Search results for "Density"

showing 10 items of 4402 documents

Osteonecrosis of the jaw related to non-antiresorptive medications: a systematic review

2018

The reporting of osteonecrosis of the jaw (ONJ) related to anticancer agents without known antiresorptive properties (non-antiresorptives), such as antiangiogenics, tyrosine kinase inhibitors, mammalian target of rapamycin inhibitors, immune checkpoint inhibitors, and cytotoxic chemotherapy is increasing. To review characteristics of ONJ in cancer patients receiving non-antiresorptives. A systematic review of the literature between 2009 and 2017 was conducted by the Bone Study Group of MASCC/ISOO. Of 6249 articles reviewed and from personal communication, 42 ONJ cases related to non-antiresorptives were identified. No gender predilection was noted. Median age was 60 years and ONJ stage 2 wa…

AdultMaleOncologyBRAF inhibitormedicine.medical_specialtymTOR inhibitorsImmune checkpoint inhibitorsInhibitors of angiogenesiTyrosine kinase inhibitorBone resorptionImmune checkpoint inhibitorDelayed diagnosisCytotoxic chemotherapyBone resorption03 medical and health sciences0302 clinical medicineProstateInternal medicinemedicineHumans030212 general & internal medicineStage (cooking)AgedBone Density Conservation AgentsDiphosphonatesOsteonecrosis of the jawbusiness.industryOsteonecrosisCancerMiddle AgedCytotoxic chemotherapymedicine.diseasemedicine.anatomical_structureJawOncology030220 oncology & carcinogenesisBisphosphonate-Associated Osteonecrosis of the JawFemaleOsteonecrosis of the jawbusiness
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Correlates of increased lean muscle mass in women with polycystic ovary syndrome.

2009

ObjectiveMuscle mass plays an important role in determining cardiovascular and metabolic risks in polycystic ovary syndrome (PCOS). In addition, whether lean mass influences carotid intima-media thickness (IMT) in PCOS has not been assessed.DesignProspective investigation.MethodsNinety-five women with PCOS were age- and weight-matched to 90 ovulatory controls. All women had dual X-ray absorptiometry for lean, fat and bone mass, and bone mass density (BMD). Serum testosterone, sex hormone-binding globulin, insulin, and glucose and carotid IMT were determined. Free androgen index (FAI) and insulin resistance (by QUICKI) were calculated.ResultsIn PCOS, waist circumference and insulin were high…

AdultMaleOvulationmedicine.medical_specialtySettore MED/09 - Medicina InternaBone densityAdolescentEndocrinology Diabetes and Metabolismmedicine.medical_treatmentBiologySettore MED/13 - EndocrinologiaBody Mass IndexYoung AdultEndocrinologyWaist–hip ratioInsulin resistanceAbsorptiometry PhotonInternal medicinemedicineHumansInsulinTestosteroneMuscle SkeletalUltrasonographyPCOS Muscle mass Cardiovascular risk atherosclerosis endotheliumFree androgen indexWaist-Hip RatioInsulinBody Weightnutritional and metabolic diseasesGeneral Medicinemedicine.diseaseSettore MED/11 - Malattie Dell'Apparato CardiovascolarePolycystic ovaryEndocrinologyCarotid ArteriesLean body massAndrogensBody CompositionFemaleSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' MotorieBody mass indexPolycystic Ovary SyndromeEuropean journal of endocrinology
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The effect of olive oil polyphenols on antibodies against oxidized LDL. A randomized clinical trial

2010

summary Background & aim: Oxidized LDL (oxLDL) is a highly immunogenic particle that plays a key role in the development of atherosclerosis. Some data suggest a protective role of OxLDL autoantibodies (OLAB) in atherosclerosis. Our aim was to assess the effect of olive oil polyphenols on the immunogenicity of oxLDL to autoantibody generation. Methods: In a crossover, controlled trial, 200 healthy men were randomly assigned to 3-week sequences of 25 mL/day of 3 olive oils with high (366 mg/kg), medium (164 mg/kg), and low (2.7 mg/kg) phenolic content. Results: Plasma OLAB concentration was inversely associated with oxLDL (p < 0.001). Olive oil phenolic content increased OLAB generation, with…

AdultMaleOxidized low density lipoproteinCritical Care and Intensive Care MedicineOxidative damageYoung AdultTandem Mass SpectrometryHumansPlant OilsMedicineFood scienceOlive OilChromatography High Pressure LiquidAutoantibodiesCross-Over StudiesNutrition and Dieteticsbiologybusiness.industryAutoantibodyPolyphenolsMiddle AgedLipoproteins LDLOxidative StressBiochemistryPolyphenolLinear Modelsbiology.proteinlipids (amino acids peptides and proteins)Lipid PeroxidationAntibodybusinessOxidized ldlOlive oilClinical Nutrition
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Development of a novel histological and histomorphometric evaluation protocol for a standardized description of the mid‐palatal suture – An ex vivo s…

