Search results for "DISEASE"

showing 10 items of 52575 documents

Evolution of the Dentition in Holocephalans (Chondrichthyes) Through Tissue Disparity

2020

Abstract The Holocephali is a major group of chondrichthyan fishes, the sister taxon to the sharks and rays (Elasmobranchii). However, the dentition of extant holocephalans is very different from that of the elasmobranchs, lacking individual tooth renewal, but comprising dental plates made entirely of self-renewing dentine. This renewal of all tissues occurs at the postero-lingual plate surface, as a function of their statodont condition. The fossil record of the holocephalans illuminates multiple different trends in the dentition, including shark-like teeth through to those with dentitions completely lacking individual teeth. Different taxa illustrate developmental retention of teeth but w…

0106 biological sciences0301 basic medicinePlant Science010603 evolutionary biology01 natural sciences03 medical and health sciencesCalcification Physiologicstomatognathic systemExtant taxonElasmobranchiiAnimalsDentitionFossil RecordbiologyDentitionFishesBiological evolutionAnatomybiology.organism_classificationBiological EvolutionChondrichthyesHolocephalistomatognathic diseases030104 developmental biologyAnimal Science and ZoologyWear resistantToothIntegrative and Comparative Biology
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Proposal of a Citrus translational genomic approach for early and infield detection of Flavescence dorée in Vitis

2014

Flavescence dore´e (FD) is one of the most widely known grapevine yellows disease and one of the most unabated worldwide in the viticulture sector. In this paper, we outline a strategy for developing an integrated system of technologies to enable rapid, early disease FD detection and diagnosis. We propose the deployment of a newly developed sensor device, the differential mobility spectrometer (DMS), which has shown positive results with a similar vector-borne disease in Citrus. We have previously demonstrated that the gas chromatograph DMS (GC/DMS) can distinguish various citrus diseases, and the system may also allow detection of volatile organic compound (VOC) signals from a tree of othe…

0106 biological sciences0301 basic medicinePlant ScienceComputational biologyBiology01 natural sciences03 medical and health sciencesSettore AGR/07 - Genetica AgrariaBotanyProfile analysisPlant systemEcology Evolution Behavior and SystematicsDifferential mobility spectrometer early detection Flavescence dore´e phytoplasma qRT-PCR ELISA VitisfungiEarly diseasefood and beveragesSettore AGR/12 - Patologia VegetaleGrapevine yellowsSettore AGR/02 - Agronomia E Coltivazioni ErbaceeSettore AGR/03 - Arboricoltura Generale E Coltivazioni Arboree030104 developmental biologySettore AGR/14 - PedologiaFlavescence doréeGas chromatographyGas chromatography–mass spectrometryDisease transmission010606 plant biology & botany
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Holm Oak Somatic Embryogenesis: Current Status and Future Perspectives

2019

Quercus ilex (holm oak) is one of the most representative trees in the Mediterranean basin, but now the sustainability of its ecosystems is at serious risk due to the lack of natural regeneration and to the presence of a severe disease called oak decline that has caused the death of thousands of trees. The application of biotechnological tools, such as somatic embryogenesis, allows programs of genetic improvement of the species to be speeded up and helps in the conservation of its ecosystems. Somatic embryogenesis is currently considered one of the main biotechnological techniques that has demonstrated significant benefits when has applied to forest tree species, providing significant advan…

0106 biological sciences0301 basic medicinePlant growthSomatic embryogenesisSevere diseaseReviewNatural regenerationPlant Sciencelcsh:Plant cultureBiologycryopreservation01 natural sciencesMediterranean BasinAcclimatization03 medical and health sciencesBotanylcsh:SB1-1110plant regenerationoak declineOak declinesomatic embryosQuercus ilex030104 developmental biologygenetic transformation010606 plant biology & botanyExplant cultureFrontiers in Plant Science
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Potential impact of genetically modified Lepidoptera-resistant Brassica napus in biodiversity hotspots: Sicily as a theoretical model

2018

The general increase of the cultivation and trade of Bt transgenic plants resistant to Lepidoptera pests raises concerns regarding the conservation of animal and plant biodiversity. Demand for biofuels has increased the cultivation and importation of oilseed rape (Brassica napus L.), including transgenic lines. In environmental risk assessments (ERAs) for its potential future cultivation as well as for food and feed uses, the impact on wild Brassicaeae relatives and on non-target Lepidoptera should be assessed. Here we consider the potential exposure of butterflies as results of possible cultivation or naturalization of spilled seed in Sicily (Italy). Diurnal Lepidoptera, which are pollinat…

