Search results for "DIF"
showing 10 items of 16936 documents
Organizational transformation from tailored software production to international Modified-Off-The-Shelf software business model
2002
Digital Content Consumption : A Finnish-Austrian Cross-Country Analysis
2019
Online content consumption behavior has significantly changed. In particular, the growing success of legal media service providers such as Youtube, Netflix, or Spotify, has led to new modes of consumption. Research, however, still focuses predominately on illegal streaming and downloading behavior and its impact on media companies' commercial success. In order to paint a more comprehensive picture, we report on a cross-country study conducted in Austria and Finland, which explored digital content consumption habits and sources, young adults' attitudes towards illegal sources, and the importance of price, legality, ease of use as well as ease of access, and its influence on people's consumpt…
Improving the game with user generated content : an overview of Skyrim mod users
2017
Käyttäjien luoma sisältö on merkittävä ja kasvava osa videopelikulttuuria. Tämä tutkielma tarkastelee fanien luomia ohjelmistomuokkauksia, modeja, joilla muutetaan tai lisätään sisältöä peleissä. Tutkielman tavoitteena on selvittää modien käyttäjien motivaatiota sekä tekijöitä, jotka vaikuttavat modien käyttämisen yleisyyteen. Vaikka modeja on tutkittu akateemisesti, on tutkimus modien käyttäjien näkökulmasta jäänyt hyvin vähäiseksi. Tässä tutkimuksessa tarkasteltiin suositun roolipelin, Skyrimin saatavilla olevia modeja. Empiirinen osuus toteutettiin kuvailevana kyselytutkimuksena, joka kohdistettiin erääseen suureen Skyrim-modiyhteisöön. Kyselyssä selvitettiin modien käyttöön liittyviä ta…
Muzikālās rotaļas skaņu diferencēšanai 2 - 3 gadus veciem bērniem pirmsskolas izglītības iestādē
2021
Kvalifikācijas darba autore – Marta Meļehova. Kvalifikācijas darba tēma - “Muzikālās rotaļas skaņu diferencēšanai 2 – 3 gadus veciem bērniem pirmsskolas izglītības iestādē”. Kvalifikācijas darba vadītāja: Baiba Kaļķe. Pētījuma mērķis: Izpētīt apkārtnē dzirdamo skaņu diferencēšanas veicināšanas iespējas 2 – 3 gadus veciem bērniem pirmsskolas izglītības iestādē. Autore pēta literatūru par fonemātisko dzirdi un fonemātisko uztveri, tās nozīmi valodas attīstībā. Darbā tiek analizēti 2 – 3 gadus vecu bērnu veiksmīgas runas attīstības priekšnoteikumi. Darbā izzināti skaņu izrunas traucējumu iemesli 2 – 3 gadus veciem bērniem un pētītas apkārtnē dzirdamo skaņu diferencēšanas veicināšanas iespējas …
HUMAN CERVICO-FACIAL ACTINOMYCOSIS: Actinomyces in chronic granulomatous disease, epidemiological and clinical comments
2022
In a retrospective investigation performed in the department of Surgical Odontostomatology of Palermo University Polyclinic from 2012 to 2021, the Author examined 10 cases of cervico-facial actinomycosis, taking into consideration age range, gender distribution, predisposing factors and symptoms. In concordance with reports in literature,she found that the disease was perimandibular in 65%; she also report the diagnostic methods and therapeutic approaches used in the study
Skin Immunomodulation during Regeneration: Emerging New Targets
2021
Adipose-Derived Stem Cells (ADSC) are present within the hypodermis and are also expected to play a pivotal role in wound healing, immunomodulation, and rejuvenation activities. They orchestrate, through their exosome, the mechanisms associated to cell differentiation, proliferation, and cell migration by upregulating genes implicated in different functions including skin barrier, immunomodulation, cell proliferation, and epidermal regeneration. ADSCs directly interact with their microenvironment and specifically the immune cells, including macrophages and T and B cells, resulting in differential inflammatory and anti-inflammatory mechanisms impacting, in return, ADSCs microenvironment and …
Hopes and Limits of Adipose-Derived Stem Cells (ADSCs) and Mesenchymal Stem Cells (MSCs) in Wound Healing
2020
Adipose tissue derived stem cells (ADSCs) are mesenchymal stem cells identified within subcutaneous tissue at the base of the hair follicle (dermal papilla cells), in the dermal sheets (dermal sheet cells), in interfollicular dermis, and in the hypodermis tissue. These cells are expected to play a major role in regulating skin regeneration and aging-associated morphologic disgraces and structural deficits. ADSCs are known to proliferate and differentiate into skin cells to repair damaged or dead cells, but also act by an autocrine and paracrine pathway to activate cell regeneration and the healing process. During wound healing, ADSCs have a great ability in migration to be recruited rapidly…
Maturation of Epidermal Langerhans Cells In Vitro Is Accompanied by Downregulation of 4F2 (CD98) as Determined by Differential Display
1998
Following short-term culture, Langerhans cells mature morphologically and functionally into potent immunostimulatory cells. As regulation of gene expression accompanies this maturation process, it is likely that differentially expressed genes are involved in the maturation events. Using the recently described method of differential display, we generated cDNA expression patterns starting with mRNA of murine epidermal Langerhans cells isolated either directly (fLC) or following 3 d cultivation (cLC). Five hundred putative differentially expressed cDNA fragments were recovered from the gel. For a part of the fragments differential expression was confirmed by dot blot and Southern hybridization…
Excessive Daytime Sleepiness in Obstructive Sleep Apnea Patients Treated With Continuous Positive Airway Pressure: Data From the European Sleep Apnea…
2021
Excessive daytime sleepiness (EDS) is a symptom of obstructive sleep apnea (OSA) that resolves under treatment with continuous positive airway pressure (CPAP). In some patients, sleepiness persists despite CPAP treatment. We retrospectively analyzed data on subjective residual EDS, assessed as an Epworth Sleepiness Scale score (ESS) >10, in patients from the European Sleep Apnea Database (n = 4,853, mean age +/- SD 54.8 +/- 11.8 years, 26.1% females), at baseline and at the first visit (median follow-up: 5 months, interquartile range 3-13). An ESS > 10 occurred in 56% of patients at baseline and in 28.2% of patients at follow-up. Residual EDS was analyzed in 2,190 patients (age: 55.1 +/- 12…
Skolēna smadzeņu puslodes dominantes un prasmju attīstības ietekme uz mācību procesu matemātikas priekšmetā, tēmās par telpiskiem ķermeņiem, balstoti…
2020
Darba mērķis ir izpētīt smadzeņu puslodes dominantes ietekmi uz skolēna domāšanas un atrisinājuma meklēšanas gaitu uzdevumos par telpiskajiem ķermeņiem un izveidot palīgmateriālus skolēniem ar vājāk attīstītu telpisko domāšanu . Pētījuma gaitā tiek plānots apkopot informāciju par mācību procesa diferencēšanu un smadzeņu puslodes dominantes ietekmi uz mācīšanos , un veikt nelielas grupas izpēti pēc Gardnera testa un novērot tās rīcību, risinot uzdevumus, kas saistās ar telpisko iztēli. Izveidot un aprobēt uz nelielas grupas palīgmateriālus skolēniem ar vājāk attīstītu telpisko domāšanu. Tiek prognozēts, ka skolēniem, ar dominējošo kreiso smadzeņu puslodi, risinot uzdevumus par telpiskiem ķer…