Search results for "DF"

showing 10 items of 1699 documents

Insight into the Mechanism of Action of Marine Cytotoxic Thiazinoquinones

2017

The electrochemical response of four natural cytotoxic thiazinoquinones isolated from the Aplidium species was studied using conventional solution-phase and solid-state techniques, based on the voltammetry of immobilized particles methodology. The interaction with O-2 and electrochemically generated reactive oxygen species (ROS) was electrochemically monitored. At the same time, a molecular modeling study including density functional theory (DFT) calculations was performed in order to analyze the conformational and electronic properties of the natural thiazinoquinones, as well as those of their reduced intermediates. The obtained electrochemical and computational results were analyzed and c…

Aquatic OrganismsMolecular modelStereochemistryBioactive natural products; Cytotoxic activity; DFT calculations; Electrochemistry; Reactive radical species; Thiazinoquinones; Animals; Electrochemistry; Quinones; Reactive Oxygen Species; Aquatic Organisms; Urochordata; Drug Discovery3003 Pharmaceutical ScienceThiazinoquinoneDFT calculationPharmaceutical Science02 engineering and technologyDFT calculationsElectrochemistry01 natural sciencesArticleAplidiumbioactive natural products; thiazinoquinones; electrochemistry; DFT calculations; reactive radical species; cytotoxic activityComputational chemistryDrug DiscoverymedicineAnimalsCytotoxic T cellUrochordataBioactive natural productlcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Voltammetrycytotoxic activitychemistry.chemical_classificationReactive oxygen speciesbiology010405 organic chemistryDrug Discovery3003 Pharmaceutical ScienceQuinonesReactive radical specie021001 nanoscience & nanotechnologybiology.organism_classification0104 chemical scienceslcsh:Biology (General)electrochemistryMechanism of actionchemistryreactive radical speciesbioactive natural productsthiazinoquinonesDensity functional theorymedicine.symptomReactive Oxygen Species0210 nano-technologyMarine Drugs
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Influence of a specific aquatic adapted physical activity in a child with Autism Spectrum Disorders: A case study

2019

Aquatic environment offers an exciting and motivating place for children and aquatic exercise programs provide an appropriate setting for early educational interventions in individuals with autism spectrum disorders (ASD). The purpose of this study was to examine the effects of a specific Multi-systemic Aquatic Therapy (CI-MAT) on gross motor and adaptive skills in a child with ASD. The study was divided into three phases: baseline, 12-week CI-MAT program and Post-Test. Child was administered a battery of tests incorporating anthropometric measurements, gross motor development test (TGM test), Vineland Adaptive Behavior Scales (VABS) and Psychoeducational Profile (PEP-3) before and after a …

Aquatic TherapySettore M-PSI/04 - Psicologia Dello Sviluppo E Psicologia Dell'EducazioneSettore M-EDF/02 - Metodi E Didattiche Delle Attivita' SportiveAutism Spectrum DisorderHealth.Settore M-EDF/01 - Metodi E Didattiche Delle Attivita' MotorieSwimmingSport
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A novel thermodynamic approach for the complexation study of toxic metal cations by a landfill leachate

2018

Landfill leachates can contaminate nearby aquifers. The hazards deriving from this contamination also depend on the chemical speciation of various contaminants. A novel approach is proposed here to face this problem from a chemical thermodynamics point of view. The complexing ability of the soluble fraction of a landfill leachate (collected from Bellolampo, Palermo, Italy) towards Pb2+, Cd2+ and Cu2+ has been investigated at T = 298.15 K in NaClaq at I = 0.1 mol dm−3. The soluble fraction of the landfill leachate was first characterized by different analytical techniques. Then, its acid–base properties were studied by ISE-H+ potentiometric titrations and modelled by the so-called diprotic-l…

Aqueous solutionChemistryPotentiometric titrationInorganic chemistry02 engineering and technologyGeneral Chemistry010501 environmental sciences021001 nanoscience & nanotechnology01 natural sciencesCatalysisMetalAnodic stripping voltammetryLandfill leachate sequestering ability complexation toxic metalsChemical thermodynamicsSequestrantvisual_artMaterials Chemistryvisual_art.visual_art_mediumTitrationSettore CHIM/01 - Chimica AnaliticaLeachate0210 nano-technology0105 earth and related environmental sciences
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Compositional reference for the documented Archaic production of indigenous matt-painted pottery at Entella (Western Sicily)

2015

This contribution is focused on a specific class of indigenous Archaic pottery (sixth and fifth century BC) with matt-painted geometric decoration that was recovered in large quantities in the excavations at Entella, an indigenous site located in western Sicily. The site of Entella was strategically considerable in this part of Sicily, controlling the north-south routes running along the river Belice. Kiln structures were attested at Entella that, until today, it is the only Archaic site in the area with an unmistakable evidence of production of fine pottery. The present research is aimed at yielding a complete petrographic and chemical characterization of the table ware produced at Entella…

ArcheologyHistoryPetrography020101 civil engineeringMatt-painted table ware02 engineering and technologyAncient history010502 geochemistry & geophysics01 natural sciencesArchaeometryIndigenous0201 civil engineeringArchaeological sciencePetrographyCeramic productionTable (landform)EntellaSicilySettore GEO/09 -Georis. Miner.e Appl.Mineral.-Petrogr. per l'Ambi.ed i B.Cult.0105 earth and related environmental sciencesArchaic ageExcavationArchaeologyChemistryAnthropologyPotteryArchaeological and Anthropological Sciences
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Subglacial bed deformation and dynamics of the Apriķi glacial tongue, W Latvia

