Search results for "Databases"

showing 10 items of 937 documents

Obstructive sleep apnoea independently predicts lipid levels: Data from the European Sleep Apnea Database

2018

Background and objective: Obstructive sleep apnoea (OSA) and dyslipidaemia are independent risk factors for cardiovascular disease. This study investigates the association between OSA and plasma lipid concentrations in patients enrolled in the European Sleep Apnea Database (ESADA) cohort. Methods: The cross-sectional analysis included 8592 patients without physician-diagnosed hyperlipidaemia or reported intake of a lipid-lowering drug (age 50.1 ± 12.7 years, 69.1% male, BMI: 30.8 ± 6.6 kg/m2, mean apnoea–hypopnoea index (AHI): 25.7 ± 25.9 events/h). The independent relationship between measures of OSA (AHI, oxygen desaturation index (ODI), mean and lowest oxygen saturation) and lipid profil…

MaleobesityDatabases Factualcholesterol dyslipidemia hypoxia obesity sleep apnoeaGastroenterologyCohort Studieschemistry.chemical_compound0302 clinical medicineRisk FactorsHypolipidemic AgentsOxygen saturation (medicine)Sleep Apnea Obstructivemedicine.diagnostic_testSleep apneaMiddle AgedEuropeQuartileCardiovascular DiseasesCohortFemalelipids (amino acids peptides and proteins)AdultPulmonary and Respiratory Medicinemedicine.medical_specialtySettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesInternal medicinemedicineHumansTriglyceridesDyslipidemiashypoxiaCholesterolbusiness.industryCholesterol HDLdyslipidemiacholesterolCholesterol LDLta3121medicine.diseaseObesitynervous system diseasesrespiratory tract diseasesCross-Sectional Studies030228 respiratory systemchemistryLipid profilebusinesssleep apnoea030217 neurology & neurosurgeryDyslipidemiaRespirology
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Cancer prevalence is increased in females with sleep apnoea: data from the ESADA study

2019

[No abstract available]

MaleobesityLetterDatabases FactualDownload[SDV]Life Sciences [q-bio]cigarette smokingPolysomnographycancer riskdisease burdenapnea hypopnea indexsleep disordered breathingstudy design0302 clinical medicinepolysomnographyRisk FactorsNothingcancer diagnosisNeoplasmsmiddle agedgenderPrevalence030212 general & internal medicineSleep studyobstructive sleep apneaSleep Apnea Obstructiveeducation.field_of_studyanthropometryquantitative analysismedicine.diagnostic_testadultrisk assessmentclinical trialcohort analysisprostate cancerpulse oximetry[SDV] Life Sciences [q-bio]Europenot availablecomorbidityagedfemalewaist hip ratiocolon cancerpriority journalrisk factorfactual databasedisease severitycerebrovascular accidentPulmonary and Respiratory Medicinemedicine.medical_specialtyalcohol consumptionintermittent hypoxiaPopulationMEDLINElymphomaSettore MED/10 - Malattie Dell'Apparato Respiratoriomalignant neoplasmcancer growth03 medical and health sciencesmelanomamedicinecancercross-sectional studyHumanscontrolled studyhumaneducationCancer prevalencehypoxiabusiness.industrystatistical modelConflict of interestpredictionmajor clinical studybody massoxygen saturationlung cancermulticenter studyCross-Sectional StudiesLogistic Modelsage030228 respiratory systemdisease severity assessmentFamily medicineoxygen desaturation indexhead and neck cancerHuman medicinebusinessneoplasmEuropean Respiratory Journal
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Time to recurrence is a significant predictor of cancer-specific survival after recurrence in patients with recurrent renal cell carcinoma - Results …

2013

Objectives To assess the prognostic impact of time to recurrence (TTR) on cancer-specific survival (CSS) after recurrence in patients with renal cell carcinoma (RCC) undergoing radical nephrectomy or nephron-sparing surgery. To analyse differences in clinical and histopathological criteria between patients with early and late recurrence. Patients and Methods Of 13 107 patients with RCC from an international multicentre database, 1712 patients developed recurrence in the follow-up (FU), at a median (interquartile range) of 50.1 (25-106) months. In all, 1402 patients had recurrence at ≤5 years (Group A) and 310 patients beyond this time (Group B). Differences in clinical and histopathological…

Malerenal cell carcinomaTime FactorsTime FactorDatabases FactualPrognosiUrologyprognostic parameterearly recurrencetime to recurrencecancer-specific survivalRetrospective Studielate recurrencenephrectomyHumanscancer survivalCarcinoma Renal Cellrenal cell carcinoma (RCC); time to recurrence; early recurrence; late recurrence; prognostic parameters; cancer-specific survival; nephrectomyAgedRetrospective StudiesKidney NeoplasmMiddle Agedprognostic parametersPrognosisKidney NeoplasmsSurvival Ratecancer survival; early recurrence; late recurrence; nephrectomy; prognostic parameters; renal cell carcinomacancer-specific survival; early recurrence; late recurrence; nephrectomy; prognostic parameters; renal cell carcinoma; time to recurrenceFemaleNeoplasm Recurrence Localrenal cell carcinoma (rcc)cancer-specific survival; early recurrence; late recurrence; nephrectomy; prognostic parameters; renal cell carcinoma (rcc); time to recurrenceHuman
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Clinical features and lifestyle of patients with amyotrophic lateral sclerosis in Campania: brief overview of an Italian database

