Search results for "Density"

showing 10 items of 4402 documents

Iron(III) bis(pyrazol-1-yl)acetate based decanuclear metallacycles: synthesis, structure, magnetic properties and DFT calculations

2016

The synthesis, structural aspects, magnetic interpretation and theoretical rationalizations for a new member of the ferric wheel family, a decanuclear iron(III) complex with the formula [Fe10(bdtbpza)10(μ2-OCH3)20] (1), featuring the N,N,O tridentate bis(3,5-di-tert-butylpyrazol-1-yl)acetate ligand, are reported. The influence of the steric effect on both the core geometry and coordination mode is observed. Temperature dependent (2.0–300 K range) magnetic susceptibility studies carried out on complexes 1 established unequivocally antiferromagnetic (AF) interactions between high-spin iron(III) centers (S = 5/2), leading to a ground state S = 0. The mechanism of AF intramolecular coupling was…

Steric effects010405 organic chemistryChemistryStereochemistryLigand010402 general chemistry01 natural sciencesMagnetic susceptibility0104 chemical sciencesInorganic ChemistryCrystallographyiron complexesIntramolecular forcemetallacyclesmedicineFerricAntiferromagnetismacetate ligandsmagnetic propertiesGround stateta116density functional theoryMagnetic interpretationmedicine.drugDalton Transactions
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Understanding the molecular mechanism of the [3 + 2] cycloaddition reaction of benzonitrile oxide toward electron-richN-vinylpyrrole: a DFT study

2016

The [3 + 2] cycloaddition (32CA) reaction of benzonitrile oxide, BNO 2, with an electron-rich N-vinylpyrrole derivative, NVP 3a, in the presence of dichloromethane, has been theoretically studied using density functional theory (DFT) methods at the B3LYP/6-31G(d) level. This 32CA reaction presents a relatively high activation Gibbs free energy as a result of the low polar character of this zwitterionic-type (zw-type) reaction. Analyses of the calculated relative Gibbs free energies and transition state geometries indicate that the studied 32CA reaction, in excellent agreement with experimental outcomes, takes place in a complete regioselective manner as a consequence of the steric repulsion…

Steric effects010405 organic chemistryOrganic Chemistry010402 general chemistry01 natural sciencesCycloadditionElectron localization function0104 chemical sciencesGibbs free energysymbols.namesakechemistry.chemical_compoundBenzonitrilechemistryComputational chemistrysymbolsSingle bondDensity functional theoryPhysical and Theoretical ChemistryDerivative (chemistry)Journal of Physical Organic Chemistry
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Stability of Dinuclear Phosphane Palladium(III) Complexes: A DFT Approach

2018

Computational density functional theory studies have been carried out for the dinuclear ortho-metalated palladium(III) compounds [Pd2{μ-(C6H4)PPh2}2{μ-(X1-X2)}2Cl2]. These studies have shown that the electronic and steric properties of the auxiliary ligands (X1-X2 = bridging (carboxylato) or chelating (phenolato/acetylacetonato) O,O-donor ligands, bridging N,N-donor ligands (triazenido/formamidinato/pyrazolato), and bridging N,S-donor ligands) lead to systematic trends in their stability, highlighting that (a) the electronic nature of the donor atoms trans to the P has a clear trend, the replacement of hard donor atoms (O, N) by softer S donors generally reducing the stability of the compou…

Steric effects010405 organic chemistryOrganic Chemistrychemistry.chemical_element010402 general chemistry01 natural sciences0104 chemical sciencesInorganic ChemistryCrystallographychemistryIntramolecular forceDensity functional theoryChelationPhysical and Theoretical ChemistryPalladiumOrganometallics
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A Density Functional Study of Open-Shell Cyclopentadienyl−Molybdenum(II) Complexes. A Comparison of Stabilizing Factors: Spin-Pairing, Mo−X π Bonding…