0106 biological sciences0301 basic medicinePollinationPopulationBiodiversitymedicine.disease_cause010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyLepidoptera genitalia03 medical and health sciencesPollinatorPollenmedicineNectareducationEcology Evolution Behavior and Systematicseducation.field_of_studybiologyfungifood and beveragesbiology.organism_classification030104 developmental biologyAgronomyInsect ScienceAgronomy and Crop SciencePieridaeInsect Science
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Cannibalism facilitates gigantism in a nine-spined stickleback (Pungitius pungitius) population

2016

Cannibalism is a taxonomically widespread phenomenon that can fundamentally affect the structure and stability of aquatic communities, including the emergence of a bimodal size distribution (“dwarfs” and “giants”) in fish populations. Emergence of giants could also be driven or facilitated by parasites that divert host resources from reproduction to growth. We studied the trophic ecology of giant nine-spined sticklebacks (Pungitius pungitius) in a Finnish pond to evaluate the hypotheses that gigantism in this population would be facilitated by cannibalism and/or parasitic infections by Schistocephalus pungitii cestode. Stomach content analyses revealed an initial ontogenetic dietary shift f…

0106 biological sciences0301 basic medicinePopulationparasitismSchistocephalus pungitiiAquatic ScienceBiology010603 evolutionary biology01 natural sciencesPredation03 medical and health sciencesPungitiusmedicinestable isotope analysisindividual specialisation14. Life underwatereducationEcology Evolution Behavior and SystematicsTrophic levelIsotope analysisstomach content analysiseducation.field_of_studyEcologyEcologyCannibalismSticklebackmedicine.diseasebiology.organism_classificationGigantism030104 developmental biologyta1181Ecology of Freshwater Fish
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Molecular signatures of silencing suppression degeneracy from a complex RNA virus

2021

As genomic architectures become more complex, they begin to accumulate degenerate and redundant elements. However, analyses of the molecular mechanisms underlying these genetic architecture features remain scarce, especially in compact but sufficiently complex genomes. In the present study, we followed a proteomic approach together with a computational network analysis to reveal molecular signatures of protein function degeneracy from a plant virus (as virus-host protein-protein interactions). We employed affinity purification coupled to mass spectrometry to detect several host factors interacting with two proteins of Citrus tristeza virus (p20 and p25) that are known to function as RNA sil…

0106 biological sciences0301 basic medicineProteomicsCitrusInteraction NetworksPathogenesisPlant Sciencemedicine.disease_causePathology and Laboratory Medicine01 natural sciencesInteractomeBiochemistryBimolecular fluorescence complementationRNA interferenceRNA silencing supressorsCitrus tristeza virusMedicine and Health SciencesDegeneracy (biology)Protein Interaction MapsBiology (General)H20 Plant diseasesPlant ProteinsEcologybiologyPlant virusesEukaryotaArgonautePlantsSmall interfering RNANucleic acidsRNA silencingComputational Theory and MathematicsGenetic interferenceExperimental Organism SystemsModeling and SimulationProteomeArgonaute ProteinsHost-Pathogen InteractionsRNA ViralEpigeneticsResearch ArticleClosterovirusRNA virusViral proteinQH301-705.5Arabidopsis ThalianaPlant PathogensComputational biologyGenome ViralBrassicaResearch and Analysis MethodsModels BiologicalPlant Viral Pathogens03 medical and health sciencesCellular and Molecular NeuroscienceViral ProteinsModel OrganismsPlant and Algal ModelsTobaccomedicineGeneticsGenomesNon-coding RNAProtein InteractionsMolecular signaturesMolecular BiologyEcology Evolution Behavior and SystematicsPlant DiseasesHost Microbial InteractionsBiology and life sciencesMass spectrometryOrganismsComputational BiologyProteinsRNA virusPlant Pathologybiology.organism_classificationGene regulationRepressor Proteins030104 developmental biologyU30 Research methodsAnimal StudiesRNAGene expression010606 plant biology & botanyF30 Plant genetics and breeding
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Invasive parasites are detectable by their abundance-occupancy relationships: the case of helminths from Liza haematocheilus (Teleostei: Mugilidae)

2018

Abstract The biogeographic patterns of abundance and prevalence of helminths from Liza haematocheilus were studied across its native (Sea of Japan) and introduced (Sea of Azov) distribution ranges. Abundance-occupancy relationships (AORs) were tested for the core-satellite and enemy release (ERH) species hypotheses in eight and 14 host samples from the native and introduced host ranges, respectively. The AOR model fitted parasite data extremely well, irrespective of whether the host or the parasite species were native or invasive. Except for co-introduced monogeneans, species were less abundant and prevalent in the introduced host population than in the native one, which agrees well with th…

