Search results for "DIAGNOSTICS"

showing 10 items of 197 documents

CRISPR-Cas12a-Based Detection of SARS-CoV-2 Harboring the E484K Mutation

2021

The novel respiratory virus SARS-CoV-2 is rapidly evolving across the world with the potential of increasing its transmission and the induced disease. Here, we applied the CRISPR-Cas12a system to detect, without the need of sequencing, SARS-CoV-2 genomes harboring the E484K mutation, first identified in the Beta variant and catalogued as an escape mutation. The E484K mutation creates a canonical protospacer adjacent motif for Cas12a recognition in the resulting DNA amplicon, which was exploited to obtain a differential readout. We analyzed a series of fecal samples from hospitalized patients in Valencia (Spain), finding one infection with SARS-CoV-2 harboring the E484K mutation, which was t…

PolymersBiomedical EngineeringBiosensing TechniquesBiologyBiochemistry Genetics and Molecular Biology (miscellaneous)Genomechemistry.chemical_compoundCOVID-19 TestingPeptide LibraryTechnical NoteCRISPRCRISPR diagnosticsHumansGeneticsvirus evolutionSARS-CoV-2Epidemiological surveillanceepidemiological surveillanceCOVID-19General MedicineDNAAmpliconSurface Plasmon ResonanceVirus evolutionProtospacer adjacent motifHEK293 CellschemistryGenetic TechniquesSpainViral evolutionImmunoglobulin GMutation (genetic algorithm)DNA ViralMutationRespiratory virusCRISPR-Cas SystemsDNAACS Synthetic Biology
researchProduct

Introduction and Psychometric Validation of the Resilience and Strain Questionnaire (ResQ-Care)— A Scale on the Ratio of Informal Caregivers' Resilie…

2021

Background: Informal caregivers are a particularly vulnerable population at risk for adverse health outcomes. Likewise, there are many scales available assessing individual caregiver burden and stress. Recently, resilience in caregivers gained increasing interest and scales started to assess resilience factors as well. Drawing on a homeostatic model, we developed a scale assessing both caregivers' stress and resilience factors. We propose four scales, two covering stress and two covering resilience factors, in addition to a sociodemographic basic scale. Based on the stress:resilience ratio, the individual risk of adverse health outcomes and suggestions for interventions can be derived.Metho…

Psychiatrystress awarenessDiscriminant validityRC435-571Perceived Stress ScalehealthCaregiver burdenExploratory factor analysisPsychiatry and Mental healthcounselingCronbach's alphapreventionScale (social sciences)homeostasisdiagnosticsGeriatric Depression ScalePsychologyResilience (network)Original ResearchClinical psychologyFrontiers in Psychiatry
researchProduct

Stark effect in some lines of neutral bromine

2002

Abstract This work presents experimental results of profile parameters for prominent lines of neutral bromine, for which serious discrepancies between experimental values of different authors as well as between experimental and calculated values were observed. The observed discrepancies between shock tube and earlier arc experiments are very large. Our results of profile parameters, obtained also in a wall-stabilized arc, show acceptable agreement with the earlier arc measurements. It is obvious, that the shock tube experimental result is out of the range of acceptable inaccuracy and should be remeasured. The theoretical calculations based on different assumptions give also strongly diverge…

RadiationBromineArgonMaterials sciencechemistry.chemical_elementAtomic and Molecular Physics and OpticsSpectral lineArc (geometry)symbols.namesakeStark effectchemistrysymbolsPlasma diagnosticsAtomic physicsShock tubeSpectroscopyLine (formation)Journal of Quantitative Spectroscopy and Radiative Transfer
researchProduct

Determination of gas temperature of high-frequency low-temperature electrodeless plasma using molecular spectra of hydrogen and hydroxyl-radical

2012

Abstract In this study we determine gas temperature of He+H 2 , Ar+H 2 and Ne+H 2 high frequency electrodeless lamps using intensity distribution in rotational spectra of hydrogen molecule and hydroxyl radical. The measurement results show that OH rotational spectra can be successfully used for estimation of gas temperature of the high-frequency electrodeless lamps at very small amounts of hydrogen present in plasma. The analysis of the measurement results leads to the conclusion that in “pure” plasma the applied energy is used to heat plasma, while for the plasma with hydrogen addition the energy is used in chemical reactions.

