Search results for "Delay"

Association between passive tobacco exposure and caries in children and adolescents. A systematic review and meta-analysis.

2017

To examine the available evidence on the association between exposure to tobacco use in the womb and in infancy and the presence of caries in primary and permanent dentition in children and adolescents. A systematic review was conducted through searches in 4 data bases (Pubmed, Scopus, Embase and Web of Science), complemented by hand-searching. Of the 559 articles identified, 400 were duplicates. Finally, 28 articles were included in the qualitative review and 21 in the meta-analysis. Their quality was assessed using the Newcastle-Ottawa scale. The quality was medium in 44% of the articles included and high in 56%. The overall meta-analysis gave a significant odds ratio (OR = 1.53, 95% conf…

MR3098564 Reviewed Al-Thagafi, M. A.; Shahzad, Naseer Krasnosel'skii-type fixed-point results. J. Nonlinear Convex Anal. 14 (2013), no. 3, 483–491. (…

2014

The Krasnosel'skii fixed-point theorem is a powerful tool in dealing with various types of integro-differential equations. The initial motivation of this theorem is the fact that the inversion of a perturbed differential operator may yield the sum of a continuous compact mapping and a contraction mapping. Following and improving this idea, many fixed-point results were proved.\\ The authors present significant and interesting contributions in this direction. In particular, they give the following main theorem: \begin{theorem} Let $M$ be a nonempty bounded closed convex subset of a Banach space $E$, $S:M \to E$ and $T:M \to E$. Suppose that \begin{itemize} \item[(a)] $S$ is 1-set-contractive…

Efficiency optimization in bi-directional inductive power transfer systems

2015

Inductive Power Transfer (IPT) allows to wirelessly supply electronic devices. Thus, it is a very smart technique of battery charging for electric vehicles. In a parking area scenario, IPT is a proper method aiming at the energy transfer from the vehicle battery to the electric grid too. Bi-Directional Inductive Power Transfer (BDIPT) Systems are an attractive solution for the automotive market. Due to the great relevance of the energy saving problem, the goal of an efficiency maximization is researched by the energy market. In this paper, an in-depth investigation of the power efficiency in BDIPT systems is carried out, aiming at the optimum efficiency.

Antimicrobial beeswax coated polylactide films with silver control release capacity.

2013

Although the application of silver based antimicrobial systems is a widespread technology, its implementation in areas such as food packaging is still challenging. The present paper describes the fabrication of poly(lactic acid) (PLA) coated with beeswax with controlled release properties for sustained antimicrobial performance. Release of silver ions from the polymers was monitored voltammetrically under various conditions (surface contact, immersion in various liquid media and at different pH values) throughout at least 7days. A higher release was noted with decreasing pH while surface release was much slower than the release when immersed in liquid medium. While uncoated films demonstrat…

Recent advances on thermosensitive and pH-sensitive liposomes employed in controlled release

2019

Nanotechnology has recently gained lots of interest in drug delivery due to its potential to improve the therapeutic outcomes of various diseases. Particularly, a wide range of different nano-sized vesicles has been investigated for drug delivery. Among them, one of the most attractive and well-investigated nanocarriers are liposomes. Although liposomes have several advantages such as low toxicity, biodegradability and biocompatibility as well as accumulate in tumor site via enhanced permeability and retention (EPR) effect, inefficient drug delivery to the target cells could affect the therapeutic purpose of most of conventional liposomal formulations. Therefore, new systems of drug release…

Prenatal cocaine exposure alters spontaneous and cocaine-induced motor and social behaviors.

2005

The abuse of cocaine in pregnant women could affect emotional behaviors in their descendents. The aim of this work was to evaluate the effects of prenatal cocaine exposure on spontaneous and cocaine-induced motor and social behaviors in mice. Three kinds of prenatal treatment were used: non-treated animals; mice treated daily with physiological saline during the last week of pregnancy; and finally, those treated with cocaine (25 mg/kg) during the same period. Behavioral studies took place on adult males, which were housed in two different conditions: grouped (non-aggressive), or isolated (aggressive). Cocaine-pretreated animals exhibited slight differences in spontaneous motor activity, but…

Long-term effects on offspring of early exposure to biological and external factors

2000

Encapsulation of polyprodrugs enables an efficient and controlled release of dexamethasone

2021

Water-soluble low molecular weight drugs, such as the synthetic glucocorticoid dexamethasone (DXM), can easily leak out of nanocarriers after encapsulation due to their hydrophilic nature and small size. This can lead to a reduced therapeutic efficacy and therefore to unwanted adverse effects on healthy tissue. Targeting DXM to inflammatory cells of the liver like Kupffer cells or macrophages is a promising approach to minimize typical side effects. Therefore, a controlled transport to the cells of interest and selective on-site release is crucial. Aim of this study was the development of a DXM-phosphate-based polyprodrug and the encapsulation in silica nanocontainers (SiO2 NCs) for the red…

Duration of untreated psychosis in first-episode psychosis is not associated with common genetic variants for major psychiatric conditions: results f…

2021

The EU-GEI Project is funded by the European Community’s Seventh Framework Programme under grant agreement No. HEALTH-F2-2010–241909 (Project EU-GEI).

The effects of alpha-cypermethrin exposure on biochemical and redox parameters in pregnant rats and their newborns

2016

IF 2.388; International audience; Pyrethroid insecticides are extensively used in agriculture and in household activities. During pregnancy, they might affect maternal metabolic status and there after fetal development. In this work, we studied metabolic and redox effects of low dose alpha-cypermethrin exposure in pregnant rats and their offspring. The diet containing alpha cypermethrin at 0.02 mg/kg/day was consumed during the entire gestation. Plasma biochemical parameters as well as liver lipid and oxidative stress markers were determined. Our results showed that alpha-cypermethrin induced an increase in body weight and in plasma glucose and lipid levels, as well as in plasma aspartate a…