Search results for "DELE"
showing 10 items of 631 documents
Transboundary Basins Need More Attention: Anthropogenic Impacts on Land Cover Changes in Aras River Basin, Monitoring and Prediction.
2020
Changes in land cover (LC) can alter the basin hydrology by affecting the evaporation, infiltration, and surface and subsurface flow processes, and ultimately affect river water quantity and quality. This study aimed to monitor and predict the LC composition of a major, transboundary basin contributing to the Caspian Sea, the Aras River Basin (ARB). To this end, four LC maps of ARB corresponding to the years 1984, 2000, 2010, and 2017 were generated using Landsat satellite imagery from Armenia and the Nakhchivan Autonomous Republic. The LC gains and losses, net changes, exchanges, and the spatial trend of changes over 33 years (1984–2017) were investigated. The most important drivers of the…
Obsidian in the Upper Palaeolithic of Iberia
2021
Submitted by André Pereira (andrepereira@letras.ulisboa.pt) on 2021-07-28T13:04:08Z No. of bitstreams: 1 obsidian-in-the-upper-palaeolithic-of-iberia.pdf: 35662679 bytes, checksum: 4c261781e3211c52c02d47cc36e26d98 (MD5) Approved for entry into archive by Manuel Botelheiro Moreno (manuelmoreno@campus.ul.pt) on 2021-07-28T16:31:42Z (GMT) No. of bitstreams: 1 obsidian-in-the-upper-palaeolithic-of-iberia.pdf: 35662679 bytes, checksum: 4c261781e3211c52c02d47cc36e26d98 (MD5) Made available in DSpace on 2021-07-28T16:32:40Z (GMT). No. of bitstreams: 1 obsidian-in-the-upper-palaeolithic-of-iberia.pdf: 35662679 bytes, checksum: 4c261781e3211c52c02d47cc36e26d98 (MD5) Previous issue date: 2021 info:eu…
Refitting lithic laminar fragments to assess Palaeolithic sequences: The case of Cova de les Cendres (Teulada-Moraira, Alicante, Spain)
2020
Abstract The integrity of the different levels that form a sequence and the formation processes of the archaeological deposit must be assessed as a previous step to the construction of behavioural, cultural and evolutionary interpretations. This is especially relevant when dealing with long sequences and cultural evolution constructed on them, as is the case in the research on Upper Palaeolithic. Lithic taphonomy provides insight into these issues and refitting is one of its powerful tools. This approach has been applied to the Aurignacian, Gravettian and Solutrean levels of Cova de les Cendres (Teulada-Moraira, Alicante, Spain), where fracture refits of laminar fragments –including blades,…
Successive Losses of Central Immune Genes Characterize the Gadiformes' Alternate Immunity.
2016
Great genetic variability among teleost immunomes, with gene losses and expansions of central adaptive and innate components, has been discovered through genome sequencing over the last few years. Here, we demonstrate that the innate Myxovirus resistance gene (Mx) is lost from the ancestor of Gadiformes and the closely related Stylephorus chordatus, thus predating the loss of Major Histocompatibility Complex class II (MHCII) in Gadiformes. Although the functional implication of Mx loss is still unknown, we demonstrate that this loss is one of several ancient events appearing in successive order throughout the evolution of teleost immunity. In particular, we find that the loss of Toll-like r…
Evolving by deleting: patterns of molecular evolution of Apple stem pitting virus isolates from Poland
2019
In this study, 267 coat protein gene (CP) sequences from 48 Polish isolates of Apple stem pitting virus (ASPV) were determined. The genetic structure of the virus population was analysed and possible mechanisms of molecular evolution explored. We found evidence of recombination within the ASPV population and the presence of 17 ASPV molecular variants that differ in the length, number and arrangement of deletions in the CP. Population genetic analyses showed significant variation among isolates from pear and apple trees, between isolates from the same host species and, more interestingly, within isolates, supporting the existence of significant levels of variability within individual hosts, …
Development of a low-alcoholic fermented beverage employing cashew apple juice and non-conventional yeasts
2019
Cashew apples are by-products in the production of cashew nuts, which are mostly left to rot in the fields. Cashew apple juice (CAJ), a highly nutritious beverage, can be produced from them. It is rich in sugars and ascorbic acid, but its high polyphenol content makes it bitter and astringent, and therefore difficult to commercialize. The kingdom of fungi contains more than 2000 yeast species, of which only a few species have been studied in relation to their potential to produce aroma compounds. The aim of this research was to develop a new low-alcoholic fermented beverage to valorize cashew apples. For this purpose, a screening was carried out employing non-conventional yeast species and …
Deletion of GLX3 in Candida albicans affects temperature tolerance, biofilm formation and virulence.
2018
Candida albicans is a predominant cause of fungal infections in mucosal tissues as well as life-threatening bloodstream infections in immunocompromised patients. Within the human body, C. albicans is mostly embedded in biofilms, which provides increased resistance to antifungal drugs. The glyoxalase Glx3 is an abundant proteomic component of the biofilm extracellular matrix. Here, we document phenotypic studies of a glx3Δ null mutant concerning its role in biofilm formation, filamentation, antifungal drug resistance, cell wall integrity and virulence. First, consistent with its function as glyoxalase, the glx3 null mutant showed impaired growth on media containing glycerol as the carbon sou…
A new rationale for not picking low hanging fruits: The separation of ownership and control
2019
Recent attempts at explaining the energy-efficiency gap rely on considerations related to organizational and behavioral/cognitive failures. In this paper, we build on the strategic delegation literature to advance a complementary explanation. It is shown that strategic market interaction may encourage business owners to instill a bias against energy efficiency in managerial compensation contracts. Since managers respond to financial incentives, their decisions will reflect this bias, resulting in lack of investment.
Next‐Generation Sequencing‐Based RiboMethSeq Protocol for Analysis of tRNA 2′‐O‐Methylation
2017
Analysis of RNA modifications by traditional physico‐chemical approaches is labor intensive, requires substantial amounts of input material and only allows site‐by‐site measurements. The recent development of qualitative and quantitative approaches based on next‐generation sequencing (NGS) opens new perspectives for the analysis of various cellular RNA species. The Illumina sequencing‐based RiboMethSeq protocol was initially developed and successfully applied for mapping of ribosomal RNA (rRNA) 2′‐O‐methylations. This method also gives excellent results in the quantitative analysis of rRNA modifications in different species and under varying growth condi…
Role of AxyZ Transcriptional Regulator in Overproduction of AxyXY-OprZ Multidrug Efflux System in Achromobacter Species Mutants Selected by Tobramycin
2017
ABSTRACT AxyXY-OprZ is an RND-type efflux system that confers innate aminoglycoside resistance to Achromobacter spp. We investigated here a putative TetR family transcriptional regulator encoded by the axyZ gene located upstream of axyXY-oprZ . An in-frame axyZ gene deletion assay led to increased MICs of antibiotic substrates of the efflux system, including aminoglycosides, cefepime, fluoroquinolones, tetracyclines, and erythromycin, indicating that the product of axyZ negatively regulates expression of axyXY-oprZ . Moreover, we identified an amino acid substitution at position 29 of AxyZ (V29G) in a clinical Achromobacter strain that occurred during the course of chronic respiratory tract…