2000

International audience; The dissociation of PH3 from the 18-electron system CpMoX(PH3)3 to afford the corresponding 16-electron CpMoX(PH3)2 fragment has been investigated theoretically by density functional theory for X = H, CH3, F, Cl, Br, I, OH, and PH2. The product is found to prefer a triplet spin state for all X ligands except PH2, the singlet−triplet gap varying between 1.7 kcal/mol for OH to 8.7 kcal/mol for F. The Mo−PH3 bond dissociation energy to the 16-electron ground state varies dramatically across the series, from 4.5 kcal/mol for OH to 23.5 kcal/mol for H, and correlates with experimental observations on trisubstituted phosphine derivatives. Geometry-optimized spin doublet Cp…

Steric effects010405 organic chemistrychemistry.chemical_element010402 general chemistryLigands01 natural sciencesQuantum mechanicsDissociation (chemistry)Bond cleavageStabilization0104 chemical sciencesInorganic ChemistryCrystallographychemistryCyclopentadienyl complexMathematical methodsComputational chemistryMolybdenumPairingDensity functional theory[CHIM.COOR]Chemical Sciences/Coordination chemistryPhysical and Theoretical ChemistryOpen shellBond cleavage
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Synthesis and stereochemical properties of "extended" biphenols bridged by ortho-, meta-, and para-phenylene spacers

2009

A series of isomeric biphenols based on para- (1), meta- (2), and ortho- (3) terphenyl backbones was synthesized. Suzuki cross-coupling methodology was employed for the construction of the terphenyl backbone of their methyl-protected precursors (respectively 8, 13, and 16). Using K2CO3 as the base, the best reaction conditions involved DMF at 100 °C as solvent. Anhydrous conditions greatly improved the yields of the sterically crowded systems (particularly 16). ortho-Terphenyls 3 and 16 exist as mixtures of syn/anti atropisomers in solution. Compound 16 crystallizes in the anti-in form. DFT calculations at the B3LYP/6-311+G(d,p) level indicate that for both compounds the anti-in form is mor…

Steric effectsAtropisomer010405 organic chemistryChemistryStereochemistryOrganic ChemistryContext (language use)010402 general chemistry01 natural sciencesMedicinal chemistryChemical synthesisAtropisomerism0104 chemical sciences[SHS]Humanities and Social SciencesSolventchemistry.chemical_compoundDensity functional calculationsSuzuki reactionPhenyleneTerphenyl[ SHS ] Humanities and Social SciencesCross-couplingBiarylsPhysical and Theoretical ChemistryComputingMilieux_MISCELLANEOUS
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Dinitrogen complexation with main group radicals

2011

In this report we present data from hyperfine sublevel correlation spectroscopy (HYSCORE), an electron paramagnetic resonance (EPR) spectroscopic technique, that reveals weak but distinct interactions between several main group element radicals and physically dissolved dinitrogen in solution. These interactions are the basis for a well-defined coordination of N2 to the paramagnetic centers. The complexes formed are primarily of the van der Waals-type but also feature a non-negligible orbital overlap between dinitrogen and the radicals' SOMO. Our spectroscopic findings are strongly supported by experiments with isotope-labeled 15N2, spectral simulations and quantum chemical and density funct…

Steric effectsChemistryGeneral ChemistryOrbital overlapPhotochemistrylaw.inventionsymbols.namesakeMain group elementComputational chemistryPolarizabilitylawsymbolsDensity functional theoryPhysics::Chemical Physicsvan der Waals forceElectron paramagnetic resonanceHyperfine structureChem. Sci.
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Unveiling the Ionic Diels-Alder Reactions within the Molecular Electron Density Theory

2021

The ionic Diels–Alder (I-DA) reactions of a series of six iminium cations with cyclopentadiene have been studied within the Molecular Electron Density Theory (MEDT). The superelectrophilic character of iminium cations, ω &gt

Steric effectsCyclopentadienePharmaceutical ScienceIonic bonding010402 general chemistry01 natural sciencesArticleAnalytical Chemistrychemistry.chemical_compoundQD241-441Computational chemistryDrug Discoveryionic Diels–Alder reactionsReactivity (chemistry)Physical and Theoretical Chemistryorganic_chemistry010405 organic chemistryChemistryOrganic ChemistrySolvationCationic polymerizationMolecular Electron Density TheoryIminiumiminium cationsElectron localization function3. Good health0104 chemical sciencesChemistry (miscellaneous)asynchronicityglobal electron density transfersuperelectrophilesMolecular Medicine
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Unveiling the regioselectivity in electrophilic aromatic substitution reactions of deactivated benzenes through molecular electron density theory

