Search results for "DMA"
showing 10 items of 315 documents
Long-term effects of repeated social stress on the conditioned place preference induced by MDMA in mice.
2015
Previous studies have demonstrated that social defeat stress increases the rewarding effects of psychostimulant drugs such as cocaine and amphetamine. In the present study we evaluated the long-term effects of repeated social defeat (RSD) on the rewarding effects of ±3,4-methylenedioxymethamphetamine (MDMA) hydrochloride in the conditioned place preference (CPP) paradigm. Adolescent and young adult mice were exposed to four episodes of social defeat (on PND 29-40 and PND 47-56, respectively) and were conditioned three weeks later with 1.25 or 10mg/kg i.p. of MDMA (experiment 1). The long-term effects of RSD on anxiety, social behavior and cognitive processes were also evaluated in adult mic…
Decreased plasma soluble RAGE in patients with hypercholesterolemia: Effects of statins
2007
The receptor for advanced glycation endproducts (RAGE) is overexpressed at sites of vascular pathology. A soluble RAGE isoform (sRAGE) neutralizes the ligand-mediated damage by acting as a decoy. We hypothesized that in hypercholesterolemia up-regulation of the ligand-RAGE axis may bridge impairment of nitric oxide biosynthesis with oxidative stress. We measured in 60 hypercholesterolemic patients and 20 controls plasma total sRAGE levels, urinary 8-iso-prostaglandin (PG) F(2alpha) excretion, and plasma levels of asymmetric dimethylarginine (ADMA). The effects of two structurally different statins (pravastatin and atorvastatin) on these parameters were analyzed in 20 hypercholesterolemic su…
A Proposal for Novel Standards of Histopathology Reporting for D3 Lymphadenectomy in Right Colon Cancer: The Mesocolic Sail and Superior Right Colic …
2020
Background Strong agreement exists concerning the standards of pathologic reporting for total mesorectal excision and complete mesocolic excision. It represents a quality standard that correlates with survival. However, no agreed standards of reporting are available to define D3 lymphadenectomy for right colectomy. Objective The purpose of this study was to define anatomopathological standards of specimen quality obtained from the surgical specimen when an oncologic right hemicolectomy with D3 lymphadenectomy has been correctly performed. Design This study was conducted in 2 different phases. The first part consisted of a cadaver-based study of right colon anatomy, and the second part consi…
Keeping memory for intentions: A cTBS investigation of the frontopolar cortex
2011
The present study aimed to investigate the role of frontopolar cortex in prospective memory (PM) by means of inhibitory theta-burst stimulation (cTBS). "Experiment 1"-8 volunteers were evaluated after inhibitory cTBS over left Brodmann area (BA) 10, right BA10, and Cz. In the PM procedure, sequences of 4 words each were presented. During the intersequence delay, subjects had to repeat the sequence in the observed order (ongoing task forward) or in the reverse order (backward). At the occurrence of a target word, subjects had to press a key on the keyboard (PM task). Recall and recognition of the target words were also tested. PM accuracy was lower after cTBS over left BA10 compared with Cz …
The Right Frontopolar Cortex Is Involved in Visual-Spatial Prospective Memory
2013
The involvement of frontopolar cortex in mediating prospective memory processes has been evidenced by various studies, mainly by means of neuroimaging techniques. Recently, one transcranial magnetic stimulation study documented that transient inhibition of left Brodmann Area (BA) 10 impaired verbal prospective memory. This result raises the issue of whether the BA 10 involvement in prospective memory functioning may be modulated by the physical characteristics of the stimuli used. The present study aimed to investigate the role of the frontopolar cortex in visual-spatial PM by means of the application of inhibitory theta-burst stimulation. Twelve volunteers were evaluated after inhibitory t…
Osteogenic potential of a biosilica-coated P(UDMA-co-MPS) copolymer
2020
A P(UDMA-co-MPS) copolymer was surface-functionalized through the polycondensation activity of the enzyme silicatein. The resulting biosilica coating significantly enhanced mineralization of osteoblastic cells, thereby revealing its osteogenic potential. Consequently, the functionalized copolymer may be explored as an alternative to conventionally used acrylics in applications where stable bone-material interfaces are required.
Coffee grounds as filler for pectin: Green composites with competitive performances dependent on the UV irradiation.
2017
Novel composite bioplastics were successfully prepared by filling pectin matrix with treated coffee grounds. The amount of coffee dispersed into the pectin was changed within a wide filler range. The morphology of the pectin/coffee hybrid films was studied by microscopic techniques in order to investigate their mesoscopic structure as well as the sizes distribution of the particles dispersed into the matrix. The micrographs showed that the coffee grounds are uniformly dispersed within the polymeric matrix. The morphological characteristics of the biocomposite films were correlated to their properties, such as wettability, water uptake, thermal behavior and mechanical performances. Dynamic m…
Energy-efficient resource allocation for OFDMA two-way relay networks with imperfect CSI
2015
Most of the existed works on the radio resource allocation (RRA) problem commonly assume the channel-state information (CSI) can be perfectly obtained by the transmission source. However, such assumption is not practical in the realistic wireless systems. In this work, we consider the practical implementation issues of resource allocation in orthogonal frequency division multiple access (OFDMA) two-way relay networks: the inaccuracy of channel-state information (CSI) available to the source. Instead, only the estimated channel status is known by the source. In this context, a joint optimization of subcarrier pairing and allocation, relay selection, and transmit power allocation is formulate…
Diatom species composition and indices for determining the ecological status of coastal Mediterranean Spanish lakes
2013
Diatom indices have been used and tested mainly for assessing the ecological status of rivers and deep lakes, but there are scarce studies that determine their effectiveness in shallow lakes and in coastal Mediterranean lakes. This study evaluates the validity of several common diatom indices (SPI, BDI, CEC and TDIL) for the determination of the ecological quality of three coastal lakes (Valencia, Spain) and presents descriptions and ecological data of the main diatom species recorded. Diatom samples were collected from phytobenthos, both from epiphyton of the dominant submerged macrophytes and the sediment. The ecological status of the systems was determined according to different physico-…
Novel GaN Based Solid State Power Amplifiers, Results, Advances and Comparison with Vacuum Tubes Based Microwave Power Modules
2018
Power amplifiers based on vacuum tubes or solid state are key items in a number of systems. Solid state technology is growing up for some applications and it may be complementary to the vacuum technology. This paperwork presents SSPA operational principles and performance. The GaN technology available in the market, the technology roadmap, a comparison with the vacuum tubes are introduced