Search results for "Databases"

showing 10 items of 937 documents

Common Factors in Neurodegeneration: A Meta-Study Revealing Shared Patterns on a Multi-Omics Scale

2020

Neurodegenerative diseases such as Alzheimer&rsquo

Proteomicsamyotrophic lateral sclerosisParkinson's diseaseDatabases FactualProteomeDiseaseComputational biologyBiologyPolymorphism Single NucleotideArticleTranscriptomeImmune systemHuntington's diseaseAlzheimer DiseasemedicineHumansbiochemistryAmyotrophic lateral sclerosislcsh:QH301-705.5GeneAlzheimer’s disease ; multi-omics ; neurodegeneration ; Huntington’s disease ; Parkinson’s disease ; amyotrophic lateral sclerosisNeurodegenerationneurodegenerationNeurodegenerative DiseasesParkinson DiseaseGenomicsGeneral Medicinemulti-omicsmedicine.diseaseImmunity HumoralGene OntologyHuntington Diseaselcsh:Biology (General)Parkinson’s diseaseTranscriptomeAlzheimer’s diseaseGenome-Wide Association StudyHuntington’s disease
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Surface analysis of Dicrocoelium dendriticum. The molecular characterization of exosomes reveals the presence of miRNAs

2013

Abstract With the aim of characterizing the molecules involved in the interaction of Dicrocoelium dendriticum adults and the host, we have performed proteomic analyses of the external surface of the parasite using the currently available datasets including the transcriptome of the related species Echinostoma caproni. We have identified 182 parasite proteins on the outermost surface of D. dendriticum. The presence of exosome-like vesicles in the ESP of D. dendriticum and their components has also been characterized. Using proteomic approaches, we have characterized 84 proteins in these vesicles. Interestingly, we have detected miRNA in D. dendriticum exosomes, thus representing the first rep…

ProteomicsbiologyDicrocoelium dendriticumBiophysicsHelminth ProteinsComputational biologyExosomesbiology.organism_classificationProteomicsBiochemistryExosomeMicrovesiclesTranscriptomeMicroRNAsmicroRNAImmunologyAnimalsParasite hostingHelminthsDicrocoeliumRNA HelminthDatabases ProteinJournal of Proteomics
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Automated anaesthesia record systems, observations on future trends of development.

1995

The introduction of electronic anaesthesia documentation systems was attempted as early as in 1979, although their efficient application has become reality only in the past few years. Today, documentation technology is offered by most of the monitor manufacturers and new systems are being developed by various working groups. The advantages of the electronic protocol are apparent: Continuous high quality documentation, comparability of data due to the availability of a anaesthesia data bank, reduction of the workload of the anaesthesia staff and availability of new additional information. Disadvantages of the electronic protocol have also been discussed. Typically, by going through the proce…

Protocol (science)Quality ControlDatabases FactualComputer scienceProcess (engineering)media_common.quotation_subjectMedicine (miscellaneous)WorkloadCritical Care and Intensive Care MedicineMedical RecordsUser-Computer InterfaceDocumentationData loggerInformation systemQuality (business)Operations managementAnesthesiaUser interfaceSimulationmedia_commonForecastingInternational journal of clinical monitoring and computing
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Scientific Publications and Research Groups on Alcohol Consumption and Related Problems Worldwide: Authorship Analysis of Papers Indexed in PubMed an…

2011

BACKGROUND: The research of alcohol consumption-related problems is a multidisciplinary field. The aim of this study is to analyze the worldwide scientific production in the area of alcohol-drinking and alcohol-related problems from 2005 to 2009. METHODS: A MEDLINE and Scopus search on alcohol (alcohol-drinking and alcohol-related problems) published from 2005 to 2009 was carried out. Using bibliometric indicators, the distribution of the publications was determined within the journals that publish said articles, specialty of the journal (broad subject terms), article type, language of the publication, and country where the journal is published. Also, authorship characteristics were assesse…

PubMedBiomedical ResearchAlcohol DrinkingDatabases FactualAbstracting and IndexingMEDLINEeducationSpecialtyScopusMEDLINEMedicine (miscellaneous)Poison controlBibliometricsGlobal HealthToxicologycomputer.software_genreInjury preventionHumansMedicineDatabasebusiness.industrySubject (documents)AuthorshipPsychiatry and Mental healthIndex (publishing)Periodicals as TopicbusinesscomputerAlcoholism: Clinical and Experimental Research
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Advice for health-care professionals on how to retrieve more efficiently scientifically strong and up-to-date studies on treatments by PubMed.

