Search results for "DOM"

showing 10 items of 12668 documents

International BEAT-PCD Consensus Statement for Infection Prevention and Control for Primary Ciliary Dyskinesia in collaboration with ERN-LUNG PCD Cor…

2021

Introduction In primary ciliary dyskinesia (PCD) impaired mucociliary clearance leads to recurrent airway infections and progressive lung destruction, and concern over chronic airway infection and patient-to-patient transmission is considerable. So far, there has been no defined consensus on how to control infection across centres caring for patients with PCD. Within the BEAT-PCD network, COST Action and ERS CRC together with the ERN-Lung PCD core a first initiative has now been taken towards creating such a consensus statement. Methods A multidisciplinary international PCD expert panel was set up to create a consensus statement for infection prevention and control (IP&C) for PCD, covering …

:Otros calificadores::Otros calificadores::/prevención & control [Otros calificadores]Infeccions respiratòries en els infantsPrimary Ciliary DyskinesiaStatement (logic)Respiratory SystemMULTICENTERRECOMMENDATIONS0302 clinical medicineOriginal Research ArticlesPandemicSTENOTROPHOMONAS-MALTOPHILIAInfection control:Pathological Conditions Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic Disease [DISEASES]030212 general & internal medicinePrimary ciliary dyskinesiaMalalties transmissibles - Transmissió:Environmental Health::Health::Environmental Illness::Communicable Diseases::Communicable Disease Control [PUBLIC HEALTH]FOUNDATIONbiologyTransmission (medicine)R:Congenital Hereditary and Neonatal Diseases and Abnormalities::Congenital Abnormalities::Abnormalities Multiple::Ciliopathies::Congenital Hereditary and Neonatal Diseases and Abnormalities::Ciliary Motility Disorders [DISEASES]:afecciones patológicas signos y síntomas::procesos patológicos::atributos de la enfermedad::enfermedad crónica [ENFERMEDADES]:salud ambiental::salud::enfermedad ambiental::enfermedades transmisibles::control de enfermedades transmisibles [SALUD PÚBLICA]medicine.anatomical_structureMedicinePatient representativesLife Sciences & BiomedicinePulmonary and Respiratory Medicinemedicine.medical_specialty3610 Medicine & health:enfermedades y anomalías neonatales congénitas y hereditarias::anomalías congénitas::anomalías múltiples::ciliopatías::enfermedades y anomalías neonatales congénitas y hereditarias::trastornos de la motilidad ciliar [ENFERMEDADES]:Other subheadings::Other subheadings::/prevention & control [Other subheadings]03 medical and health sciencesotorhinolaryngologic diseasesmedicineIntensive care medicineScience & TechnologyCYSTIC-FIBROSISLungbusiness.industryPSEUDOMONAS-AERUGINOSAMalalties cròniques - PrevencióCAREEFFICACYmedicine.diseasebiology.organism_classificationrespiratory tract diseases030228 respiratory systemNontuberculous mycobacteria610 Medizin und GesundheitbusinessERJ Open Research
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CT angiography for the assessment of EVAR complications : a pictorial review

2022

Aortic aneurysm; Blood vessel prosthesis implantation; Endovascular procedures Aneurisma aórtico; Implantación de prótesis de vasos sanguíneos; Procedimientos endovasculares Aneurisma aòrtic; Implantació de pròtesis de vasos sanguinis; Procediments endovasculars Endovascular aneurysm repair (EVAR) is a minimally invasive treatment proposed as an alternative to open repair in patients with abdominal aortic aneurysms. EVAR consists in a stent-graft placement within the aorta in order to exclude the aneurysm from arterial circulation and reduce the risk of rupture. Knowledge of the various types of devices is mandatory because some stents/grafts are more frequently associated with complication…