2021

The origin of the meta regioselectivity in electrophilic aromatic substitution (EAS) reactions of deactivated benzene derivatives is herein analysed through Molecular Electron Density Theory (MEDT). To this end, the EAS reaction of benzenesulfonic acid with the nitronium NO2+ ion in H2SO4 solution has been studied at the ωB97X-D/6-311G(d,p) level. This reaction takes place through a two-step polar mechanism involving the formation of an unstable cation intermediate. The activation Gibbs free energies associated with the three competitive regioisomeric reaction paths are found in the narrow range of 15.5–18.3 kcal mol−1. By using the Eyring–Polanyi equation a relationship of 18.7 (ortho) : 8…

Steric effectsElectron density010405 organic chemistryRegioselectivityGeneral ChemistryElectrophilic aromatic substitution010402 general chemistryRing (chemistry)01 natural sciencesMedicinal chemistryCatalysis0104 chemical sciencesGibbs free energychemistry.chemical_compoundsymbols.namesakeBenzenesulfonic acidchemistryMaterials ChemistrysymbolsBenzeneNew Journal of Chemistry
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Steric interactions controlling the syn diastereofacial selectivity in the [3 + 2] cycloaddition reaction between acetonitrile oxide and 7-oxanorborn…

2017

A Molecular Electron Density Theory study of the zw-type 32CA reactions of acetonitrile oxide (NO) with two 7-oxanorborn-5-en-2-ones (ONBs) has been performed at the DFT B3LYP/6-31G(d) computational level. These cycloadditions proceed through one-step mechanisms with high activation energies and present low para regio and complete syn diastereofacial selectivities. While the non-polar character of these zw-type 32CA reactions, which is the consequence of the insufficient electrophilic activation of ONBs, according to the analysis of the conceptual DFT reactivity indices, accounts for the high activation energies, and low para regioselectivity, NCI topological analyses at the anti/syn pairs …

Steric effectsElectron density010405 organic chemistryStereochemistryChemistryOrganic ChemistryRegioselectivity010402 general chemistry01 natural sciencesCycloaddition0104 chemical sciencesAcetonitrile oxideComputational chemistryElectrophileReactivity (chemistry)Physical and Theoretical ChemistrySelectivityJournal of Physical Organic Chemistry
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Valence Topological Charge-Transfer Indices for Reflecting Polarity: Correction for Heteromolecules

2005

Valence topological charge-transfer (CT) indices are applied to the calculation of dipole moments mu. The mu calculated by algebraic and vector semisums of the CT indices are defined. The model is generalized for molecules with heteroatoms and corrected for sp(3)-heteromolecules. The ability of the indices for the description of the molecular charge distribution is established by comparing them with mu of the valence-isoelectronic series of cyclopentadiene, benzene and styrene. Two CT indices, mu(vec) (vector semisum of vertex-pair mu) and mu(vec)V (valence mu(vec)) are proposed. The mu(vec) behaviour is intermediate between mu(vec) and mu(experiment). The correction is produced in the corr…

Steric effectsHeteroatomBiophysicsPharmaceutical ScienceElectronsFluorescence PolarizationMolecular physicsArticleBiophysical PhenomenaAnalytical ChemistryValence topological charge-transfer indexElectronegativitylcsh:QD241-441Atomic orbitallcsh:Organic chemistryHeterocyclic CompoundsReference ValuesComputational chemistryDrug DiscoveryCharge distributionPhysical and Theoretical ChemistryTopological quantum numberDipole momentValence (chemistry)ChemistryOrganic ChemistryCharge densityBenzeneModels TheoreticalDipoleChemistry (miscellaneous)HeteroatomMolecular MedicineIsolelectroic seriesMolecules
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