2019

The hard palate and mid‐palatal suture are highly important for orthodontic treatment. In cases of transverse maxillary deficiency, palatal expansion is the treatment of choice. As nowadays a growing number of adult patients receive orthodontic treatment, an understanding of suture development throughout life is important to derive tailored orthodontic treatment techniques for each age group. Histological, histochemical and immunohistochemical stains (haematoxylin & eosin, Azan, Movat pentachrome, Masson–Goldner trichrome, Sirius Red, CD 31, osteopontin and TRAP) and histomorphometric analyses were re‐established to detect the structural conditions of the mid‐palatal suture in human cadaver…

AdultMalePalate Hard0301 basic medicineHistologyBone densityHaematoxylinYoung Adult03 medical and health scienceschemistry.chemical_compound0302 clinical medicineSuture (anatomy)TrichromeMaxillaMethodsmedicineHumansMolecular BiologySirius RedEcology Evolution Behavior and SystematicsAgedOrthodonticsbusiness.industryHistological TechniquesHistologyCranial SuturesCell BiologyMiddle AgedStaining030104 developmental biologymedicine.anatomical_structurechemistryFemaleHard palateAnatomybusiness030217 neurology & neurosurgeryDevelopmental BiologyJournal of Anatomy
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Anatomic site evaluation of the palatal bone for temporary orthodontic anchorage devices.

2008

: Objectives: The aim of the present study was to assess the micromorphologic characteristics of the palatal bone from an implantologic standpoint. Materials and Methods: The material consisted of tissue blocks of autopsy material from 22 subjects (18 males, three females) between 18 and 63 years of age. The specimens comprised the anterior median palatal region from 5 to 10 mm behind the incisive foramen. They were prepared in the transversal plane according to ground thin-section technology. The midpalatal area as well as an area of 3 mm bilateral to the midline were assessed, and a classification of quantitative palatal bone availability was developed. Results: The findings could be divi…

AdultMalePalate HardBone densityAdolescentDentistryAnatomic SiteSuture (anatomy)Orthodontic AppliancesCadaverBone DensityCadaverOrthodontic Anchorage ProceduresMedicineHumansIncisive foramenAgedOrthodonticsbusiness.industryDental Implantation EndosseousMiddle AgedClassificationTrabecular bonemedicine.anatomical_structureCompact boneCortical boneFemaleOral SurgerybusinessClinical oral implants research
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Bone quality in the midpalate for temporary anchorage devices.

2009

Objective The aim of the present study was to quantitatively assess the bone quality of the palatal bone from an implantologic standpoint. Material and methods The material consisted of palatal tissue blocks of autopsy material from 22 subjects (19 male, three female), between 18 and 63 years of age. The specimens comprised the anterior part of median palate (APMP) from about 7 mm behind the incisive foramen (first premolar regions), the middle part of median palate (MPMP, second premolar region), and the posterior part of the median palate (PPMP, first molar region). They were prepared in the transversal plane using ground-thin-section technology. The midpalatal areas of the different part…

AdultMalePalate HardYounger ageBone densityAdolescentDentistryHard tissueMandibular first molarYoung AdultBone DensityBone Marrowparasitic diseasesBone qualityPremolarmedicineCadaverOrthodontic Anchorage ProceduresHumansIncisive foramenDental Implantsbusiness.industryAge FactorsCranial SuturesMiddle Agedmedicine.anatomical_structureFemaleOral SurgerybusinessBone volumeClinical oral implants research
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Morphological characteristics of microcirculation in oral lichen planus involving the lateral border of the tongue.

2009

Oral lichen planus (OLP) is a chronic mucosal condition commonly encountered in dental practice. Lichen planus is believed to represent an abnormal immune response in which epithelial cells are recognized as foreign, secondary to changes in the antigenicity of the cell surface. It has various oral manifestations. The aim of the study was to evaluate the morphological characteristics of microcirculation of lingual lichen planus (LLP). Twenty patients (10 patients with LLP and 10 healthy patients) were examined by means of videocapillaroscopy. The left margin of the lingual mucosa was examined in each patient. The capillary loop length, loop diameter, and capillary density were analyzed on ev…