2011

Saks, T., Kalvans, A. & Zelcs, V. 2012 (January): Subglacial bed deformation and dynamics of the Apriķi glacial tongue, W Latvia. Boreas, Vol. 41, pp. 124–140. 10.1111/j.1502-3885.2011.00222.x. ISSN 0300-9483. We evaluate the glacial dynamics and subglacial processes of the Apriķi glacial tongue in western Latvia during the Northern Lithuanian (Linkuva) oscillation of the last Scandinavian glaciation. The spatial arrangement of glacial bedforms and deformation structures are used to reconstruct the ice dynamics in the study area. The relationship between geological structures at the glacier bed and the spatial distribution of drumlins and glacigenic diapirs, on the one hand, and the permeab…

Archeologygeographygeography.geographical_feature_categoryBedformOldest DryasBedrockDrumlinGeologyGlacierDiapirFast iceGlacial periodGeomorphologyEcology Evolution Behavior and SystematicsGeologyBoreas
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Efficient pruning of multilayer perceptrons using a fuzzy sigmoid activation function

2006

This Letter presents a simple and powerful pruning method for multilayer feed forward neural networks based on the fuzzy sigmoid activation function presented in [E. Soria, J. Martin, G. Camps, A. Serrano, J. Calpe, L. Gomez, A low-complexity fuzzy activation function for artificial neural networks, IEEE Trans. Neural Networks 14(6) (2003) 1576-1579]. Successful performance is obtained in standard function approximation and channel equalization problems. Pruning allows to reduce network complexity considerably, achieving a similar performance to that obtained by unpruned networks.

Artificial neural networkComputer sciencebusiness.industryTime delay neural networkCognitive NeuroscienceActivation functionRectifier (neural networks)PerceptronFuzzy logicComputer Science ApplicationsArtificial IntelligenceMultilayer perceptronFeedforward neural networkPruning (decision trees)Artificial intelligenceTypes of artificial neural networksbusinessNeurocomputing
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A COMPARATIVE STUDY OF PHENOMENOLOGICAL MODELS OF MR BRAKE BASED ON NEURAL NETWORKS APPROACH

2013

In this paper a full-scale commercially available magnetorheological (MR) brake installed in a semi-active suspension (SAS) system is modeled and simulated. Two well-known phenomenological hysteresis models are explored: Bouc–Wen and Dahl ones. In particular, influence of their parameters on the response is evaluated and assessed. The next step is to introduce the artificial neural networks and discuss their application in the field of systems identification. Subsequently, two feedforward neural networks are created and trained to estimate parameters characterizing each of the MR damper models described. The semi-active suspension (SAS) system equipped with a MR brake is described and the …

Artificial neural networkMathematical modelComputer scienceControl theoryApplied MathematicsSignal ProcessingBrakeReference data (financial markets)Magnetorheological fluidExperimental dataFeedforward neural networkInformation SystemsDamperInternational Journal of Wavelets, Multiresolution and Information Processing
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Optimal Pruned K-Nearest Neighbors: OP-KNN Application to Financial Modeling

2008

The paper proposes a methodology called OP-KNN, which builds a one hidden-layer feed forward neural network, using nearest neighbors neurons with extremely small computational time. The main strategy is to select the most relevant variables beforehand, then to build the model using KNN kernels. Multi-response sparse regression (MRSR) is used as the second step in order to rank each k-th nearest neighbor and finally as a third step leave-one-out estimation is used to select the number of neighbors and to estimate the generalization performances. This new methodology is tested on a toy example and is applied to financial modeling.

Artificial neural networkRank (linear algebra)GeneralizationComputer scienceKernel (statistics)Financial modelingFeedforward neural networkRegression analysisData miningcomputer.software_genrecomputerk-nearest neighbors algorithm2008 Eighth International Conference on Hybrid Intelligent Systems
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A Multi-layer Feed Forward Neural Network Approach for Diagnosing Diabetes

2018

Diabetes is one of the worlds major health problems according to the World Health Organization. Recent surveys indicate that there is an increase in the number of diabetic patients resulting in an increase in serious complications such as heart attacks and deaths. Early diagnosis of diabetes, particularly of type 2 diabetes, is critical since it is vital for patients to get insulin treatments. However, diagnoses could be difficult especially in areas with few medical doctors. It is, therefore, a need for practical methods for the public for early detection and prevention with minimal intervention from medical professionals. A promising method for automated diagnosis is the use of artificial…

Artificial neural networkbusiness.industryComputer science02 engineering and technologyType 2 diabetes030204 cardiovascular system & hematologymedicine.diseaseMachine learningcomputer.software_genreMissing dataData set03 medical and health sciences0302 clinical medicineIntervention (counseling)Diabetes mellitus0202 electrical engineering electronic engineering information engineeringmedicineFeedforward neural network020201 artificial intelligence & image processingArtificial intelligenceMedical diagnosisbusinesscomputer2018 11th International Conference on Developments in eSystems Engineering (DeSE)
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Efficient MLP Digital Implementation on FPGA

2005

The efficiency and the accuracy of a digital feed-forward neural networks must be optimized to obtain both high classification rate and minimum area on chip. In this paper an efficient MLP digital implementation. The key features of the hardware implementation are the virtual neuron based architecture and the use of the sinusoidal activation function for the hidden layer. The effectiveness of the proposed solutions has been evaluated developing different FPGA based neural prototypes for the High Energy Physics domain and the automatic Road Sign Recognition domain. The use of the sinusoidal activation function decreases hardware resource employment of about 32% when compared with the standar…

Artificial neural networkbusiness.industryComputer scienceActivation functionField programmable gate arrays (FPGA)Sigmoid functionartificial neuralMachine learningcomputer.software_genreTransfer functionDomain (software engineering)Feedforward neural networkSystem on a chipArtificial intelligencebusinessField-programmable gate arraycomputerComputer hardwareNeural networks
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