Search results for "DOT"

Korkeakouluopiskelijoiden vuorovaikutusosaaminen kollaboratiivisessa ryhmässä case Demola

2009

A Polyphenylene Dendrimer Drug Transporter with Precisely Positioned Amphiphilic Surface Patches

2014

The design and synthesis of a polyphenylene dendrimer (PPD 3) with discrete binding sites for lipophilic guest molecules and characteristic surface patterns is presented. Its semi-rigidity in combination with a precise positioning of hydrophilic and hydrophobic groups at the periphery yields a refined architecture with lipophilic binding pockets that accommodate defined numbers of biologically relevant guest molecules such as fatty acids or the drug doxorubicin. The size, architecture, and surface textures allow to even penetrate brain endothelial cells that are a major component of the extremely tight blood-brain barrier. In addition, low to no toxicity is observed in in vivo studies using…

Role of nitric oxide and nitric oxide synthases in experimental models of denervation and reinnervation.

2001

Nitric oxide (NO) is a short-living free molecule synthesized by three different isoforms of nitric oxide synthases (NOS)—neuronal NOS, endothelial NOS, and inducible NOS—associated with neuromuscular transmission, muscle contractility, mitochondrial respiration, and carbohydrate metabolism in skeletal muscle. Neuronal NOS is constitutively expressed at the muscle fiber sarcolemma linked to the dystrophin-glycoprotein complex and concentrated at the neuromuscular endplate. There is increasing evidence that altered expression of neuronal NOS plays a role in muscle fiber damage in neuromuscular diseases such as dystrophinopathies and denervating disorders. Although there have been some previo…

Continuous-Variable Tomography of Solitary Electrons

2019

A method for characterising the wave-function of freely-propagating particles would provide a useful tool for developing quantum-information technologies with single electronic excitations. Previous continuous-variable quantum tomography techniques developed to analyse electronic excitations in the energy-time domain have been limited to energies close to the Fermi level. We show that a wide-band tomography of single-particle distributions is possible using energy-time filtering and that the Wigner representation of the mixed-state density matrix can be reconstructed for solitary electrons emitted by an on-demand single-electron source. These are highly localised distributions, isolated fro…

Unconventional Fluorescence Quenching in Naphthalimide-Capped CdSe/ZnS Nanoparticles

2013

Core–shell (CS) CdSe/ZnS quantum dots (QD) capped with ligands that possess a mercapto or an amino group and a naphthalimide (NI) as chromophore unit, linked by a short ethylene chain (CS@S–NI and CS@H2N–NI, respectively), have been synthesized and fully characterized by infrared and nuclear magnetic resonance spectroscopies, high-resolution transmission electron microscopy, and voltammetry as well as by steady-state absorption and emission spectroscopies. The organic ligands HS–NI and H2N–NI act as bidentate ligands, thereby causing a drastic decrease in the QD emission. This was particularly evident in the case of CS@S–NI. This behavior has been compared with that of commercially availabl…

Teacher ability evaluation and changes in elementary student profiles of motivation and performance in mathematics

2018

Abstract The aim of this person-centered study is to identify the profiles of interest value, self-concept, and performance in the domain of mathematics among elementary school students and to examine the stability and changes in these profiles from grade 1 to grade 2. Teacher-reported evaluations of students' mathematical ability and gender were examined as predictors of changes in the student profiles. The sample consisted of 237 students (46.8% girls). The latent profile analysis identified four profiles: 1) low levels of interest value, medium levels of self-concept and performance; 2) low levels of interest value, self-concept and performance; 3) high levels of interest value, self-con…

Entanglement dynamics of two independent cavity-embedded quantum dots

2010

We investigate the dynamical behavior of entanglement in a system made by two solid-state emitters, as two quantum dots, embedded in two separated micro-cavities. In these solid-state systems, in addition to the coupling with the cavity mode, the emitter is coupled to a continuum of leaky modes providing additional losses and it is also subject to a phonon-induced pure dephasing mechanism. We model this physical configuration as a multipartite system composed by two independent parts each containing a qubit embedded in a single-mode cavity, exposed to cavity losses, spontaneous emission and pure dephasing. We study the time evolution of entanglement of this multipartite open system finally …

Indoor air quality in schools of a highly polluted south Mediterranean area

2019

This study aimed at surveying lower secondary schools in southern Italy, in a highly polluted area. A community close to an industrial area and three villages in rural areas was investigated. Indoor temperature, relative humidity (RH), gaseous pollutants (CO 2 and NO 2 ), selected biological pollutants in indoor dust, and the indoor/outdoor mass concentration and elemental composition of PM 2.5 were ascertained. Temperature and RH were within, or close to, the comfort range, while CO 2 frequently exceeded the threshold of 1000 ppm, indicating inadequate air exchange rate. In all the classrooms, median NO 2 levels were above the WHO threshold value. Dermatophagoides p. allergen concentration…

Introduzione

2017

Nella cornice del Piano Colore Isole Egadi, il convegno internazionale “Identity | The Colors of Project” evidenzia il ruolo strategico dell’identità – di un’istituzione, di un’azienda, di un territorio – con particolare riferimento alle connotazioni identificative del colore. Qui, studiosi con competenze disciplinari diverse si confrontano sul tema spaziando in ambiti molto diversi: dal prodotto al cibo, dal web al car design, dalla fotografia alla brand identity.

Flaviano Celaschi, Non industrial design. Contributi al discorso progettuale, Luca Sossella Editore, Vignate (MI), 2016

2017

È un’analisi attenta e molto attuale, quella di Flaviano Celaschi, sulla figura del designer e sul design: una disciplina che mai come in questo momento ha goduto di consenso e di attenzione nella società contemporanea, non di un’accolita di esperti e annoiati analisti o professionisti del progetto, ma della società intesa come un “noi plurale ed esteso”. Ciò accade perché il design è una disciplina che va affiancata: chi sa solo di design non sa niente di design è l’anonima citazione che introduce il libro. Nelle prime pagine, introducendo il discorso progettale contemporaneo, Celaschi offre una bella definizione di design: è il nome che diamo all’esigenza dell’uomo contemporaneo di modifi…