Search results for "DESIGN"

showing 10 items of 5885 documents

Genome-Wide Association Studies of the PR Interval in African Americans.

2011

The PR interval on the electrocardiogram reflects atrial and atrioventricular nodal conduction time. The PR interval is heritable, provides important information about arrhythmia risk, and has been suggested to differ among human races. Genome-wide association (GWA) studies have identified common genetic determinants of the PR interval in individuals of European and Asian ancestry, but there is a general paucity of GWA studies in individuals of African ancestry. We performed GWA studies in African American individuals from four cohorts (n = 6,247) to identify genetic variants associated with PR interval duration. Genotyping was performed using the Affymetrix 6.0 microarray. Imputation was p…

AdultMaleCancer ResearchMuscle ProteinsSingle-nucleotide polymorphismGenome-wide association studyQH426-470030204 cardiovascular system & hematologyBiologyGenetics and Genomics/Complex TraitsPolymorphism Single NucleotideSodium ChannelsWhite PeopleNAV1.5 Voltage-Gated Sodium ChannelNAV1.8 Voltage-Gated Sodium Channel03 medical and health sciencesElectrocardiography0302 clinical medicineAsian PeopleCardiovascular Disorders/Arrhythmias Electrophysiology and PacingGeneticsSNPHumansCardiac and Cardiovascular SystemsPR intervalInternational HapMap ProjectMyeloid Ecotropic Viral Integration Site 1 ProteinMolecular BiologyGenotypingGenetics (clinical)Ecology Evolution Behavior and Systematics030304 developmental biologyAgedGeneticsHomeodomain Proteins0303 health sciencesArrhythmias CardiacHeart-rate;Atherosclerosis risk; Genetic-analysis; Common variants; Design; Populations; Objectives; Conduction; Disease; TwinsMiddle AgedNeoplasm ProteinsMinor allele frequencyBlack or African AmericanAtrioventricular NodeFemaleT-Box Domain ProteinsImputation (genetics)Research ArticleGenome-Wide Association Study
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Exploring the Enjoyment of Playing Browser Games

2009

Browser games--mostly persistent game worlds that can be used without client software and monetary cost with a Web browser--belong to the understudied digital game types, although they attract large player communities and motivate sustained play. The present work reports findings from an online survey of 8,203 players of a German strategy browser game ("Travian"). Results suggest that multiplayer browser games are enjoyed primarily because of the social relationships involved in game play and the specific time and flexibility characteristics ("easy-in, easy-out"). Competition, in contrast, seems to be less important for browser gamers than for users of other game types. Findings are discuss…

AdultMaleCompetitive BehaviorAdolescentComputer scienceDecision MakingInternet privacycomputer.software_genreChoice BehaviorYoung AdultGame clientGame designGermanyAdaptation PsychologicalHumansInterpersonal RelationsSocial BehaviorVideo game designGame DeveloperVideo gameProblem SolvingApplied PsychologyMotivationNon-cooperative gameGame mechanicsVideo game developmentMultimediaAttitude to Computersbusiness.industryCommunicationComputingMilieux_PERSONALCOMPUTINGGeneral MedicineBehavior AddictiveHuman-Computer InteractionVideo GamesFemalebusinesscomputerSoftwareCyberPsychology & Behavior
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Interrelationships between dental occlusion and plantar arch

2011

The aim of this study was to evaluate the influence of different jaw relationships on the plantar arch during gait.168 subjects, participating in this study, were distributed into two groups: a control (32 males and 52 females, ranging from 18 to 36 years of age) and a Temporomandibular joint disorders group (28 males and 56 females, ranging from 19 to 42 years of age). Five baropodometric variables were evaluated using a baropodometric platform: the mean load pressure on the plantar surface, the total surface of feet, forefoot vs rearfoot loading, forefoot vs rearfoot surface, and the percentage of body weight on each limb. The tests were performed in three dental occlusion conditions: man…

AdultMaleComplementary and Manual TherapyAdolescentDentistryPhysical Therapy Sports Therapy and RehabilitationYoung AdultStatistical significancemedicine.arterymedicineHumansGaitFootbusiness.industryDental occlusionForefootRehabilitationRepeated measures designTemporomandibular Joint DisordersGaitBiomechanical PhenomenaTemporomandibular jointbody regionsStomatognathic systemmedicine.anatomical_structureComplementary and alternative medicinePlantar archFemalebusinessJournal of Bodywork and Movement Therapies
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A computerized system for measuring time perception in human subjects.