:intervenciones quirúrgicas::procedimientos quirúrgicos cardiovasculares::procedimientos quirúrgicos vasculares::procedimientos endovasculares [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]:Cardiovascular Diseases::Vascular Diseases::Aneurysm::Aortic Aneurysm::Aortic Aneurysm Abdominal [DISEASES]Aortic aneurysmR895-920:diagnóstico::técnicas y procedimientos diagnósticos::diagnóstico por imagen::interpretación de imágenes asistida por ordenador::tomografía computarizada por rayos X::angiografía por tomografía computarizada [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]:Otros calificadores::Otros calificadores::/diagnóstico por imagen [Otros calificadores]:enfermedades cardiovasculares::enfermedades vasculares::aneurisma::aneurisma de la aorta::aneurisma de la aorta abdominal [ENFERMEDADES]Blood vessel prosthesis implantation:Surgical Procedures Operative::Cardiovascular Surgical Procedures::Vascular Surgical Procedures::Endovascular Procedures [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]Medical physics. Medical radiology. Nuclear medicineVasos sanguinis - CirurgiaEndovascular procedureEndovascular procedures:Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Image Interpretation Computer-Assisted::Tomography X-Ray Computed::Computed Tomography Angiography [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]cardiovascular systemRadiology Nuclear Medicine and imagingAbdominalStentsAngiografiacardiovascular diseasesComputed tomography angiography:Other subheadings::Other subheadings::/diagnostic imaging [Other subheadings]Educational ReviewAneurisma abdominal - Imatgeria
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Synthetic Polyclonal-Derived CDR Peptides as an Innovative Strategy in Glaucoma Therapy

2019

The pathogenesis of glaucoma is strongly associated with the occurrence of autoimmune-mediated loss of retinal ganglion cells (RGCs) and additionally, recent evidence shows that specific antibody-derived signature peptides are significantly differentially expressed in sera of primary-open angle glaucoma patients (POAG) compared to healthy controls. Synthetically antibody-derived peptides can modulate various effector functions of the immune system and act as antimicrobial or antiviral molecules. In an ex vivo adolescent glaucoma model, this study, for the first time, demonstrates that polyclonal-derived complementarity-determining regions (CDRs) can significantly increase the survival rate …

<i>Sus scrofa domestica</i>lcsh:MedicineRetinal ganglionEpitopeArticleSus scrofa domestica03 medical and health scienceschemistry.chemical_compound0302 clinical medicineImmune systemMedicine030304 developmental biology0303 health sciencesHTRA2synthetic CDR peptidesbusiness.industrylcsh:RautoimmunityRetinalGeneral MedicineProtein ubiquitinationCell biologyglaucomachemistryneuroprotectionSignal transductionbusinessVDAC2030217 neurology & neurosurgeryEx vivoJournal of Clinical Medicine
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Two cases of monomicrobial intraabdominal abscesses due to KPC - 3 Klebsiella pneumoniaeST258 clone

2011

Abstract Background Knowledge of the etiology of pyogenic liver and pancreatic abscesses is an important factor in determining the success of combined surgical and antibiotic treatment. Literature shows geographical variations in the prevalence and distribution of causative organisms, and the spread of Klebsiella pneumoniae carbapenemase-producing bacteria is an emerging cause of abdominal infections. Case presentation We herein describe two cases of intra-abdominal abscesses due to monomicrobial infection by Klebsiella pneumoniae Sequence Type 258 producing K. pneumoniae carbapenemase 3 (KPC-Kp). In case 1, a 50-year-old HIV-negative Italian woman with chronic pancreatitis showed infection…