2008

AND trial (Title/Abstract))). Obviously, clini- cians using the PubMed Clinical Queries may be unaware of the PubMed search engine technical approach even whether they can remain unaware of what the PubMed search engine is doing. We demonstrated substantial mild retrieval bias of PubMed Clinical Queries filter focusing on therapy (narrow search) that can miss up-to-date scientifically information on treatments. This bias occurs because the search string does not consider the Britannic English variant of the term randomized (i.e., randomised). We suggested a slight change in the original search string by the addition of the term randomised as follows: (randomized controlled trial (Publicatio…

PubMedEvidence-Based Medicinebusiness.industryHealth PersonnelAccess to Information MEDLINEInformation Storage and RetrievalSlight changemedicine.diseaseDatabases BibliographicAdvice (programming)law.inventionAccess to InformationRandomized controlled trialHealth OccupationslawHealth careEmergency MedicineInternal MedicineHumansMedicineMedical emergencybusiness
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Comparison between two five year periods (1998/2002 and 2003/2007) on the production, impact and co-authorship of publications on tobacco and smoking…

2010

Abstract Objective The aim of this study was to compare the production, impact and co-authorship of publications by Spanish authors on smoking and tobacco between two time periods (1998/2002 vs. 2003/2007) using Science Citation Index (SCI). Methods The literature search was performed in the SCI-Expanded on 20 November 2008. All types of documents by Spanish authors were selected. The search was restricted to the title, and the key words used were “smok*” and “tobac*”. The statistical analysis was descriptive (95% CI). Results A total of 588 documents were retrieved, with 399 (67.85%) original papers, 54 (9.18%) letters to the editor and 35 (5.95%) editorials. Productivity increased from th…

PublishingIndex (economics)Time Factorsbiologybusiness.industryScientific productionSmokingScience Citation IndexGeneral Medicinebiology.organism_classificationDatabases BibliographicAuthorshipSmokSpainTobaccoMedicineCo authorshipStatistical analysisJournal Impact FactorbusinessDemographyArchivos de bronconeumologia
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[Evolution and scientific impact of research grants from the spanish society of cardiology and spanish heart foundation (2000-2006)].

2011

Abstract Introduction and objectives The Sociedad Espanola de Cardiologia (Spanish Society of Cardiology) every year awards grants to finance research in the field of cardiovascular diseases. The aim of this study is to identify the impact of these investments during the period 2000-2006 from the subsequently published articles in scientific journals. Methods Using the identifying data of each project as search terms, all articles that resulted from these grants were located in the Spanish Indice Medico Espanol and Indice Bibliografico Espanol en Ciencias de la Salud databases, and in Science Citation Index-Expanded and Scopus. Descriptive statistical analysis of these articles included typ…

Publishingmedicine.medical_specialtyImpact factorDatabases Factualbusiness.industryScopusCardiologyFoundation (evidence)General MedicineSearch termsInstitutional affiliationSpainInternal medicineResearch Support as TopicCardiologyMedicineStatistical analysisJournal Impact FactorPeriodicals as TopicbusinessCitationFoundationsRevista espanola de cardiologia
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Nocturnal intermittent hypoxia predicts prevalent hypertension in the European Sleep Apnoea Database cohort study.