AdultMalePathologymedicine.medical_specialtyVideo RecordingBiologyMicrocirculationMicroscopic AngioscopyTongue Diseasesstomatognathic systemSettore MED/28 - Malattie OdontostomatologicheTongueoral lichen tongue capillaroscopymedicineHumansStatistical analysisskin and connective tissue diseasesGeneral DentistryAgedNeovascularization PathologicLingual mucosaMicrocirculationMouth MucosaMiddle Agedmedicine.diseaseLoop lengthLateral borderCapillariesstomatognathic diseasesmedicine.anatomical_structureCapillary densityCase-Control StudiesOral lichen planusFemaleLichen Planus OralJournal of oral science
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Metabolic Evaluation of 94 Patients 5 to 16 Years After Ileocecal Pouch (Mainz Pouch 1) Continent Urinary Diversion

2003

PURPOSE In continent urinary diversion metabolic disturbances may be encountered in long-term followup. We evaluated metabolic consequences in patients with a minimum followup of 5 years after Mainz pouch 1 urinary diversion.At our institution continent urinary diversion using the ileocecal segment was performed between 1983 and 1995 in 458 patients. A total of 94 patients with an ileocecal pouch for a minimum of 5 years were reevaluated for metabolic changes. Median followup was 9.0 years. Routine laboratory parameters, blood gas analysis, vitamin B12, vitamin D25, cross-laps, bone specific alkaline phosphatase, osteocalcin and propeptide of type I collagen were obtained. Bone density was …

AdultMalePhosphopeptidesmedicine.medical_specialtyBone diseaseBone densityUrologymedicine.medical_treatmentUrinary systemOsteocalcinOsteoporosisSodium CitratePostoperative ComplicationsCalcitriolBone DensityReference ValuesPotassium CitrateHumansMedicineCitratesMegaloblastic anemiaAgedbusiness.industryUrinary Reservoirs ContinentUrinary diversionMiddle AgedAlkaline Phosphatasemedicine.diseaseSurgeryVitamin B 12FemaleCollagenBlood Gas AnalysisPouchAcidosisEnergy MetabolismbusinessContinent Urinary DiversionProcollagenFollow-Up StudiesJournal of Urology
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Force and EMG power spectrum during eccentric and concentric actions

2000

This study was designed to examine the force and activation levels of elbow flexor muscles during preactivated eccentric, concentric and isometric actions.Force, average EMG (aEMG), and the EMG power spectrum were investigated at different constant movement velocities (1 rad x s(-1), 2 rad x s(-1), 3 rad x s(-1), and 4 rad x s(-1)) at different joint angles.Average force at a 110 degree elbow angle was lower and aEMG was higher in concentric actions as compared with eccentric and isometric actions. At a 55 degree elbow angle, there was no difference in aEMG, or it was slightly higher in eccentric actions. MF was higher in the concentric as compared with eccentric actions at the three fastes…

AdultMalePhysicsmedicine.medical_specialtyElbow flexormedicine.diagnostic_testElectromyographyMovementElbowSpectral densityPhysical Therapy Sports Therapy and RehabilitationElectromyographyAnatomyConcentricMotor unitmedicine.anatomical_structurePhysical medicine and rehabilitationIsometric ContractionElbowmedicineHumansEccentricOrthopedics and Sports Medicinemedicine.symptomMuscle contractionMedicine &amp; Science in Sports &amp; Exercise
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Serum low density lipoprotein subclasses in asthma

2013

Summary Background The levels of serum low-density lipoproteins (LDL) have been implicated in the inflammatory cascade in a murine model of asthma. Recent findings suggest that LDL may modulate the inflammatory state of the asthmatic airways in humans. Objective We explored whether LDL subclasses are associated with the occurrence and severity of asthma. Methods 24 asthmatics (M/F: 11/13) and 24 healthy individuals, with normal BMI and absence of metabolic syndrome, matched for age and gender. Serum concentrations of LDL subclasses were distributed as seven bands (LDL-1 and -2 defined as large, least pro-inflammatory LDL, and LDL-3 to −7 defined as small, most pro-inflammatory LDL), using t…

AdultMalePulmonary and Respiratory Medicinemedicine.medical_specialtyVital CapacityAsthma pathogenesiPilot ProjectsSettore MED/10 - Malattie Dell'Apparato RespiratorioFEV1Forced Expiratory VolumeInternal medicineStatistical significanceAsthma pathogenesisHumansMedicineAgedAsthmaLDL subclassesAged 80 and overDyslipidemia; Asthma pathogenesis; FEV1; LDL subclassesbusiness.industryMiddle AgedSerum concentrationHypolipoproteinemiasmedicine.diseaseAsthmaLipoproteins LDLEndocrinologyDyslipidemiaMurine modelInflammatory cascadeFemaleSerum low density lipoproteinlipids (amino acids peptides and proteins)Metabolic syndromebusinessDyslipidemiaRespiratory Medicine
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