Search results for "DOC"
showing 10 items of 14105 documents
Human Papillomavirus Types 16, 18, and 31 Share Similar Endocytic Requirements for Entry
2013
ABSTRACT Human papillomavirus type 18 (HPV18), one of the HPVs with malignant potential, enters cells by an unknown endocytic mechanism. The key cellular requirements for HPV18 endocytosis were tested in comparison to those for HPV16 and -31 endocytoses. HPV18 (like HPV16 and -31) entry was independent of clathrin, caveolin, dynamin, and lipid rafts but required actin polymerization and tetraspanin CD151, and the viruses were routed to the same LAMP-1-positive compartment. Hence, the viruses shared similar cellular requirements for endocytic entry.
Clathrin- and Caveolin-Independent Entry of Human Papillomavirus Type 16—Involvement of Tetraspanin-Enriched Microdomains (TEMs)
2008
BACKGROUND: Infectious entry of human papillomaviruses into their host cells is an important step in the viral life cycle. For cell binding these viruses use proteoglycans as initial attachment sites. Subsequent transfer to a secondary receptor molecule seems to be involved in virus uptake. Depending on the papillomavirus subtype, it has been reported that entry occurs by clathrin- or caveolin-mediated mechanisms. Regarding human papillomavirus type 16 (HPV16), the primary etiologic agent for development of cervical cancer, clathrin-mediated endocytosis was described as infectious entry pathway. METHODOLOGY/PRINCIPAL FINDINGS: Using immunofluorescence and infection studies we show in contra…
Procedures for study of teaching practices. Literature Review
2012
Interest in studying teaching practices has increased, because of the need to evaluate teachers and dissatisfaction with the usual ways of doing it. Recent approaches with Value-Added Models, based on students’ results on achievement tests do not seem satisfactory. The article is based on a review of literature and classifies the approaches to practices in three groups: instruments based on information given by teachers; observation protocols; and approaches based on the analysis of products of the practices. Specific tools are described and advantages and disadvantages of the three approaches are discussed. El interés por las prácticas docentes ha aumentado, en parte por la necesidad de ev…
Hothousing: Utilising industry collaborative problem-solving practices for STEAM in schools
2022
Collaborative problem solving (CPS) has been widely used in both industry and in schools over at least the last twenty years. The Industry Hothousing variant of CPS in its adult format is an intensive, time-constrained workshop based process designed to build mutual trust between customers and industry experts in order to synergically develop creative solutions together. Its potential use in schools raises two important questions: Firstly, what degree of structure and support is required to unleash student creativity and enhance learning - as in industry or does the student need more structured methods including explicitly being taught collaborative problem solving skills? Secondly, is CPS …
Due città, un porto, un unico waterfront
2011
Nel mosaico di culture del Mediterraneo (Matvejvich P., 2006), la regione costiera del fronte africano della Sicilia può recuperare una nuova centralità attraverso la riscoperta del milieu storico culturale e l’attivazione di quel milieu creativo (Carta M., 2008) capace di alimentare idee e progetti condivisi. Ripensare ad un unico waterfront della Valle dei Templi, patrimonio dell’Umanità, che parta da Porto Empedocle e giunga fino a San Leone (la borgata marinara di Agrigento), potrebbe rappresentare una preziosa occasione per rigenerare le aree di waterfront, affidando al porto di Porto Empedocle, e alla realtà urbana, un ruolo innovativo in simbiosi con la sua città-madre, Agrigento, re…
Asking for medical help by posting on the net: genre, functions and ethical issues
2014
On the basis of the growing of the number of sites related to health issues and online conversation, statistical research tend to acknowledge that the communication practices of health message boards have significant roles to play in the era of online counseling (Anderson, 2003; Kim & Yoon, 2011; Mulholland, 1999; Eysenbach and Diepgen 1999; O'Connor and Johanson 2000; Shuyler and Knight 2003; Gooden and Winefield 2007). However, one of the main worries concerning these spaces has been the uncontrolled information that is provided by users with no defined roles and who do not/cannot take responsibility for what they say. Previous studies were intended to explore how people discussing health…
W więzieniu widoczności medialnej. Rozważania o mikropolityce w "ponoptykonicznej rzeczywistości"
2017
W dobie telefonów komórkowych z dostępem do Internetu, wyposażonych w cyfrowe aparaty fotograficzne, „fotoreporterem” może zostać każdy. Dziś polityk nie tylko musi potrafić dobrze się zaprezentować, ale będąc ciągle narażonym na upublicznienie, kontrolować każdy swój gest i ważyć każde słowo. Każdy błąd czy gafa szybko może przerodzić się w poważny kryzys zagrażający wizerunkowi aktora politycznego. Na ciągłą widoczność narażone są nie tylko najważniejsze osoby w państwie, ale wręcz każdy. Co równie istotne, współczesna polityka oparta jest na ciągłej medialnej widoczności. Aktywna obecność na portalach społecznościowych staje się równie ważna, o ile nie ważniejsza od tego, kto i jak głoso…
Contre la fausse objectivité, le perspectivisme assumé ? le reportage « gonzo » de Goldin, Clark, D’Agata, Tillmans contre la photographie « document…
2019
International audience; Après 1945, un certain nombre de praticiens de la « photographie plasticienne »privilégièrent le reportage « communautaire » : une plongée, sur le long terme, au sein d’ungroupe d’individus, souvent connus, voire intimes, du photographe, qui loin de se placercomme un témoin neutre, activait le mécanisme de l’observation participante chère àl’ethnographie. Larry Clark en fournit un exemple avec la série Tulsa (1971), la premièred’une longue lignée. Nan Goldin amplifia d’autant l’inclusion de l’autrice par la pratique del’autoportrait en situation dans The Ballad of Sexual Dependency (1981-1996). Plus tard desartistes comme Antoine d’Agata ou Wolfgang Tillmans poursuiv…
Sustainable Supercapacitors Based on Polypyrrole-Doped Activated Biochar from Wood Waste Electrodes
2023
The synthesis of high-performance carbon-based materials from biomass residues for electrodes has been considered a challenge to achieve in supercapacitor-based production. In this work, activated biochar has been prepared as the active electrode material for supercapacitors (SCs), and an effective method has been explored to boost its capacitive performance by employing polypyrrole (PPy) as a biochar dopant. The results for physicochemical characterization data have demonstrated that PPy doping affects the biochar morphology, specific surface area, pore structure, and incorporation of surface functionalities on modified biochar. Biochar-PPy exhibited a surface area of 87 m2 g−1, while pris…
Doctoral studies in global time and change - female doctoral student and individual lifecourse in Finland
2013
Multiple global changes in the form of knowledge and the change in the doctoral education create the need to examine the current practices of doctoral degree. The change forces discussion about the future of doctoral education and the future of the prospective doctors. The doctoral education has to answer the demands set for it. Forming a comprehensive understanding requires an examination at the micro and macro level. In this article I examine the lifecourse of the under 40-year-old female doctoral student with a family and the significance of doctoral studies at the individual level. I concentrate on the personal lifecourse experiences of the women and on the chronological stories which a…