Search results for "DISCIPLINE"
showing 10 items of 2858 documents
Response repetition vs. response change modulates behavioral and electrophysiological effects of distraction
2004
If stimulation occasionally contains distracting information, behavioral responses to task-relevant aspects of the stimulation are prolonged and more error prone. Additionally, event-related potentials (ERPs) acquired in an auditory distraction paradigm show that the distracting information elicits the components mismatch negativity (MMN), P3a and reorienting negativity (RON). Here, we assess to what extent sequential dependencies in the stimulation influence such indicators of distraction. Data of four experiments were reanalyzed for response repetition and response change trials separately. Behavioral performance on Deviants suggests markedly smaller distraction effects in change compared…
Trait anxiety and autonomic indicators of the processing of threatening information: a cued S1-S2 paradigm.
2004
Abstract The aim of this study was to use autonomic parameters in a cued S1–S2 task to examine associations between the processing of threatening information and trait anxiety in normal individuals. Forty-six student volunteers were designated high- or low-anxious due to pre-defined cutoff scores on the STAI. A cued S1–S2 task was presented in which the type of warning signal (S1) was consistently related to either threatening or non-threatening pictures (S2). Ten threat and 10 non-threat pictures were randomly presented. Heart rate and electrodermal activity were recorded in the time interval between S1 and S2. Results indicated deeper heart rate decelerations on threatening trials in high…
Implicit and explicit self-concept of neuroticism in borderline personality disorder
2019
In the past, research on personality in borderline personality disorder (BPD) used primarily questionnaires suggesting heightened neuroticism in BPD. Self-report instruments inform about the conscious or explicit self-concept. BPD patients are known to show negative distortion with exaggeration of negative affect in the self-report. Neuroticism represents a risk factor for mental disorders. Indirect measures are available that tap into the implicit self-concept of neuroticism. The implicit self-concept refers to individual differences in associative representations of the self. The present study examined for the first time the implicit in addition to the explicit self-concept of neuroticism…
Distinguishing Comorbidity and Successful Management of Adult ADHD
2012
Objective: Given high rates of comorbidity, lack of awareness and global acceptance, and varying guidelines for its management, adult ADHD may be an especially difficult condition to diagnose and treat. The objective of this review was to explore and characterize similarities and differences among comorbidities associated with adult ADHD. Method: A review of the literature over the past 10 years was performed using Ovid. Results: A myriad of comorbid conditions such as impulse-control/personality, anxiety, mood, substance use, learning, and sleep disorders overlap with adult ADHD. Furthermore, a number of such conditions have symptoms that can mimic those of ADHD, including hyperactivity, …
Rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression.
1996
Summary Background Lesion and neuroimaging studies suggest that left prefrontal lobe dysfunction is pathophysiologically linked to depression. Rapid-rate transcranial magnetic stimulation (rTMS) to prefrontal structures has a lateralised effect on mood in normal volunteers, and several preliminary studies suggest a beneficial effect of rTMS on depression. However, adequately controlled studies have not been conducted. Methods We have studied the effects of focal rTMS on the depressive symptoms in 17 patients with medication-resistant depression of psychotic subtype. The study was designed as a multiple cross-over, randomised placebo-controlled trial. Sham rTMS and stimulation of different c…
"…The times they aren't a-changin'…" rTMS does not affect basic mechanisms of temporal discrimination: a pilot study with ERPs.
2014
In time processing, the role of different cortical areas is still under investigation. Event-related potentials (ERPs) represent valuable indices of neural timing mechanisms in the millisecond-to-second domain. We used an interference approach by repetitive TMS (rTMS) on ERPs and behavioral performance to investigate the role of different cortical areas in processing basic temporal information. Ten healthy volunteers were requested to decide whether time intervals between two tones (S1-S2, probe interval) were shorter (800 ms), equal to, or longer (1200 ms) than a previously listened 1000-ms interval (target interval) and press different buttons accordingly. This task was performed at the b…
Modulating memory performance in healthy subjects with Trancranial Direct Current Stimulation over the right dorsolateral prefrontal cortex
2015
Objective: The role of the Dorsolateral Prefrontal Cortex (DLPFC) in recognition memory has been well documented in lesion, neuroimaging and repetitive Transcranial Magnetic Stimulation (rTMS) studies. The aim of the present study was to investigate the effects of transcranial Direct Current Stimulation (tDCS) over the left and the right DLPFC during the delay interval of a non-verbal recognition memory task. Method: 36 right-handed young healthy subjects participated in the study. The experimental task was an Italian version of Recognition Memory Test for unknown faces. Study included two experiments: in a first experiment, each subject underwent one session of sham tDCS and one session of…
Sex differences in interhemispheric communication during face identity encoding: Evidence from ERPs
2013
Sex-related hemispheric lateralization and interhemispheric transmission times (IHTTs) were examined in twenty-four participants at the level of the first visual ERP components (P1 and N170) during face identity encoding in a divided visual-field paradigm. While no lateralization-related and sex-related differences were reflected in the P1 characteristics, these two factors modulated the N170. Indeed, N170 amplitudes indicated a right hemisphere (RH) dominance in men (and a more bilateral functioning in women). N170 latencies and the derived IHTTs confirmed the RH advantage in men but showed the reverse asymmetry in women. Altogether, the results of this study suggest a clear asymmetry in m…
Prefrontal and temporo-parietal involvement in taking others' perspective: TMS evidence.
2008
INTRODUCTION: Understanding the mental states of others entails a number of cognitive processes known as Theory of Mind (ToM). Behavioural and functional neuroimaging evidence suggests that prefrontal and temporo-parietal cortices are involved in these abilities. The present study was aimed at investigating the role of the dorsolateral prefrontal cortex and temporo-parietal junction in ToM by using a repetitive transcranial magnetic stimulation (rTMS) paradigm. MATERIAL AND METHODS: Eleven healthy subjects participated in the study. The experimental ToM procedure was constituted by false belief and faux-pas written stories. Subjects were evaluated in baseline condition (Sham) and after 1Hz …
Lateralized effects of self-induced sadness and happiness on corticospinal excitability.
1997
We studied the changes in excitability of the corticospinal projection evoked by self-induced sad and happy thoughts. Corticospinal excitability was probed using focal, single-pulse transcranial magnetic stimulation (TMS) applied to the optimal scalp position for evoking motor potentials in the contralateral first dorsal interosseus muscle. Fourteen right-handed subjects were studied while counting mentally, thinking sad thoughts, or thinking happy thoughts. In each of these three conditions TMS was applied in each subject randomly, 20 times to the right and 20 times to the left hemisphere. Sad thoughts resulted in a significant facilitation of the motor potentials evoked by left-hemispheri…