Search results for "DOP"
showing 10 items of 4870 documents
Incidence du passage obligatoire aux normes comptables IAS / IFRS sur le risque d'instabilité bancaire
2011
In this thesis, we study the economic consequences, in terms of instability, of the mandatory IAS/IFRS adoption in the banking industry. The thesis is organized as follows. In a first part (Chapter I), we develop a theoretical framework whose purpose is to understand the mechanisms through which the mandatory IAS/IFRS adoption by banks may influence the probability of occurrence of a banking crisis. At this stage, we show that several arguments, derived from the contractual and informational perspectives of accounting, can be mobilized in order to justify the hypothesis that the mandatory IAS/IFRS adoption has a positive or a negative influence on banking stability. The second part of the t…
I rivestimenti marmorei nelle facciate del dopoguerra: dall'analisi tecnologica alla riqualificazione
2015
Il presente contributo intende analizzare le ragioni culturali e le caratteristiche tecnologiche dei rivestimenti marmorei delle facciate delle architetture realizzate in massima parte tra le due guerre, ma in alcuni casi anche nell’immediato secondo dopoguerra, al fine di proporre una soluzione innovativa e sostenibile per un loro recupero. Dopo avere brevemente analizzato le tipologie di queste architetture monumentali nel panorama nazionale, destinate nella maggior parte dei casi a funzioni pubbliche rappresentative, che affondano le loro radici culturali nelle ragioni delle architetture di regime, si procederà ad un esame delle differenti modalità di posa in opera dei rivestimenti marmo…
The Continued Innovation-Decision Process : A Case Study of Continued Adoption of Robotic Process Automation
2022
Robotic Process Automation (RPA) originally entered the field of information systems as one of those disruptive innovations that will, among other automation solutions, have a profound effect on job descriptions and work itself in near future. One of the sectors that will be revolutionized – and are in fact already changing – are financial and human resource (HR) services, such as accounting, billing, and payroll services. According to statistics, Finnish companies operating on the administrative and support services sector make little use of service robots. Companies that have initially adopted the technology do not necessary reach its full potential. We explore what factors create challen…
Buccal delivery as a new challenge for treatment of motor fluctuations in Parkinson's Disease
2011
Ultrafast optics in coherently spinning molecules
2020
This thesis reports on the study of unidirectional rotation of molecules and focuses on the rotational Doppler effect occuring in the course of third-harmonic generation in coherently spinning molecules.The rotational Doppler effect appears when a circularly polarized wave interacts with an anisotropic rotating object. During the interaction, an exchange of angular momentum and energy between the field and the object occurs, leading to a frequency shift of the wave. In this work, the frequency shift of the third-harmonic generated in unidirectionaly rotating molecules has been observed. An anlytical model developped in the mansucript forsees four kinds of frequency shifts depending on the m…
Crystallization and Preliminary X-Ray Analysis of Rotavirus Protein VP6
1998
ABSTRACT As a first step to gain insight into the structure of the rotavirus virion at atomic resolution, we report here the expression, purification, and crystallization of recombinant rotavirus protein VP6. This protein has the property of polymerizing in the form of tubular structures in solution which have hindered crystallization thus far. Using a combination of electron microscopy and small-angle X-ray scattering, we found that addition of Ca 2+ at concentrations higher than 100 mM results in depolymerization of the tubes, leading to an essentially monodisperse solution of trimeric VP6 even at high protein concentrations (higher than 10 mg/ml), thereby enabling us to search for crysta…
Highly textured boron/nitrogen co-doped TiO2 with honeycomb structure showing enhanced visible-light photoelectrocatalytic activity
2020
International audience; In this work, we report a novel photocatalyst based on boron and nitrogen co-doped TiO2 rutile (1 1 0) honeycomb structures. The photocatalyst has been prepared by simultaneously oxidizing and doping a Ti-foil substrate at 750 degrees C. The unit cell volume and the crystallite size of grown TiO2 films were measured by Rietveld refinement analysis. The co-doping by boron and nitrogen was achieved simultaneously with the oxidation of the titanium, resulting in a rutile (1 1 0) textured TiO2 film. X-ray photoelectron spectroscopy analysis revealed the presence of Ti-O-N and Ti-O-B-N bonds, and the presence of crystal defects in the lattice was detected and displayed by…
Targeting SARS-CoV-2 Main Protease for Treatment of COVID-19: Covalent Inhibitors Structure-Activity Relationship Insights and Evolution Perspectives
2022
The viral main protease is one of the most attractive targets among all key enzymes involved in the SARS-CoV-2 life cycle. Covalent inhibition of the cysteine145 of SARS-CoV-2 MPRO with selective antiviral drugs will arrest the replication process of the virus without affecting human catalytic pathways. In this Perspective, we analyzed the in silico, in vitro, and in vivo data of the most representative examples of covalent SARS-CoV-2 MPRO inhibitors reported in the literature to date. In particular, the studied molecules were classified into eight different categories according to their reactive electrophilic warheads, highlighting the differences between their reversible/irreversible mech…
Dopamine antagonists impair ‘red-green’ discrimination in goldfish after intravitreal injection
1995
Color vision in goldfish is tetrachromatic. However, under mesopic illumination conditions the L-cones do not contribute to wavelength discrimination, and color vision becomes trichromatic. To investigate the role of dopamine in light adaptation, we tested the effect of the unspecific dopamine antagonist haloperidol and of the specific dopamine Dl receptor antagonists SCH 23390 and SKF 83566-biotinyl in behavioral wavelength discrimination experiments. After injection of dopamine antagonists into the vitreous, a reduction in wavelength discrimination was observed in the range between 560 nm and 630 nm but not in the range between 404 nm and 501 nm.
Synergistic effects of childhood adversity and polygenic risk in first-episode psychosis
2023
The European Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI) Project is funded by grant agreement HEALTH-F2-2010-241909 (Project EU-GEI) from the European Community’s Seventh Framework Programme.