0106 biological sciences0301 basic medicineRange (biology)PopulationZoologyBiologyGeneralist and specialist species010603 evolutionary biology01 natural sciencesFish Diseases03 medical and health sciencesAbundance (ecology)HelminthsAnimalsParasite hostingHelminths[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology14. Life underwatereducationComputingMilieux_MISCELLANEOUSParasitic life cycleseducation.field_of_studyPacific OceanHost (biology)Fishes030104 developmental biologyInfectious DiseasesParasitologyHelminthiasis AnimalIntroduced Species[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/SymbiosisInternational Journal for Parasitology
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Exposure to environmental radionuclides is associated with altered metabolic and immunity pathways in a wild rodent

2019

Wildlife inhabiting environments contaminated by radionuclides face putative detrimental effects of exposure to ionizing radiation, with biomarkers such as an increase in DNA damage and/or oxidative stress commonly associated with radiation exposure. To examine the effects of exposure to radiation on gene expression in wildlife, we conducted a de novo RNA sequencing study of liver and spleen tissues from a rodent, the bank vole Myodes glareolus. Bank voles were collected from the Chernobyl Exclusion Zone (CEZ), where animals were exposed to elevated levels of radionuclides, and from uncontaminated areas near Kyiv, Ukraine. Counter to expectations, we did not observe a strong DNA damage resp…

0106 biological sciences0301 basic medicineRodentDNA Repairmedicine.disease_cause01 natural sciencessäteilybiologiachemistry.chemical_compoundRadiation IonizingMyodes glareolusstable isotopepollutionaineenvaihduntaBeta oxidationradionuclides2. Zero hungerbiologyArvicolinaeFatty AcidsRadiation ExposureRNAseqBank voleMolecular AdaptationLiverimmuunijärjestelmäOriginal ArticleUkraineOxidation-ReductionmetsämyyräDNA damageDNA repair010603 evolutionary biologyMicrobiology03 medical and health sciencesImmunitybiology.animalGeneticsmedicineAnimalsEcology Evolution Behavior and SystematicsRadioisotopesFatty acid metabolismLipid metabolismDNAbiology.organism_classificationLipid MetabolismOxidative Stress030104 developmental biologychemistryChernobyl Nuclear Accident13. Climate actionImmune SystemRNAORIGINAL ARTICLESOxidative stressSpleenDNA DamageMutagens
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Borrelia afzeliialters reproductive success in a rodent host

2018

The impact of a pathogen on the fitness and behaviour of its natural host depends upon the host–parasite relationship in a given set of environmental conditions. Here, we experimentally investigated the effects ofBorrelia afzelii,one of the aetiological agents of Lyme disease in humans, on the fitness of its natural rodent host, the bank vole (Myodes glareolus), in semi-natural conditions with two contrasting host population densities. Our results show thatB. afzeliican modify the reproductive success and spacing behaviour of its rodent host, whereas host survival was not affected. Infection impaired the breeding probability of large bank voles. Reproduction was hastened in infected females…

0106 biological sciences0301 basic medicineRodentmetsämyyräOffspringHost–pathogen interactionZoologyzoonoosithost-pathogen interactionBorrelia afzeliimedicine.disease_cause010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesbiology.animalMyodes glareolusisäntäeläimetnatural hostmedicineMatingGeneral Environmental ScienceEcologyGeneral Immunology and MicrobiologybiologyReproductive successHost (biology)General Medicinezoonosislisääntyminenbiology.organism_classificationfitnessBorrelia-bakteeritBank vole030104 developmental biologyBorrelia afzeliita1181host–pathogen interactionGeneral Agricultural and Biological SciencesProceedings of the Royal Society B: Biological Sciences
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Oxidative stress and senescence in social insects: A significant but inconsistent link?

2021

The life-prolonging effects of antioxidants have long entered popular culture, but the scientific community still debates whether free radicals and the resulting oxidative stress negatively affect longevity. Social insects are intriguing models for analysing the relationship between oxidative stress and senescence because life histories differ vastly between long-lived reproductives and the genetically similar but short-lived workers. Here, we present the results of an experiment on the accumulation of oxidative damage to proteins, and a comparative analysis of the expression of 20 selected genes commonly involved in managing oxidative damage, across four species of social insects: a termit…

0106 biological sciences0301 basic medicineSenescenceAgingmedia_common.quotation_subjectLongevityZoologyIsopteraBiologySocial insectsAffect (psychology)Protein oxidationmedicine.disease_cause010603 evolutionary biology01 natural sciencesAntioxidantsGeneral Biochemistry Genetics and Molecular BiologyTranscriptomes03 medical and health sciencesSpecies SpecificitymedicineAnimalsResearch ArticlesSocialitymedia_commonAntsLongevityArticlesBeesANTOxidative StressAgeing030104 developmental biologyAgeingAntioxidant genesGeneral Agricultural and Biological SciencesProtein oxidationOxidative stress
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