Search results for "DOC"
showing 10 items of 14105 documents
The reactivity of neonatal rabbits to the mammary pheromone as a probe for viability
2012
International audience; Newborn rabbits depend on a daily nursing interaction with the mother to gain milk and to survive. During this interaction, they localise and seize the nipples displaying a typical behaviour triggered by maternal odour cues. The mammary pheromone constitutes such a signal in domestic rabbits: it elicits sucking-related movements in more than 90% of the pups. However, some newborns remain unresponsive to the presentation of the pheromone, even pups apparently healthy and highly motivated to suck. The main goal of the present study was therefore to explore the link between the unresponsiveness of rabbit pups to the mammary pheromone and their growth and survival in bre…
Physical inactivity increases oxidative stress, endothelial dysfunction, and atherosclerosis.
2005
Objective— Sedentary lifestyle is associated with increased cardiovascular events. The underlying molecular mechanisms are incompletely understood. Reactive oxygen species (ROS) contribute to endothelial dysfunction and atherosclerosis. An important source of vascular ROS is the NADPH oxidase. Methods and Results— C57BL6 mice were subjected to regular housing (physical inactivity) or voluntary training on running wheels (6 weeks). Inactivity increased vascular lipid peroxidation to 148±9% and upregulated superoxide release to 176±17% (L-012 chemiluminescence) and 188±29% (cytochrome C reduction assay), respectively. ROS production was predominantly increased in the endothelium and the medi…
An Endemic Plant of the Mediterranean Area: Phytochemical Characterization of Strawberry Tree (Arbutus unedo L.) Fruits Extracts at Different Ripenin…
2022
This work focused on the extraction, quantification, and characterization of bioactive compounds of Arbutus unedo L. fruits, comparing the results obtained from the different ripening states. Extractions were performed by different methods (such as maceration extraction and ultrasonic extraction) and food grade solvents (aqueous and hydroalcoholic solvents) in each of the all ripening states (four states considered, associated with four different colors, i.e., green, yellow, orange, and red). The presence of (poly)phenols was quantified and characterized, and scavenging activity was determined by the Folin–Ciocâlteu reagent and the DPPH method, respectively. The content of bioactive compoun…
Rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes): A multicenter retrospective nationwide Italian study a…
2017
Background Randomized controlled trials (RCTs) in the field of diabetes have limitations inherent to the fact that design, setting, and patient characteristics may be poorly transferrable to clinical practice. Thus, evidence from studies using routinely accumulated clinical data are increasingly valued. Aims We herein describe rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes), a multicenter retrospective nationwide study conducted at 50 specialist outpatient clinics in Italy and promoted by the Italian Diabetes Society. Data synthesis The primary objective of the study is to describe the baseline clinical characteristics (particularly HbA1c) of pa…
Enterobacter cloacae administration induces hepatic damage and subcutaneous fat accumulation in high-fat diet fed mice.
2018
Accumulating evidence indicates that gut microbiota plays a significant role in obesity, insulin resistance and associated liver disorders. Family Enterobacteriaceae and especially Enterobacter cloacae strain B29 have been previously linked to obesity and hepatic damage. The underlying mechanisms, however, remain unclear. Therefore, we comprehensively examined the effects of E. cloacae subsp. cloacae (ATCC® 13047™) administration on host metabolism of mice fed with high-fat diet (HFD). C57BL/6N mice were randomly divided into HFD control, chow control, and E. cloacae treatment groups. The E. cloacae treatment group received live bacterial cells in PBS intragastrically twice a week, every ot…
Fatty acid composition as biomarkers of freshwater microalgae: analysis of 37 strains of microalgae in 22 genera and in seven classes
2013
The fatty acid (FA) composition of algae is an important determinant of their food quality for consumers, and FAs can also be used as biomarkers for biochemical and energetic pathways in food webs. FA analyses of 7 freshwater algal classes and 37 strains showed clear similarity within classes and strong differences amongst classes. Class was a dominant factor (66.4%) explaining variation in FA signatures of microalgae. The 7 algal classes comprised 4 separate groups according to their FA profiles: (1) Chlorophyceae and Trebouxiophyceae, (2) Bacillariophyceae, (3) Cryptophyceae, Chrysophyceae, and Raphidophyceae, and (4) Euglenophyceae. Each group had a characteristic FA composition, althoug…
Eating behavior dimensions and 9-year weight loss maintenance : a sub-study of the Finnish Diabetes prevention study
2023
Abstract Background Behavioral processes through which lifestyle interventions influence risk factors for type 2 diabetes (T2DM), e.g., body weight, are not well-understood. We examined whether changes in psychological dimensions of eating behavior during the first year of lifestyle intervention would mediate the effects of intervention on body weight during a 9-year period. Methods Middle-aged participants (38 men, 60 women) with overweight and impaired glucose tolerance (IGT) were randomized to an intensive, individualized lifestyle intervention group (n = 51) or a control group (n = 47). At baseline and annually thereafter until nine years body weight was measured and the Three Factor Ea…
Realtà Aumentata e valorizzazione delle competenze didattiche in Università
2023
Il miglioramento della didattica universitaria e lo sviluppo professionale della docenza sono oggi al centro di un rinnovato e più maturo interesse da parte della comunità accademica e dei decisori politici. Essi non possono non considerare il ruolo apportato dalle tecnologie nei recenti e radicali cambiamenti delle esperienze di insegnamento e apprendimento. In questo panorama, la Realtà Aumentata (Augmented Reality, AR) è una tecnologia emergente. Numerose ricerche (Akçayır et al., 2017; Bacca et al., 2015; Chen et al., 2017; Dey et al., 2018; Fombona et al., 2017; Hantono et al., 2018; Li et al., 2016; Ozdemir et al., 2018; Radu, 2014; Sheehy et al., 2014; Tekedere et al., 2016) mettono…
Elaboració d'un Material per a alumnes de Magisteri: "Situacions d'aula"
2004
L' objectiu fonamental del present treball ha estat elaborar un volum on recollir la transcripció d'una situació d'aula d'Educació Primària enregistrada en vídeo i preparar-la com a material docent. El text transcrit ha estat dividit en episodis i seqüències que fan més abastable el material. Després de cada episodi s'ha formulat una sèrie de preguntes referents a les disciplines del currículum de mestre, per tal d'ajudar els estudiants a analitzar i interpretar la situació d'aula. El material pretén ser un instrument a l'abast dels estudiants i el professorat per tal de portar a terme tasques de treball cooperatiu i interdisciplinar. Les referències teòriques subjacents a aquest treball fo…
Reformas y práctica educativa en la formación inicial del profesorado en Bolivia: el caso de la Escuela Superior de Formación de Maestros "Enrique Fi…
2014
Reformas y práctica educativa en la Formación Inicial del Profesorado en Bolivia: El caso de la Escuela Superior de Formación de Maestros “Enrique Finot” del Departamento de Santa Cruz. Esta investigación aborda la problemática docente, más concretamente en el área de la Formación Inicial– en el proceso de reforma educativa (Ley 1565) que se trató de implementar en Bolivia desde el año 1994, en el marco de las reformas educativas implementadas en América Latina. El objetivo está orientado al análisis reflexivo de la práctica docente, en el contexto que establece la práctica educativa, utilizando como caso concreto la Escuela Superior de Formación de Maestros “Enrique Finot”, del Departament…