Search results for "Depression"
showing 10 items of 1778 documents
Temporal Profile of Gene Induction After Venous Ischemia and Effects of Spreading Depression
2004
Occlusion of two adjacent cortical veins is followed by a widespread reduction of rCBF and the occurrence of small infarcts, which become larger if spreading depression (SD) occurs. The infarct matures over time with TUNEL-positive cells seen in the penumbra up to 4 days after vein occlusion. Caspase inhibition with zVAD.fmk reduces infarct size. Here, the time course of gene expression in the penumbra is compared to that induced by SD alone.
Stratified exercise therapy by physical therapists in primary care is feasible in patients with knee osteoarthritis
2018
Background There is strong evidence that exercise therapy is effective in reducing pain and activity limitations in knee osteoarthritis (OA), but effect sizes are low to moderate. Stratified exercise therapy tailored to clinically relevant subgroups of patients is expected to optimise treatment effects in a cost-effective manner. Objectives This study aimed to explore the feasibility of a newly developed model of stratified exercise therapy in primary care. Methods A mixed method design was used, consisting of an uncontrolled pretest-posttest design and a process evaluation. Eligible patients visiting a participating primary care physical therapist (PT) were included. Based on our model, pa…
Spanish consensus on the physical health of patients with depressive disorders
2014
Comorbidity between depression and physical illnesses is very common and has a significant impact on the health and management of the patient. With the support of the Sociedades Espanolas de Psiquiatria y Psiquiatria Biologica, and Sociedad Espanola de Medicos de Atencion Primaria (SEMERGEN) a consensus was prepared on physical health in patients with depression and is summarized in the present work. The literature review highlighted the high frequency of cardiovascular and endocrine-metabolic disorders in patients with depression such as diabetes and obesity, thus making the primary and secondary prevention recommendations for patients with cardiovascular or metabolic risk applicable to pa…
Why do antidepressant therapies have such a poor success rate?
2016
Major depression is one of the leading global diseases [1,2]. Treatment is required, because untreated patients suffer not only from impaired emotion [3,4], but also from cognitive [4–6] and somati...
THU0715-HPR Stratified exercise therapy by physical therapists in primary care is feasible in patients with knee osteoarthritis
2018
Background There is strong evidence that exercise therapy is effective in reducing pain and activity limitations in knee osteoarthritis (OA), but effect sizes are low to moderate. Stratified exercise therapy tailored to clinically relevant subgroups of patients is expected to optimise treatment effects in a cost-effective manner. Objectives This study aimed to explore the feasibility of a newly developed model of stratified exercise therapy in primary care. Methods A mixed method design was used, consisting of an uncontrolled pretest-posttest design and a process evaluation. Eligible patients visiting a participating primary care physical therapist (PT) were included. Based on our model, pa…
AB0715 THE PREVALENCE OF FIBROMIYALGIA IN PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER AND THE RELATIONSHIP BETWEEN FATIGUE AND QUALITY OF LIFE
2021
Background:Familial Mediterranean Fever (FMF) can cause various muscle diseases. Because it is a chronic auto inflammatory disease, painful trigger points may be encountered in the examination due to a decrease in the pain threshold (1-3).Objectives:The aim of this study was to determine the prevalence of Fibromiyalgia in patients with FMF, at the same time to identify the relationship between fatigue and quality of life.Methods:Sixtyseven patients (38 female, 29 male) with FMF were enrolled in the study. They were diagnosed with FMF based on the Livneh diagnostic criteria (4). Fibromyalgia involvement of the patients was evaluated according to the Fibromyalgia Impact Questionnaire (FIQ). P…
Psychosomatische Medizin in der Gutenberg- Gesundheitsstudie (GHS) – Fragestellungen, Messverfahren, ausgewählte Ergebnisse
2020
Psychosomatic medicine in the Gutenberg Health Study (GHS) - research questions, measurement instruments, selected results Goal: Main questions from the Gutenberg Health Study (GHS) related to psychosomatic medicine are presented: (1) Prevalence and incidence of mental illnesses, (2) Sex-specific risk- and protective factors for mental health, (3) Interplay between psychological and somatic diseases and (4) methodical-psychometric developments. Methods: The GHS is an ongoing, prospective and interdisciplinary cohort study in Mainz. The comprehensive examinations include psychological characteristics and clinical and laboratory tests. 15010 respondents were selected in the baseline study fro…
PS-075 Evaluation of fall risks in elderly patients
2014
Background Falls among hospitalised elderly patients are a major public health concern since they can cause loss of independence, injury and sometimes patient death. Purpose To examine risk factors, especially drugs, potentially related to falls in elderly patients and to define possible actions. Materials and methods A retrospective (May 1 2010–March 31 2013) study was performed at ISMETT, a 90-bed hospital. Patient characteristics (age/gender/body mass index, BMI), clinical conditions (diagnosis/comorbidity), ward (Intensive Care Unit, Step-Down Unit, Cardiothoracic Surgery Unit and Abdominal Surgery Unit), length of stay, number of medicines taken within three days before falling and sev…
Consenso español de salud física del paciente con depresión
2014
Comorbidity between depression and physical illnesses is very common and has a significant impact on the health and management of the patient. With the support of the Sociedades Espanolas de Psiquiatria y Psiquiatria Biologica, and Sociedad Espanola de Medicos de Atencion Primaria (SEMERGEN) a consensus was prepared on physical health in patients with depression and is summarized in the present work. The literature review highlighted the high frequency of cardiovascular and endocrine-metabolic disorders in patients with depression such as diabetes and obesity, thus making the primary and secondary prevention recommendations for patients with cardiovascular or metabolic risk applicable to pa…
Psychische Komorbidität, Inanspruchnahme- und Gesundheitsverhalten bei Übergewichtigen und Adipösen - am Beispiel einer repräsentativen Stichprobe de…
2007
Obesity is associated with an increased somatic morbidity and mortality. This paper focuses on the controversial issue of mental co-morbidity in various populations of overweight and obese persons and the relationship to the utilization of medical care and health behaviour. Therefore, this paper focuses on health care utilization and health behaviour in overweight/obese with mental co-morbidity. In a representative German community sample with n = 1281 we administered valid self-rating scales on depression and anxiety. Using established cut-off scores we identified 61 subjects with both overweight/obesity and at least one mental disorder. Compared to the overweight/obese without mental co-m…