Search results for "Database"

showing 10 items of 2136 documents

Recent Developments in Quantum Algorithms and Complexity

2014

We survey several recent developments in quantum algorithms and complexity: Reichardt’s characterization of quantum query algorithms via span programs [15]; New bounds on the number of queries that are necessary for simulating a quantum algorithm that makes a very small number of queries [2]; Exact quantum algorithms with superlinear advantage over the best classical algorithm [4].

Quantum queryComputer scienceSmall number0102 computer and information sciences02 engineering and technologySpan (engineering)01 natural sciences010201 computation theory & mathematicsComputerSystemsOrganization_MISCELLANEOUS020204 information systems0202 electrical engineering electronic engineering information engineeringQuantum algorithmBoolean functionAlgorithmComputer Science::DatabasesDescriptional Complexity of Formal Systems (16th International Workshop, DCFS 2014)
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Ultrametric Vs. Quantum Query Algorithms

2014

Ultrametric algorithms are similar to probabilistic algorithms but they describe the degree of indeterminism by p-adic numbers instead of real numbers. This paper introduces the notion of ultrametric query algorithms and shows an example of advantages of ultrametric query algorithms over deterministic, probabilistic and quantum query algorithms.

Quantum queryDegree (graph theory)Computer scienceComputer Science::Information RetrievalProbabilistic logicMathematics::General TopologyCondensed Matter::Disordered Systems and Neural NetworksIndeterminismMathematics::Metric GeometryProbabilistic analysis of algorithmsQuantum algorithmAlgorithmUltrametric spaceComputer Science::DatabasesMathematicsofComputing_DISCRETEMATHEMATICSReal number
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Quantum versus classical query complexity of relation

2011

This paper investigates the computability of mathematical relations in a quantum query model. The important task in complexity theory is to find examples with a large gap between classical and quantum algorithm complexity of the same computational problem. We present new results in quantum query algorithm design that allow achieving a large separation between classical and quantum query complexity of a specific relation. We demonstrate an example where quantum query algorithm for a finite relation needs more than two times fewer queries than the best possible classical analogue. We also show that relation can be extended to infinite family of relations with an input of general size N.

Quantum sortTheoretical computer scienceQuantum phase estimation algorithmSimon's problemQuantum algorithmQuantum informationQuery optimizationComputer Science::DatabasesQuantum complexity theoryQuantum computerMathematics2011 Seventh International Conference on Natural Computation
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"Table 22" of "Freeze-out radii extracted from three-pion cumulants in pp, p-Pb and Pb-Pb collisions at the LHC"

2014

Exponential radii scaled down by sqrt(pi) and intercept parameters in PbPb collisions versus Nch at low KT3.

R lambdaInclusiveMathematics::Algebraic Geometry2760.0Physics::Instrumentation and DetectorsPB PB --> PI+ XNuclear ExperimentPB PB --> PI- XMathematics::Geometric TopologyComputer Science::Databases
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"Table 25" of "Freeze-out radii extracted from three-pion cumulants in pp, p-Pb and Pb-Pb collisions at the LHC"

2014

Exponential radii scaled down by sqrt(pi) and intercept parameters in PbPb collisions versus Nch at high KT3.

R lambdaInclusiveMathematics::Algebraic Geometry2760.0Physics::Instrumentation and DetectorsPB PB --> PI+ XNuclear ExperimentPB PB --> PI- XMathematics::Geometric TopologyComputer Science::Databases
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"Table 20" of "Freeze-out radii extracted from three-pion cumulants in pp, p-Pb and Pb-Pb collisions at the LHC"

2014

Exponential radii scaled down by sqrt(pi) and intercept parameters in pp collisions versus Nch at low KT3.

R lambdaInclusiveMathematics::Algebraic GeometryProton-Proton Scattering7000.0P P --> PI+ XNuclear ExperimentP P --> PI- XMathematics::Geometric TopologyComputer Science::Databases
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"Table 23" of "Freeze-out radii extracted from three-pion cumulants in pp, p-Pb and Pb-Pb collisions at the LHC"

2014

Exponential radii scaled down by sqrt(pi) and intercept parameters in pp collisions versus Nch at high KT3.

R lambdaInclusiveMathematics::Algebraic GeometryProton-Proton Scattering7000.0P P --> PI+ XNuclear ExperimentP P --> PI- XMathematics::Geometric TopologyComputer Science::Databases
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Genome-wide significant association of ANKRD55 rs6859219 and multiple sclerosis risk.

