A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase

6533b7ddfe1ef96bd127539b

RESEARCH PRODUCT

A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase

Jürgen Gauss Gregor Diezemann Theis Sommer Michele Cascella Michael Etzerodt Lalita Uribe J. Preben Morth Kaare Bjerregaard-andersen

subject

Isatin Models Molecular 0301 basic medicine Stereochemistry Glutamine lcsh:Medicine 010402 general chemistry 01 natural sciences Article Amidohydrolases Catalysis Evolution Molecular 03 medical and health sciences chemistry.chemical_compound Bacterial Proteins Catalytic Domain Hydrolase Catalytic triad Amino Acid Sequence Rhodobacteraceae lcsh:Science Conserved Sequence Kynurenine chemistry.chemical_classification Manganese Multidisciplinary biology Amidohydrolase Hydrolysis Isatin lcsh:R Active site 600 0104 chemical sciences Zinc 030104 developmental biology Enzyme chemistry Biocatalysis Arylformamidase Biocatalysis biology.protein Quantum Theory lcsh:Q Protons ddc:600

description

Scientific reports 8(1), 13104 (2018). doi:10.1038/s41598-018-31259-y

year	journal	country	edition	language
2018-08-30

10.1038/s41598-018-31259-y https://orbit.dtu.dk/en/publications/c634c7f3-959f-4051-a7e5-5fdba7981f9c

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