2012

Background. Physical activity and occupational exposures appeared to play a relevant role in pathogenesis of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease of unknown origin. Materials and methods. We aimed to make an overview of the clinical characteristics and life - style (occupation and sport) of a population of 395 patients with ALS from campania, in southern Italy. Results. ALS onset resulted anticipated of about 11 years in industry workers, whilst the more frequent site of onset among farmers was upper limbs. compared to non-athletes, athletes, particu- larly soccer players, showed a 7 years anticipation of ALS onset, with higher mortality after 5 years. Discussion…

Malesclerosi laterale amiotroficaDatabases Factualesposizione occupazionaleOccupational ExposureHumansMedicineOccupationsAmyotrophic lateral sclerosisLife Styledatabase clinicoAgedLife stylebusiness.industrylcsh:Public aspects of medicineAmyotrophic Lateral SclerosisDisease progressionPublic Health Environmental and Occupational Healthlcsh:RA1-1270General MedicineMiddle Agedmedicine.diseaseItalyDisease ProgressionAmyotrophic lateral sclerosis motor neuron diseases clinical database occupational exposure.Settore MED/26 - NeurologiaFemaleOccupational exposurebusinessmalattie del motoneuroneHumanitiesSportsAnnali dell'Istituto Superiore di Sanità
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Pan-cancer analysis of whole genomes

2020

Publisher's version (útgefin grein)

Maletert promoter mutationsCancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2]DNA Mutational AnalysisNormal tissuesystematic analysisGermlineTranscriptome0302 clinical medicineAetiologyCàncerCellular SenescenceCancer0303 health sciencesdna-damageMassive parallel sequencingPan cancerREARRANGEMENTSHigh-Throughput Nucleotide SequencingGenomicsSciences bio-médicales et agricolesTelomereCOMPREHENSIVE3. Good healthTERT PROMOTER MUTATIONSsignatures030220 oncology & carcinogenesisScience & Technology - Other TopicsErfðarannsóknirHuman:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]EvolutionRNA SplicingGenomicsArticleEvolution MolecularStructural variationRC025403 medical and health sciencesSDG 3 - Good Health and Well-beingGeneticgenomicsSYSTEMATIC ANALYSISGeneticsGenomics--Databases.HumansGenetic TestingMolecular BiologySIGNATURESWhole genome sequencing1000 MultidisciplinaryChromothripsisScience & TechnologyRC0254 Neoplasms. Tumors. Oncology (including Cancer)Information DisseminationResearchInstitutes_Networks_Beacons/mcrcPreventionBiology and Life SciencesMolecularOncogenesCloud Computingmedicine.diseaseGenòmicaCompute cloudsMutation570 Life sciences; biologyCOMPREHENSIVE CHARACTERIZATIONGenèticaWhole Genome Sequencing--methodsBackground informationDNA Mutational Analysis ; Evolution ; Genetic / genetics ; Genome ; Genomics ; Germ-Line Mutation / genetics ; High-Throughput Nucleotide Sequencing ; Human / genetics ; Humans ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumMedizinGenomeWhole-genomeGenome mappingNeoplasms2.1 Biological and endogenous factorsPromoter Regions GeneticCàncer -- Aspectes genèticsTelomeraseGeneticsWomen's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17]MultidisciplinaryChromothripsisGenomeManchester Cancer Research Centregenomics cancer profiling3rd-DAS10124 Institute of Molecular Life SciencesWomen's cancers Radboud Institute for Health Sciences [Radboudumc 17]Multidisciplinary SciencesParallel sequencingICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumFemaleprofilingMedical GeneticsEngineering sciences. TechnologyBiotechnologyGeneral Science & TechnologyThe Cancer Genome Atlas610 Medicine & healthComputational biologyQH426 GeneticsBiologyConsortium of the International Cancer Genome ConsortiumPromoter RegionsGermline mutationPan-cancer analysisKrabbameinsrannsóknirmedicinecancerddc:610QH426Germ-Line MutationMedicinsk genetikKrabbamein030304 developmental biologyCell ProliferationLANDSCAPEGenome Humancomprehensive characterizationPan-cancer analysis of whole genomesPoint mutationHuman GenomeCancerReproducibility of ResultsSOMATIC MUTATIONSEVOLUTIONCancer sequencing Chromothripsis telomereDNA-DAMAGEMutagenesisPATTERNS3111 BiomedicineCHARACTERIZATION
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Formation of new genes explains lower intron density in mammalian Rhodopsin G protein-coupled receptors