1991

We describe an integrated computerized approach to the design, execution and recording of time perception experiments in human subjects. The program is menu driven and runs on an IBM-compatible microcomputer. The method is easy to use, non-obtrusive to the subjects, and flexible enough to allow the investigator to design studies with a wide range of experimental protocols and study parameters. The fact that the results do not depend on proctor bias or subject-proctor interactions are additional advantages. The technique was applied to study the effects of prompt positive feedback on the time perception of normal human subjects who undergo training. The results of this study are reported.

AdultMaleComputer programComputer sciencemedia_common.quotation_subjectMedicine (miscellaneous)CognitionTime perceptionNeuropsychological TestsTest (assessment)FeedbackDesign studiesMicrocomputersPerceptionMicrocomputerTime PerceptionComputerized systemHumansFemaleSimulationSoftwaremedia_commonInternational journal of bio-medical computing
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Exploring the switching of the focus of attention within working memory: A combined event-related potential and behavioral study.

2018

Abstract Working memory enables humans to maintain selected information for cognitive processes and ensures instant access to the memorized contents. Theories suggest that switching the focus of attention between items within working memory realizes the access. This is reflected in object-switching costs in response times when the item for the task processing is to be changed. Another correlate of attentional allocation in working memory is the P3a-component of the human event-related potential. The aim of this study was to demonstrate that switching of attention within working memory is a separable processing step. Participants completed a cued memory-updating task in which they were instr…

AdultMaleComputer science050105 experimental psychologyTask (project management)03 medical and health sciencesP3aExecutive FunctionYoung Adult0302 clinical medicineEvent-related potentialPhysiology (medical)Humans0501 psychology and cognitive sciencesAttentionEvoked PotentialsCued speechCerebral CortexFocus (computing)Working memoryGeneral Neuroscience05 social sciencesCognitionElectroencephalographyEvent-Related Potentials P300Inhibition PsychologicalNeuropsychology and Physiological PsychologyMemory Short-TermPattern Recognition VisualResearch DesignHead startSpace PerceptionFemaleCues030217 neurology & neurosurgeryPsychomotor PerformanceCognitive psychologyInternational journal of psychophysiology : official journal of the International Organization of Psychophysiology
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Using Augmented Reality to Treat Phobias

2005

Virtual reality (VR) is useful for treating several psychological problems, including phobias such as fear of flying, agoraphobia, claustrophobia, and phobia to insects and small animals. We believe that augmented reality (AR) could also be used to treat some psychological disorders. AR and VR share some advantages over traditional treatments. However, AR gives a greater feeling of presence (the sensation of being there) and reality judgment (judging an experience as real) than VR because the environment and the elements the patient uses to interact with the application are real. Moreover, in AR users see their own hands, feet, and so on, whereas VR only simulates this experience. With thes…

AdultMaleComputer sciencemedia_common.quotation_subjectCockroachesVirtual realitycomputer.software_genreFear of flyingUser-Computer InterfaceSensationComputer GraphicsmedicineAnimalsHumansComputer Simulationmedia_commonPhobiasMultimediaSpidersModels Theoreticalmedicine.diseaseComputer Graphics and Computer-Aided DesignTreatment OutcomeMultimediaPhobic DisordersFeelingTherapy Computer-AssistedClaustrophobiaFemaleAugmented realityDesensitization PsychologiccomputerSoftwareCognitive psychologyAgoraphobiaIEEE Computer Graphics and Applications
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Accuracy between virtual surgical planning and actual outcomes in orthognathic surgery by iterative closest point algorithm and color maps: A retrosp…

2018

Background To evaluate the accuracy between actual outcomes and virtual surgical planning (VSP) in orthognathic surgery regarding the use of three-dimensional (3D) surface models for registration using iterative closest point (ICP) algorithm and generated color maps. Material and Methods Construction of planning and postoperative 3D models in STL files format (M0 and M1, respectively) from CBCT of 25 subjects who had been submitted to bimaxillary orthognathic surgery was performed. M0 and M1 were sent to Geomagic software in semi-automatic alignment surface mesh order of M0 and M1 for registration using ICP algorithm to calculate mean deviation (MD, MD+, MD-, SD) and root mean square (RMS –…