2014

Systemic hypertension is associated with obstructive sleep apnoea syndrome (OSAS) but the pathophysiological mechanisms are incompletely understood. A collaborative European network of 24 sleep centres established a European Sleep Apnoea Database to evaluate cardiovascular morbidity associated with OSAS.11 911 adults referred with suspected OSAS between March 2007 and September 2013 underwent overnight sleep studies, either cardiorespiratory polygraphy or polysomnography. We compared the predictive value of the apnoea–hypopnoea index (AHI) and 4% oxygen desaturation index (ODI) for prevalent hypertension, adjusting for relevant covariates including age, smoking, obesity, dyslipidaemia and d…

Pulmonary and Respiratory MedicineAdultMaleAdolescentDatabases FactualCross-sectional studyPolysomnographyPolysomnographySettore MED/10 - Malattie Dell'Apparato Respiratoriocomputer.software_genreta3111Sleep apnoea hypoxia hypertensionCohort StudiesYoung Adultstomatognathic systemmedicinePrevalenceHumansapnea hypopnea index oxygen desaturation index blood pressureHypoxiaAgedAged 80 and overSleep Apnea ObstructiveDatabasemedicine.diagnostic_testbusiness.industrySleep apneaIntermittent hypoxiaCardiorespiratory fitnessOdds ratioMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREMiddle Agedmedicine.diseaseObesitynervous system diseasesrespiratory tract diseasesEuropeCross-Sectional StudiesHypertensionFemalebusinesscomputerCohort studyThe European respiratory journal
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THE EUROPEAN SLEEP APNOEA DATABASE (ESADA) -- Report from 22 European Sleep Laboratories

2011

The European Sleep Apnoea Database (ESADA) reflects a network of 22 sleep disorder centres in Europe enabled by a COST action B26 programme. This ongoing project aims to describe differences in standard clinical care of patients with obstructive sleep apnoea (OSA) and to establish a resource for genetic research in this disorder. Patients with suspected OSA are consecutively included and followed up according to local clinical standards. Anthropometrics, medical history, medication, daytime symptoms and sleep data (polysomnography or cardiorespiratory polygraphy) are recorded in a structured web-based report form. 5,103 patients (1,426 females, mean±SD age 51.8±12.6 yrs, 79.4% with apnoea/h…

Pulmonary and Respiratory MedicineAdultMalePediatricsmedicine.medical_specialtyAdolescentDatabases FactualCross-sectional studyPolysomnographyComorbidityCohort StudiesSleep Apnea SyndromesRisk FactorsSurveys and QuestionnairesmedicineHumansMedical historyRespiratory systemAgedSleep disordermedicine.diagnostic_testAnthropometryModels Geneticbusiness.industrycomorbidity European Sleep Apnoea Database genetic multicentre cohort obstructive sleep apnoea syndromeCardiorespiratory fitnessMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREAnthropometryMiddle Agedmedicine.diseaserespiratory tract diseasesObesity MorbidEuropeCohortFemaleHuman medicinebusiness
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Chronic rhinosinusitis with nasal polyps impact in severe asthma patients: Evidences from the Severe Asthma Network Italy (SANI) registry

2020

Abstract Background The clinical and laboratory features of patients enrolled in the Severe Asthma Network in Italy (SANI) registry, a web-based observatory collecting demographic, clinical, functional and inflammatory data of patients with severe asthma were evaluated, with a special emphasis to chronic rhinosinusitis with nasal polyposis (CRSwNP). Methods For each eligible patients the following information has been collected: demographic data, clinical features, asthma control in the previous month according to the GINA (Global INitiative for Asthma) Guidelines and standardized questionnaires, concomitant regular and on demand treatments and inflammatory markers. Results 695 patients wit…

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialtySevere asthmaDatabases FactualAdministration OralComorbiditySettore MED/10 - Malattie Dell'Apparato RespiratorioNitric OxideSeverity of Illness IndexComorbiditiesOral corticosteroidAdrenal Cortex HormonesInternal medicineSeverity of illnessOral corticosteroidsmedicinePrevalenceNasal polypsHumansNasal polypsRegistriesSinusitisSinusitisAsthmaAgedRhinitisInternetBronchiectasisbusiness.industryNasal polypSettore MED/09 - MEDICINA INTERNAAtopic dermatitisComorbidities; Nasal polyps; Oral corticosteroids; Severe asthmaMiddle Agedmedicine.diseaseComorbidityAsthmaComorbidities Nasal polyps Oral corticosteroids Severe asthmaItalyConcomitantChronic DiseaseDisease ProgressionFemaleComorbiditiebusiness
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