RadiationMaterials scienceHydrogenAnalytical chemistrychemistry.chemical_elementRotational temperaturePlasmaChemical reactionAtomic and Molecular Physics and OpticsSpectral linechemistry.chemical_compoundchemistryHydroxyl radicalPlasma diagnosticsAtomic physicsSpectroscopyIntensity (heat transfer)Journal of Quantitative Spectroscopy and Radiative Transfer
researchProduct

Optical Plasma Diagnostics During Reactive Magnetron Sputtering

2008

Reactive magnetronMaterials science[SPI] Engineering Sciences [physics]Sputteringbusiness.industryOptoelectronicsPlasma diagnosticsOptical emission spectroscopyHigh-power impulse magnetron sputteringbusinessGlow discharge mass spectroscopy
researchProduct

Rotational CARS thermometry at high temperature (1800 K) and high pressure (0.1-1.55 MPa)

2007

International audience; Dual-broadband rotational CARS (DB-RCARS) thermometry has been investigated at high temperature and high pressure. Single-shot measurements were performed at 1800 K, in air and nitrogen at pressures up to 1.55 MPa and in oxygen at pressures up to 0.5 MPa. For all conditions, the resonant signal contribution to the spectra clearly dominated over the non-resonant one, implying the high potential for DB-RCARS for temperature and concentration measurements also at the high temperatures and pressures used in the present investigation. The relative standard deviation was generally similar to 2% for single-shot data at pressures from 0.5 to 1.55 MPa. At the investigated tem…

Relative standard deviationAnalytical chemistrychemistry.chemical_element02 engineering and technology7. Clean energy01 natural sciencesOxygenSpectral lineStandard deviation010309 opticssymbols.namesakecombustion diagnostics0103 physical sciencesGeneral Materials Sciencerotational CARSSpectroscopy[PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics][ PHYS.PHYS.PHYS-OPTICS ] Physics [physics]/Physics [physics]/Optics [physics.optics]Chemistry021001 nanoscience & nanotechnologyNitrogengas-phase thermometryHigh pressureExcited statesymbols0210 nano-technologyRaman spectroscopy
researchProduct

Verifiche Diagnostiche nell'ex Chiesa Madre di Santa Margherita di Belice

2011

La relazione presenta in modo dettagliato gli esiti della seconda campagna di indagini diagnostiche, svolta nella fabbrica architettonica a cantiere di restauro in corso d'opera. L'obiettivo delle valutazioni non distruttive e minimamente invasive è valutare la corretta esecuzione degli interventi attraverso il confronto tra la diagnosi preliminare e quella post-intervento. The report presents in detail the results of the second campaign of diagnostic investigations, carried out in the architectural restoration site. The goal of minimally invasive and non-destructive evaluation is to assess the proper execution of consolidation through the comparison between the preliminary and post-interve…

Restauro diagnostica cantiere termografia radar ultrasuoni endoscopia consolidamentoSettore ICAR/19 - RestauroRestoration diagnostics thermography radar ultrasound endoscopy consolidation
researchProduct

Sistema integrato di metodiche diagnostiche per il restauro della chiesa di Sant’Anna La Misericordia a Palermo

2010

E' mostrata l'applicazione di un sistema combinato di letture strumentali finalizzate all'ottenimento di una diagnosi attraverso un approccio dall'elevato rigore scientifico. Le analisi strumentali sono svolte nella chiesa di Sant'Anna a Palermo. The graphs show the application of a combined system of instrumental readings aimed to obtain a diagnosis through a high scientific and rigorous approach. The instrumental tests are executed in the St. Anne church in Palermo.

Restauro diagnostica termografia radar trapano resistograficoSettore ICAR/19 - RestauroRestoration diagnostics thermography radar survey resistograph
researchProduct

Finte Pietre. Architettura dell'apparire e conservazione dei valori culturali

2012

Il volume presenta gli esiti di una ricerca incentrata sulla conoscenza delle finiture architettoniche di pietra artificiale, con particolare attenzione agli intonaci brevettati nel 1901 dai fratelli Li Vigni. Le attività di studio sono condotte attraverso la ricognizione dei documenti conservati presso l’Archivio Centrale dello Stato a Roma, e compiono una rigorosa selezione e analisi dei brevetti con l’obiettivo di tracciare il percorso evolutivo dei metodi d’intonacatura ed evidenziare i legami che s’instaurano tra le ricerche in corso nei diversi paesi. Nel XIX secolo i ricercatori di molte nazionalità avviano una selezione critica delle ricette tramandate dal passato e perfezionano pro…

Restauro pietra artificiale superficie intonaco malta calce sabbia cemento diagnosticaRestauration pierre artificielle surface plâtre mortier chaux sable ciment diagnosticSettore ICAR/19 - RestauroRestoration artificial stone surface plaster mortar lime sable cement diagnostics
researchProduct

DIAGNOSIS FOR ARCHITECTURAL CONSERVATION. A synthetic report of a campaign of non-destructive and minimally invasive diagnostic tests performed in th…

2014

The paper presents the results of a campaign of non-destructive and minimally invasive tests that were conducted in the church of Santa Maria delle Stelle in Comiso (Ragusa, Sicily), which is the larger church in the Diocese of Ragusa. It includes a summary of the reflections that arose during the preliminary surveys and instrumental tests, and reasons that supported the choice of investigations to be performed and methods to be specifically applied for the consolidation of the architectural structures and plaster layers.

Restoration conservation monument diagnosticsSettore ICAR/19 - Restauro
researchProduct