AdultMaleComputer sciencemedicine.medical_treatmentOrthognathic surgery3d modelMandibleNoseSurgical planningPatient Care PlanningRoot mean square03 medical and health sciencesImaging Three-Dimensional0302 clinical medicineSoftwareMaxillamedicineHumansGeneral DentistryRetrospective StudiesReproducibilityOrthognathic Surgical Proceduresbusiness.industryResearchOrthognathic SurgeryReproducibility of ResultsIterative closest pointRetrospective cohort study030206 dentistryCone-Beam Computed Tomography:CIENCIAS MÉDICAS [UNESCO]Treatment OutcomeSurgery Computer-AssistedOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASComputer-Aided DesignFemaleSurgeryOral SurgerybusinessAlgorithmAlgorithmsMedicina Oral Patología Oral y Cirugia Bucal
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‘Ain't nothin' like the real thing’. Motivation and study processes on a work-based project course in information systems design

2007

Background. Advocates of the project method claim that project-based learning inspires student learning. However, it has been claimed that project-based learning environments demand quite a bit of self-regulation on the part of the learner. Aims. Consequently, it was tested whether students scoring low in self-regulation of learning experienced ‘friction’, an incompatibility between student self-regulation and the demands posed by the learning environment. This would be manifest in cognitive processing and motivation. Samples. The target group consisted of 58 mainly third-year Finnish university students taking a mandatory project course in information systems design. During the project cou…

AdultMaleCooperative learningUniversitiesHigher educationTeaching method050109 social psychologyEducationSoftware DesignSurveys and QuestionnairesComputingMilieux_COMPUTERSANDEDUCATIONDevelopmental and Educational PsychologyMathematics educationInformation systemHumansLearningta5160501 psychology and cognitive sciencesStudentsGrading (education)Motivationbusiness.industry4. EducationLearning environment05 social sciences050301 educationCollaborative learningSocial Control InformalFemaleProject methodPsychologybusiness0503 educationSocial psychologyInformation SystemsBritish Journal of Educational Psychology
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Clinical studies on the appearance of natural anterior teeth in young and old adults

2004

Objectives:  To evaluate the typical appearance of natural anterior teeth in young and elderly people and to develop guidelines for the natural appearance of dentures. Design:  Clinical examination and photography. Inclusion criteria were a dental state with natural anterior teeth and no more than two crowns. Subjects:  A study group (SG) consisting of 64 patients ranging in age from 60 to 86 years (67.3 ± 5.8) and a control group (CG) composed of 64 dental students aged 21–33 years (25.8 ± 2.4). Setting:  Dental schools of the Johannes-Gutenberg-University Mainz and the University of Leipzig. Results:  Most participants were content with the appearance of their own natural teeth. With rela…

AdultMaleCuspidmedicine.medical_treatmentColorDentistryMandibleEsthetics DentalDental Archstomatognathic systemMaxillamedicineHumansElderly peopleDenture DesignGeneral DentistryAnterior teethAgedAged 80 and overOrthodonticsbusiness.industryAnterior archMiddle AgedIncisorTooth Abrasionstomatognathic diseasesTooth DiscolorationFemaleGeriatrics and GerontologyDenturesbusinessAttitude to HealthGerodontology
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Marginal soft tissue stability around conical abutments inserted with the one abutment-one time protocol after 5 years of prosthetic loading

2018

BACKGROUND Soft tissue stability is crucial to obtain and maintain optimal esthetic results. PURPOSE This study aimed to investigate, over 5 years, the soft tissue response using a conical abutment together with the "one-abutment one-time" (OA-OT) protocol in the restoration of implants inserted in the anterior esthetic area. MATERIAL AND METHODS From January 2011 to January 2012, all consecutive patients requiring an implant n the maxillary area between canines were enrolled. After submerged healing and osseointegration, a definitive abutment with a provisional crown was inserted. After 1 month, the definitive crown was delivered (Tdef). Analog impressions were taken before tooth extractio…

AdultMaleCuspidmedicine.medical_treatmentPlatform switchingAbutmentGingivaDental Abutmentsconical abutments long-term one-abutment-one-time platform switching soft tissue soft tissue biotypeOsseointegrationCrown (dentistry)03 medical and health sciences0302 clinical medicineDental Implants Single-ToothMaxillaMedicineHumansGeneral DentistryOrthodonticslong-termbusiness.industryplatform switchingDental Implantation EndosseousSoft tissueMean ageDental Implant-Abutment Design030206 dentistryConical surfacesoft tissue biotypeconical abutments030220 oncology & carcinogenesisFemaleImplantDental Prosthesis Implant-SupportedOral Surgeryone-abutment-one-timebusinesssoft tissueFollow-Up Studies
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