<it>Klebsiellae pneumoniae</it>medicine.medical_specialtyAbdominal AbscessSettore MED/17 - Malattie Infettivecarbapenemasesmedicine.drug_classKlebsiella pneumoniaeAntibioticsMinocyclineCase ReportDrug resistanceTigecyclineTigecyclinebeta-LactamasesBacterial ProteinsDrug Resistance Multiple BacterialPancreatitis ChronicInternal medicinemedicineHumanslcsh:RC799-869Klebsiellae pneumoniaeSettore MED/12 - GastroenterologiabiologyColistinbusiness.industryAbdominal InfectionLiver NeoplasmsGastroenterologyGeneral MedicineMiddle Agedbiology.organism_classificationmedicine.diseaseAnti-Bacterial AgentsElectrophoresis Gel Pulsed-FieldKlebsiella InfectionsSurgeryPancreatic NeoplasmsSettore MED/18 - Chirurgia GeneraleKlebsiella pneumoniaeColistinPancreatitislcsh:Diseases of the digestive system. Gastroenterologymonomicrobial abscess Klebsiellae pneumoniae carbapenemasesFemalebusinessmonomicrobial abscessmedicine.drugLiver abscessBMC Gastroenterology
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MAST-RT0 SOLUTION OF 3D NAVIER STOKES EQUATIONS ON UNSTRUCTURED MESHS. PRELIMINARY RESULTS IN THE LAMINAR CASE

2021

A new numerical solver for the 3D Navier Stokes incompressible laminar problems is proposedThe governing equations are discretized over unstructured tetrahedral mesheThe proposed model is suitable for the solution of laminar flows in irregular domainsDelaunay mesh condition is not requiredSettore ICAR/01 - Idraulica
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MAST-RT0 solution of 3D Navier Stokes equations in very irregular domains. Preliminary results in the laminar case

2021

A new numerical methodology to solve the 3D Navier-Stokes equations for incompressible fluids within complex boundaries and unstructured body-fitted tetrahedral mesh is presented and validated with three literature and one real-case tests. We apply a fractional time step procedure where a predictor and a corrector problem are sequentially solved. The predictor step is solved applying the MAST (Marching in Space and Time) procedure, which explicitly handles the non-linear terms in the momentum equations, allowing numerical stability for Courant number greater than one. Correction steps are solved by a Mixed Hybrid Finite Elements discretization that assumes positive distances among tetrahedr…

A new numerical solver for the 3D Navier Stokes incompressible laminar problems is proposedThe proposed model is suitable for the solution of laminar flows in irregular domainsSettore ICAR/01 - Idraulica
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Efficacy of an internet-based psychological intervention for problem gambling and gambling disorder: study protocol for a randomized controlled trial

2021

Gambling Disorder is a prevalent non-substance use disorder, which contrasts with the low number of people requesting treatment. Information and Communication Technologies (ICT) could help to enhance the dissemination of evidence-based treatments and considerably reduce the costs. The current study seeks to assess the efficacy of an online psychological intervention for people suffering from gambling problems in Spain. The proposed study will be a two-arm, parallel-group, randomized controlled trial. A total of 134 participants (problem and pathological gamblers) will be randomly allocated to a waiting list control group (N = 67) or an intervention group (N = 67). The intervention program i…

