and Innovation
2021
This volume is dedicated to multidisciplinary research at the interface between basic biomedicine and clinical practice. This book guides best practice in the diagnosis and therapy while dealing with difficult-to-treat disorders of yet unclear etiology. Chapters address such disorders as granulomatosis with polyangiitis causing autoimmune-related multiorgan inflammation of blood vessels, increasingly widespread allergy to peanuts, occupational exposure to zinc oxide, and immunogenic responses to pneumococcal and influenza vaccination underlying their preventive effectiveness. Other hot issues deal with the proper use of fluid therapy in the perioperative period and a cognitive decline in lu…
Special issue on Trends and challenges of sustainable irrigated agriculture
2014
In the twenty-first century, the shortage of freshwater is one of the most important environmental concerns facing several regions of the world because of the growing demand of increasing population, agricultural intensification, and economic growth. Global climate change will contribute to exacerbate the problem, generating new drought-prone areas and increasing those already characterized by severe aridity. Worldwide it is estimated that, on average, agriculture accounts for 70% of the total water consumption, compared with 10% for domestic consume and the remaining used by industry. Moreover, according to FAO estimates, by 2050 agricultural production has to increase by 60% to satisfy th…
Evidence for shared environmental contributions to attention-deficit/hyperactivity traits. A twin study
2019
Background and objectives: Behavior-genetic analyses have shown that measurements of inattention and hyperactivity-impulsivity are genetically-influenced. In view of limited studies on ADHD (Attention deficit hyperactivity disorder) in Spanish samples, this study aims to explore the genetic architecture of ADHD symptoms; inattention and hyperactivity-impulsivity in a Spanish twin schoolchildren sample. Methods: Participants were 258 pairs of adolescent Spanish twins. Symptoms of ADHD, inattention and hyperactivity-impulsivity were assessed by means of a sub-scale of the Strengths and Difficulties Questionnaire. Univariate twin models, according to sex, were run to assess the heritability of…
Gene Therapy in Rare Respiratory Diseases: What Have We Learned So Far?
2020
Gene therapy is an alternative therapy in many respiratory diseases with genetic origin and currently without curative treatment. After five decades of progress, many different vectors and gene editing tools for genetic engineering are now available. However, we are still a long way from achieving a safe and efficient approach to gene therapy application in clinical practice. Here, we review three of the most common rare respiratory conditions—cystic fibrosis (CF), alpha-1 antitrypsin deficiency (AATD), and primary ciliary dyskinesia (PCD)—alongside attempts to develop genetic treatment for these diseases. Since the 1990s, gene augmentation therapy has been applied in multiple clinical tria…
Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics stud…
2008
Contains fulltext : 71374.pdf (Publisher’s version ) (Closed access) Attention-deficit/hyperactivity disorder (ADHD) is typically characterized by inattention, excessive motor activity, impulsivity, and distractibility. Individuals with ADHD have significant impairment in family and peer relations, academic functioning, and show high co-morbidity with a wide range of psychiatric disorders including oppositional defiant disorder (ODD), conduct disorder (CD), anxiety disorder, depression, substance abuse, and pervasive developmental disorder (PDD). Family studies suggest that ADHD + CD represents a specific subtype of the ADHD disorder with familial risk factors only partly overlapping with t…
Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder
2008
Contains fulltext : 69243.pdf (Publisher’s version ) (Closed access) Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is well established. Seven independent genome-wide linkage scans have been performed to map loci that increase the risk for ADHD. Although significant linkage signals were identified in some of the studies, there has been limited replications between the various independent datasets. The current study gathered the results from all seven of the ADHD linkage scans and performed a Genome Scan Meta Analysis (GSMA) to identify the genomic region with most consistent linkage evidence across the studies. Genome-wide significant linkage (P(S…
No association between two polymorphisms of the serotonin transporter gene and combined type attention deficit hyperactivity disorder.
2008
Contains fulltext : 71091.pdf (Publisher’s version ) (Closed access) Several independent studies have reported association between serotonin transporter gene (SLC6A4) polymorphisms and attention deficit hyperactivity disorder (ADHD). Five studies found evidence for association between the long-allele of a 44-bp insertion/deletion polymorphism (5-HTTLPR) and ADHD. Another two studies corroborated this finding while a further six studies did not find such an association. For a second polymorphism within the gene, a variable number tandem repeat (VNTR) within intron 2, one study demonstrated that the 12/12 genotype was significantly less frequent in ADHD cases compared to controls, while a sec…