Search results for "DOMAIN"

Radiation effects on optical frequency domain reflectometry fiber-based sensor

2015

International audience; We investigate the radiation effects on germanosilicate optical fiber acting as the sensing element of optical frequency domain reflectometry devices. Thanks to a new setup permitting to control temperature during irradiation, we evaluate the changes induced by 10 keV x rays on their Rayleigh response up to 1 MGy in a temperature range from −40°C up to 75°C. Irradiation at fixed temperature points out that its measure is reliable during both irradiation and the recovery process. Mixed temperature and radiation measurements show that changing irradiation temperature leads to an error in distributed measurements that depends on the calibration procedure. These results …

Intramolecular electron transfer between molybdenum and iron mimicking bacterial sulphite dehydrogenase

2014

Diferrocenyl/diferrocenium substituted dioxido molybdenum(VI) complexes [Fe2MoO2] 2(Fc)/[2(FC)]²⁺ mimic the catalytic active site including the redox subunits as well as the catalytic function of bacterial sulphite oxidases.

A PAS domain with an oxygen labile [4Fe-4S](2+) cluster in the oxygen sensor kinase NreB of Staphylococcus carnosus.

2008

The cytoplasmic histidine sensor kinase NreB of Staphylococcus carnosus responds to O(2) and controls together with the response regulator NreC the expression of genes of nitrate/nitrite respiration. nreBC homologous genes were found in Staphylococcus strains and Bacillus clausii, and a modified form was found in some Lactobacillus strains. NreB contains a sensory domain with similarity to heme B binding PAS domains. Anaerobically prepared NreB of S. carnosus exhibited a (diamagnetic) [4Fe-4S](2+) cluster when assessed by Mossbauer spectroscopy. Upon reaction with air, the cluster was degraded with a half-life of approximately 2.5 min. No significant amounts of Mossbauer or EPR detectable i…

A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase

2018

Scientific reports 8(1), 13104 (2018). doi:10.1038/s41598-018-31259-y

Defining Complexity Factors for the Architecture Evaluation Framework

2006

The design and implementation of telecommunication systems is an incremental and iterative process, and system architectures may need to be revised and refined several times during their lifetime. Formal evaluation facilitates the identification of the weak points, where improvements are due in these architectures. In the domain of telecommunications, such evaluation can be based on the Architecture Evaluation Framework (AEF). During the evaluation, a deep understanding of the processes within a system is needed. Meanwhile, the systems being designed are usually complex systems encompassing a large number of components with an intricate pattern of interaction between them. As a result, it i…

On the convergence of fixed point iterations for the moving geometry in a fluid-structure interaction problem

2019

In this paper a fluid-structure interaction problem for the incompressible Newtonian fluid is studied. We prove the convergence of an iterative process with respect to the computational domain geometry. In our previous works on numerical approximation of similar problems we refer this approach as the global iterative method. This iterative approach can be understood as a linearization of the so-called geometric nonlinearity of the underlying model. The proof of the convergence is based on the Banach fixed point argument, where the contractivity of the corresponding mapping is shown due to the continuous dependence of the weak solution on the given domain deformation. This estimate is obtain…

Wavelet-like bases for thin-wire integral equations in electromagnetics

2005

AbstractIn this paper, wavelets are used in solving, by the method of moments, a modified version of the thin-wire electric field integral equation, in frequency domain. The time domain electromagnetic quantities, are obtained by using the inverse discrete fast Fourier transform. The retarded scalar electric and vector magnetic potentials are employed in order to obtain the integral formulation. The discretized model generated by applying the direct method of moments via point-matching procedure, results in a linear system with a dense matrix which have to be solved for each frequency of the Fourier spectrum of the time domain impressed source. Therefore, orthogonal wavelet-like basis trans…

Spin torques and magnetic texture dynamics driven by the supercurrent in superconductor/ferromagnet structures

2018

We introduce the general formalism to describe spin torques induced by the supercurrents injected from the adjacent superconducting electrodes into the spin-textured ferromagnets. By considering the adiabatic limit for the equal-spin superconducting correlations in the ferromagnet we show that the supercurrent can generate both the field-like spin transfer torque and the spin-orbital torque. These dissipationless spin torques are expressed through the current-induced corrections to the effective field derived from the system energy. The general formalism is applied to show that the supercurrent can either shift or move the magnetic domain walls depending on their structure and the type of s…

Cigarette smoke affects the onco-suppressor DAB2IP expression in bronchial epithelial cells of COPD patients

2019

AbstractCigarette smoke is a risk factor for COPD and lung cancer. In cancer, epigenetic modifications affect the expression of Enhancer of Zester Homolog 2 (EZH2), and silenced disabled homolog 2 interacting protein gene (DAB2IP) (onco-suppressor gene) by Histone H3 tri-methylation in lysine 27 (H3K27me3). In“ex vivo”studies, we assessed EZH2, H3K27me3 and DAB2IP immunoreactivity in bronchial epithelial cells from COPD patients (smokers, ex-smokers), Smoker and control subjects. In“in vitro” experiments we studied the effect of cigarette smoke extract (CSE) on EZH2/H3K27me3/DAB2IP expression, apoptosis, invasiveness, and vimentin expression in 16HBE, primary cells, and lung cancer cell lin…

2018

Oncogenic human papillomaviruses (HPV) are small DNA viruses that infect keratinocytes. After HPV binding to cell surface receptors, a cascade of molecular interactions mediates the infectious cellular internalization of virus particles. Aside from the virus itself, important molecular players involved in virus entry include the tetraspanin CD151 and the epidermal growth factor receptor (EGFR). To date, it is unknown how these components are coordinated in space and time. Here, we studied plasma membrane dynamics of CD151 and EGFR and the HPV16 capsid during the early phase of infection. We find that the proteinase ADAM17 activates the extracellular signal-regulated kinases (ERK1/2) pathway…