2013

Multiple sclerosis (MS) is a genetically complex disease that shares a substantial proportion of risk loci with other autoimmune diseases.1 Along these lines, ANKRD55 , originally implicated in rheumatoid arthritis, was recently reported as a potential novel MS risk gene (rs6859219, p=1.9×10−7).2 Here, we comprehensively validated this effect in independent datasets comprising 8846 newly genotyped subjects from Germany and France as well as 5003 subjects from two genome-wide association studies (GWAS). Upon meta-analysis of all available data (19 686 subjects), ANKRD55 rs6859219 now shows compelling evidence for association with MS at genome-wide significance (OR=1.19, p=3.1×10−11). Our stu…

RFXANKAdultMalemedicine.medical_specialtyMultiple SclerosisLocus (genetics)Genome-wide association studySingle-nucleotide polymorphismBiologyPolymorphism Single NucleotideWhite PeopleMolecular geneticsDatabases GeneticGeneticsmedicineHumansGenetic Predisposition to DiseaseGenetics (clinical)Genetic associationGeneticsMultiple sclerosisMiddle Agedmedicine.diseaseAnkyrin RepeatCase-Control StudiesAnkyrin repeatFemaleCarrier ProteinsGenome-Wide Association StudyJournal of medical genetics
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The Concise Guide To Pharmacology 2021/22: G Protein-Coupled Receptors

2021

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will s…

RMCytoplasmic and NuclearComputer scienceDatabases PharmaceuticalHumans; Ion Channels; Ligands; Receptors Cytoplasmic and Nuclear; Receptors G-Protein-Coupled; Databases Pharmaceutical; PharmacologyReceptors Cytoplasmic and NuclearIN-VITRO CHARACTERIZATIONPharmacologyLigandsIon ChannelsNORSlaw.inventionReceptors G-Protein-CoupledG-Protein-CoupledDatabases03 medical and health sciencesCALCIUM-SENSING RECEPTOR0302 clinical medicineDELTA-OPIOID RECEPTORlawSummary informationReceptorsHumansHISTAMINE H-3 RECEPTORFATTY-ACID RECEPTORMETABOTROPIC GLUTAMATE-RECEPTOR030304 developmental biologyG protein-coupled receptorPharmacologyGONADOTROPIN-RELEASING-HORMONE0303 health sciencesClinical pharmacologyFORMYL PEPTIDE RECEPTORMUSCARINIC ACETYLCHOLINE-RECEPTOR3. Good health317 Pharmacy030220 oncology & carcinogenesisPharmaceuticalNEGATIVE ALLOSTERIC MODULATORCatalytic receptors
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Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates

2021

Due to the widespread of the COVID-19 pandemic, the SARS-CoV-2 genome is evolving in diverse human populations. Several studies already reported different strains and an increase in the mutation rate. Particularly, mutations in SARS-CoV-2 spike-glycoprotein are of great interest as it mediates infection in human and recently approved mRNA vaccines are designed to induce immune responses against it. We analyzed 1,036,030 SARS-CoV-2 genome assemblies and 30,806 NGS datasets from GISAID and European Nucleotide Archive (ENA) focusing on non-synonymous mutations in the spike protein. Only around 2.5% of the samples contained the wild-type spike protein with no variation from the reference. Among…

RNA virusesMutation rateCoronavirusesEpidemiologyMolecular biologyT-LymphocytesMutantGene Identification and Analysismedicine.disease_causeGenomeWhite Blood CellsDatabase and Informatics MethodsSequencing techniquesMutation RateAnimal CellsDNA sequencingPathology and laboratory medicineGeneticsMutationMultidisciplinaryT CellsMicrobial MutationQRHigh-Throughput Nucleotide SequencingGenomicsMedical microbiologyVirusesSpike Glycoprotein CoronavirusMedicineSARS CoV 2PathogensCellular TypesTranscriptome AnalysisSequence AnalysisResearch ArticleNext-Generation SequencingSARS coronavirusBioinformaticsImmune CellsScienceImmunologyProtein domainSequence alignmentGenomicsGenome ViralBiologyMicrobiologyAntibodiesDNA sequencingProtein DomainsGeneticsmedicineHumansMutation DetectionPandemicsMedicine and health sciencesBlood CellsBiology and life sciencesSARS-CoV-2OrganismsViral pathogensComputational BiologyCOVID-19Cell BiologyGenome AnalysisMicrobial pathogensResearch and analysis methodsMolecular biology techniquesMutationSequence AlignmentPLOS ONE
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