A ActionDGOJ Directorate General for the Regulation of GamblingCIDI Composite International Diagnostic InterviewPA Positive AffectSPIRIT Standard Protocol Items Recommendations for Interventional TrialsefficacyPsychological interventionMotivational interviewingGE Gambling ExpectanciesDSM-IV Diagnostic and Statistical Manual of Mental Disorders Fourth EditionOASIS The Overall Anxiety Severity and Impairment Scalelaw.inventionDERS Difficulties in Emotion Regulation ScaleRandomized controlled triallawPANAS The Positive and Negative Affect SchedulePsychologyRCT Randomized Controlled TrialUPPS-P The Short UPPS-P Impulsivity ScaleICD-10 International Statistical Classification of Diseases and Related Health Problems 10th RevisionCognitionT58.5-58.64GRCS-S Gambling-Related Cognitions ScalePC Predictive ControlBF1-990EDBs Emotion Driven BehavioursC ContemplationGSEQ Gambling Self-Efficacy QuestionnaireDSM-5 Diagnostic and Statistical Manual of Mental Disorders Fifth EditionAnxietyAddicció a Internetmedicine.symptomMI Motivational InterviewingPsychologyJocs per ordinadorM Maintenancemedicine.medical_specialtyemotion regulationG-SAS The Gambling Symptom Assessment ScaleEMA Ecological Momentary AssessmentODSIS The Overall Depression Severity and Impairment ScaleEfficacyWL Waiting ListIC Illusion of ControlIB Interpretative BiasMFS Monitoring Feedback and SupportCBTHealth InformaticsInformation technologyCBT Cognitive Behavioral TherapyImpulsivityCONSORT-EHEALTH Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online TelehealthISG Perceived Inability to Stop GamblingQuality of life (healthcare)URICA The University of Rhode Island Change Assessment ScaleIntervention (counseling)medicineGD Gambling DisorderSCID-P The Structured Clinical InterviewPsychiatryQLI Quality Life IndexInternetEmotion regulationFull length ArticleSUS System Usability ScalegamblingEMI Ecological Momentary InterventionMINI Mini International Neuropsychiatric InterviewGI Gambling history interview and current gambling situation and related variables assessmentNA Negative AffectGamblingNODS NORC DSM-IV Screen for Gambling ProblemsPFIs Personal Feedback InterventionsDSM-III-R Diagnostic and Statistical Manual of Mental Disorders 3rd Edition RevisedHADS Hospital Anxiety Depression ScaleinternetP Precontemplation
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Abstract C75: Overcoming KRAS/LKB1 mutant NSCLC resistance to BET bromodomain inhibitors with gemcitabine or Mcl-1 inhibition

2015

Abstract The purpose of our study was to define a method and mechanism for overcoming the resistance of clinically relevant KRAS-mutant/LKB1-deficient NSCLC cells to the BET-bromodomain inhibitor JQ1. LKB1 (Serine/threonine kinase 11) is mutated with loss of function in conjunction with mutated KRAS in 7-10% of NSCLC. Importantly, KRAS-mutant/LKB1-deficiency is associated with tumor aggressiveness and poor survival in human patients as well as in genetically engineered mouse models. Indeed, although the BET bromodomain inhibitor JQ1 dramatically reduces tumor volume in KRAS mutant mice, it has little effect in KRAS-mutant/LKB1-deficient mice. BET bromodomain proteins are chromatin readers t…

A549 cellCancer ResearchGene knockdownKinaseBiologymedicine.disease_causeGemcitabineBromodomainOncologyApoptosisImmunologymedicineCancer researchOncogene MYCKRASneoplasmsmedicine.drugMolecular Cancer Therapeutics
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ABDOMINAL AORTIC ANEURYSM WALL RUPTURE RISK EVALUATION THROUGH COMPUTERIZED FINITE ELEMENT ANALYSIS MODEL AND FUZZY-TOPSIS DECISION METHOD

2008

ABDOMINAL AORTIC ANEURYSMSettore BIO/16 - Anatomia Umana
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Research update for articles published in EJCI in 2016

2018

The association of an excessive blood pressure increase with exercise (i.e., an increase in systolic blood pressure with exercise ≥95th percentile) with lower risk of subsequent events in patients with known or suspected coronary artery disease has been consistently verified even in those with baseline hypertension. Nonetheless, this negative association, also confirmed in another study on a Japanese population, might depend on peak VO2, such that the prognostic value of blood pressure response might be limited in patients with preserved exercise capacity. In addition, a hypertensive response with exercise (defined as a systolic blood pressure ≥220 mmHg during the test) has also been associ…

ABDOMINAL AORTIC-ANEURYSMGENERAL-POPULATIONADVANCED HEART-FAILURE2016Clinical BiochemistryEJCIBLOOD-PRESSUREDIABETES-MELLITUSGeneral MedicineBiochemistryMaratónTratamiento médicoMYOCARDIAL-INFARCTIONCARDIOVASCULAR-DISEASEAtletaHipertensiónCORONARY-ARTERY-DISEASEEcocardiografíaBONE-MINERAL DENSITYENDOTHELIN RECEPTOR BLOCKADESistema cardiovascular
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