Search results for "DOP"
showing 10 items of 4870 documents
The “green” electrochemical synthesis of periodate
2020
Abstract High‐grade periodate is relatively expensive, but is required for many sensitive applications such as the synthesis of active pharmaceutical ingredients. These high costs originate from using lead dioxide anodes in contemporary electrochemical methods and from expensive starting materials. A direct and cost‐efficient electrochemical synthesis of periodate from iodide, which is less costly and relies on a readily available starting material, is reported. The oxidation is conducted at boron‐doped diamond anodes, which are durable, metal‐free, and nontoxic. The avoidance of lead dioxide ultimately lowers the cost of purification and quality assurance. The electrolytic process was opti…
Electrochemical C−H Functionalization of (Hetero)Arenes—Optimized by DoE
2020
Abstract A novel approach towards the activation of different arenes and purines including caffeine and theophylline is presented. The simple, safe and scalable electrochemical synthesis of 1,1,1,3,3,3‐hexafluoroisopropanol (HFIP) aryl ethers was conducted using an easy electrolysis setup with boron‐doped diamond (BDD) electrodes. Good yields up to 59 % were achieved. Triethylamine was used as a base as it forms a highly conductive media with HFIP, making additional supporting electrolytes superfluous. The synthesis was optimized using Design of Experiment (DoE) techniques giving a detailed insight to the significance of the reaction parameters. The mechanism was investigated by cyclic volt…
Direct electrochemical generation of organic carbonates by dehydrogenative coupling.
2018
Organic carbonates are an important source for polycarbonate synthesis. However, their synthesis generally requires phosgene, sophisticated catalysts, harsh reaction conditions, or other highly reactive chemicals. We present the first direct electrochemical generation of mesityl methyl carbonate by C–H activation. Although this reaction pathway is still challenging concerning scope and efficiency, it outlines a new strategy for carbonate generation.
Understanding brand strategy adoption by high tech SME managers
2014
Brukeradopsjon av ACOS Individuell plan hos plankoordinatorene : En studie med kombinerte metoder om påvirkningsfaktorer for plankoordinatorenes bruk…
2018
Masteroppgave i helse- og sosialinformatikk HSI500 - Universitetet i Agder 2018 Individual care plan is a comprehensive plan to assist users in need of long-term and coordinated services. Individual care plan is one of several service areas in the municipality digitized for better flow of work procedures, lower costs and increased user involvement. The ACOS IP program enables electronic IP in the municipalities. The study has investigated which main factors affect the plan coordinators user adoption of ACOS IP. User adoption looks at why and how a program is used. The purpose is to look at it from the plan coordinator's perspective, but also how the management at the coordinating unit's fra…
Improved superresolution in coherent optical systems.
2001
Objects that temporally vary slowly can be superresolved by the use of two synchronized moving masks such as pinholes or gratings. This approach to superresolution allows one to exceed Abbe’s limit of resolution. Moreover, under coherent illumination, superresolution requires a certain approximation based on the time averaging of intensity rather than of field distribution. When extensive digital postprocessing can be incorporated into the optical system, a detector array and some postprocessing algorithms can replace the grating that is responsible for information decoding. In this way, no approximation is needed and the synchronization that is necessary when two gratings are used is simpl…
How to start with big data - a multiple case study
2018
Superresolving optical system with time multiplexing and computer decoding
2008
Objects that have slow temporal variations may be superresolved with two moving masks such as pinhole or grating. The first mask is responsible for encoding the input image, and the second one performs the decoding operation. This approach is efficient for exceeding the resolving capability beyond Abbe’s limit of resolution. However, the proposed setup requires two physical gratings that should move in a synchronized manner. We propose what is believed to be a novel configuration in which the second grating responsible for the information decoding is replaced with a detector array and some postprocessing digital procedures. In this way the synchronization problem that exists when two gratin…
Benigne Form der Osteopetrose
2001
Die Osteopetrose ist eine Erkrankung, bei der es zu Resorptionsstorungen des durch enchondrale Ossifikation gebildeten Knochens kommt. Die Ursache der Osteoklasteninsuffizienz ist nicht bekannt. In der Literatur wird ein vollstandiger Syntheseverlust der Zysteinprotease Kathepsin K als Atiologie der Resorptionsstorung diskutiert. Wir konnten in unserem Fallbericht bei der benignen Form der Osteopetrose eine Kathepsin-K-Expression osteoklastarer Zellen nachweisen. Weiterhin fanden wir in den osteoklastaren Zellen den Makrophagenmarker CD68, wobei sich in deren Nachbarschaft keine weiteren Zellen des mononuklearen Phagozytensystems darstellen liesen. Eine Hemmung der osteoklastaren Zellen dur…
Serotonin–dopamine interaction: an overview
2008
Central serotonergic and dopaminergic systems play a critical role in the regulation of normal and abnormal behaviours. Moreover, recent evidence suggests that the dysfunction of dopamine (DA) and serotonin (5-hydroxytriptamine, 5-HT) neurotransmission might underlie the pathophysiology of neuropsychiatric disorders, including depression, schizophrenia, attention deficit hyperactivity disorders, drug abuse, Gilles de la Tourette's syndrome and Parkinson's disease.