2007

Mammalian G protein-coupled receptor (GPCR) genes are characterised by a large proportion of intronless genes or a lower density of introns when compared with GPCRs of invertebrates. It is unclear which mechanisms have influenced intron density in this protein family, which is one of the largest in the mammalian genomes. We used a combination of Hidden Markov Models (HMM) and BLAST searches to establish the comprehensive repertoire of Rhodopsin GPCRs from seven species and performed overall alignments and phylogenetic analysis using the maximum parsimony method for over 1400 receptors in 12 subgroups. We identified 14 different Ancestral Receptor Groups (ARGs) that have members in both vert…

MammalsGeneticsRhodopsinProtein familyIntronComputational BiologySequence alignmentGroup II intronBiologyIntronsReceptors G-Protein-CoupledEvolution MolecularPhylogeneticsRhodopsinGeneticsbiology.proteinAnimalsHumansDatabases Nucleic AcidSequence AlignmentMolecular BiologyGenePhylogenyEcology Evolution Behavior and SystematicsG protein-coupled receptorMolecular Phylogenetics and Evolution
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Spatial mapping of price competition using logit-type market share models and store-level scanner-data

2009

This paper proposes a methodology to obtain reliable spatial maps of price competition using store-level scanner data. Specifically, a procedure to obtain a symmetric matrix of similarities between brands considering their substitutability depending on price variations is proposed. The matrix is derived from a market response model where price cross-effects are split into two components. The first component accounts for the fact that price variation in one brand can have different effects to price variation in other brands (ie j → j′≠j′ → j). The second component accounts for the fact that the price of each brand can have different effects across competing brands (ie j → j′≠j → j ″). The ma…

MarketingInventory controlCross elasticity of demandOperations researchStrategy and Management05 social sciencesLogitManagement Science and Operations Research050105 experimental psychologyPurchasingManagement Information SystemsMarket structure0502 economics and businessEconomicsMarket priceEconometricsSymmetric matrix050211 marketing0501 psychology and cognitive sciencesMarket shareComputer Science::DatabasesJournal of the Operational Research Society
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A Generic Method of Line Matching for Central Imaging Systems under Short-Baseline Motion

2009

Line matching across images taken by a central imaging system (perspective or catadioptric) with focus on short baseline motion of the system is proposed. The relationship between images of lines on unitary sphere is studied and a simple algorithm for matching lines are proposed assuming the rotation of the system is known apriori or it can be estimated from some correspondences in two views. Two methods are discussed for retrieving R in the case it is not known apriori. Experimental results on both synthetic and real images are also presented.

Matching (statistics)Computer sciencebusiness.industryEpipolar geometryReal imageGreat circleCatadioptric systemPerspective (geometry)Computer visionArtificial intelligencebusinessFocus (optics)Rotation (mathematics)Computer Science::Databases
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The ultrafast dynamics and conductivity of photoexcited graphene at different Fermi energies

2017

The ultrafast dynamics and conductivity of photoexcited graphene can be explained using solely electronic effects.

Materials SciencePhysics::OpticsFOS: Physical sciences02 engineering and technology01 natural sciences7. Clean energylaw.inventionCondensed Matter::Materials ScienceElectrical resistivity and conductivitylawMesoscale and Nanoscale Physics (cond-mat.mes-hall)0103 physical sciencesPhysics::Atomic and Molecular ClustersPhysics::Chemical Physics010306 general physicsComputer Science::DatabasesResearch ArticlesPhysicsMultidisciplinaryCondensed Matter - Mesoscale and Nanoscale PhysicsCondensed matter physicsScatteringGraphenePhotoconductivitygraphene ultrafast carrier dynamicSciAdv r-articlesFermi energyPhysik (inkl. Astronomie)Condensed Matter Physics021001 nanoscience & nanotechnologyBoltzmann equation3. Good healthPhotoexcitationMultiple exciton generation0210 nano-technologyResearch ArticleScience Advances
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Near-infrared radiative transfer modelling with different CH4 spectroscopic databases to retrieve atmospheric methane total amount

2011

International audience; Atmospheric methane content can be retrieved from measurements of solar radiation attenuated by the atmosphere in the near infrared spectral region where the space-borne and ground-based spectrometers carry out regular measurements. It is shown, in the present work, that the different spectroscopic databases can give significantly different results for both forward simulations of the atmospheric transmittance and the inverse problem solution to retrieve the CH4 total content in the atmosphere using spectra measured by ground-based FTIR spectrometer in the near infrared spectral region. These discrepancies and the problem of the reduction of their influence on the atm…

Materials science010504 meteorology & atmospheric sciencesInfrared spectroscopycomputer.software_genre01 natural sciencesAtmosphereAtmospheric radiative transfer codes0103 physical sciencesRadiative transferAstrophysics::Solar and Stellar AstrophysicsPhysics::Atmospheric and Oceanic PhysicsSpectroscopySpectroscopic databases0105 earth and related environmental sciencesRadiation010304 chemical physicsSpectrometerDatabaseAtmospheric methaneNear-infrared spectroscopyAtmospheric transmissionAtomic and Molecular Physics and Optics13. Climate actionInfrared windowAstrophysics::Earth and Planetary AstrophysicsMethanecomputerJournal of Quantitative Spectroscopy and Radiative Transfer
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