Search results for "DIAGNOSTICS"
showing 10 items of 197 documents
Clinical evaluation of melanomas and common nevi by spectral imaging
2012
A clinical trial on multi-spectral imaging of malignant and non-malignant skin pathologies comprising 17 melanomas and 65 pigmented common nevi was performed. Optical density data of skin pathologies were obtained in the spectral range 450-950 nm using the multispectral camera Nuance EX. An image parameter and maps capable of distinguishing melanoma from pigmented nevi were proposed. The diagnostic criterion is based on skin optical density differences at three fixed wavelengths: 540nm, 650nm and 950nm. The sensitivity and specificity of this method were estimated to be 94% and 89%, respectively. The proposed methodology and potential clinical applications are discussed.
Therapeutic and diagnostic applications of nanoparticles.
2011
Nanoparticles are sphere-like biocompatible materials made of inert silica, metal or crystals of a few nanometers in size. They are emerging as a novel class of therapeutics for cancer treatment. Being more selective and specific toward their targets, nanoparticles have the ability to enhance the anticancer effects and to simultaneously reduce systemic toxicity compared with conventional therapeutics. Furthermore, they offer the potential to overcome drug resistance leading to higher intracellular drug accumulation. Nowadays, nanotechnologies are applied to molecular diagnostics and incorporated in cutting-edge molecular diagnostic methods, such as DNA and protein microarray biochips. Nanot…
PROMINENCE PLASMA DIAGNOSTICS THROUGH EXTREME-ULTRAVIOLET ABSORPTION
2013
In this paper we introduce a new diagnostic technique that uses prominence EUV and UV absorption to determine the prominence plasma electron temperature and column emission measure, as well as He/H relative abundance; if a realistic assumption on the geometry of the absorbing plasma can be made, this technique can also yield the absorbing plasma electron density. This technique capitalizes on the absorption properties of Hydrogen and Helium at different wavelength ranges and temperature regimes. Several cases where this technique can be successfully applied are described. This technique works best when prominence plasmas are hotter than 15,000 K and thus it is ideally suited for rapidly hea…
Looking through the photoionisation wake: Vela X−1 at φorb ≈ 0.75 with Chandra/HETG
2021
Context. The supergiant X-ray binary Vela X−1 represents one of the best astrophysical sources to investigate the wind environment of an O/B star irradiated by an accreting neutron star. Previous studies and hydrodynamic simulations of the system have revealed a clumpy environment and the presence of two wakes: an accretion wake surrounding the compact object and a photoionisation wake trailing it along the orbit. Aims. Our goal is to conduct, for the first time, high-resolution spectroscopy on Chandra/HETGS data at the orbital phase φorb ≈ 0.75, when the line of sight is crossing the photoionisation wake. We aim to conduct plasma diagnostics, inferring the structure and the geometry of the…
Position-sensitive ion detection in precision Penning trap mass spectrometry
2009
A commercial, position-sensitive ion detector was used for the first time for the time-of-flight ion-cyclotron resonance detection technique in Penning trap mass spectrometry. In this work, the characteristics of the detector and its implementation in a Penning trap mass spectrometer will be presented. In addition, simulations and experimental studies concerning the observation of ions ejected from a Penning trap are described. This will allow for a precise monitoring of the state of ion motion in the trap.
A microcalorimeter spectrometer for the investigation of laboratory plasmas
2002
We describe a cryostat and 2-stage ADR specifically designed for making measurements at the NIST EBIT (Electron Beam Ion Trap) facility. The design is compact and consists of a single helium bath with two vapor-cooled shields. The 2-stage ADR has two separate magnets and two heat switches. The interface between the EBIT and microcalorimeter array will also be described.
Plasma instability in the afterglow of electron cyclotron resonance discharge sustained in a mirror trap
2012
The work presented in this article is devoted to time-resolved diagnostics of non-linear effects observed during the afterglow plasma decay of a 14 GHz electron cyclotron resonance ion source operated in pulsed mode. Plasma instabilities that cause perturbations of the extracted ion current during the decay were observed and studied. It is shown that these perturbations are associated with precipitation of high energy electrons along the magnetic field lines and strong bursts of bremsstrahlung emission. The effect of ion source settings on the onset of the observed instabilities was investigated. Based on the experimental data and estimated plasma properties, it is assumed that the instabil…
Experimental evidence of E × B plasma rotation in a 2.45 GHz hydrogen discharge
2015
An experimental observation of a rotating plasma structure in a 2.45 GHz microwave-driven hydrogen discharge is reported. The rotation is presumably produced by E × B drift. The formation of the rotating plasma structure is sensitive to the strength of the off-resonance static magnetic field. The rotation frequency is on the order of 10 kHz and is affected by the neutral gas pressure and applied microwave power.
Experimental Stark-broadening studies of the NI multiplet $\mathsf{(^{1}D) 3s^{2}D - (^{1}D)3p^{2}P^{o}}$ at 7904.5 �
2004
Experimental Stark-broadening studies of the NI multiplet $(^{1}{\rm D})3s$ $^{2}{\rm D} - (^{1}{\rm D})3p$ $^{2}{\rm P}^{\rm o}$ are reported. Line shape measurements were performed using a wall-stabilized arc operated at atmospheric pressure in helium with small amounts of nitrogen and hydrogen. The radiation of the plasma emitted from nearly homogeneous plasma layers in end-on direction was measured using a grating spectrometer equipped with a charge-coupled device (CCD) detector. The arc current was varied from 35 to 50 A in order to obtain different plasma conditions (electron densities and temperatures). The so-called j(x) profiles of Griem, convoluted with the corresponding Doppler a…
Lifetime Studies in Traps
2009
A knowledge of the radiative lifetimes of excited atomic states is of wide interest, not only in the detailed understanding of intrinsic atomic structure and dynamics but also in the fields of plasma diagnostics and astrophysics. The transition rates of intercombination and electric-dipole forbidden lines are of particular importance, since their low transition probability gives them long optical depths in plasmas and astrophysical environments.