Search results for "Derivative"

showing 10 items of 1074 documents

Study of the influence of temperature and precipitations on the levels of BTEX in natural waters.

2013

Assessment of seasonal changes in surface water quality is an important aspect for evaluating temporal variation of water due to natural or anthropogenic inputs of point and non-point sources. The objective of this paper was to investigate the influence of seasonal temperature fluctuations and precipitations on the levels of BTEX in natural waters. Principal component analysis (PCA) was used to evaluate the seasonal correlations of BTEX levels in water and to extract the parameters that are most important in assessing seasonal variations of water quality. This study was carried out as a part of VOCs monitoring program in natural water samples from Mediterranean coast. To carry out this proj…

Mediterranean climateEnvironmental EngineeringHealth Toxicology and MutagenesisRainBTEXlaw.inventionRiverslawBenzene DerivativesEnvironmental ChemistryFlame ionization detectorWaste Management and DisposalDetection limitPrincipal Component AnalysisChemistryMediterranean RegionTemperaturePollutionMonitoring programEnvironmental chemistryPrincipal component analysisGas chromatographyWater qualitySeasonsWater Pollutants ChemicalEnvironmental MonitoringJournal of hazardous materials
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EXACT SOLUTIONS FOR A CLASS OF FRACTAL TIME RANDOM WALKS

1995

Fractal time random walks with generalized Mittag-Leffler functions as waiting time densities are studied. This class of fractal time processes is characterized by a dynamical critical exponent 0<ω≤1, and is equivalently described by a fractional master equation with time derivative of noninteger order ω. Exact Greens functions corresponding to fractional diffusion are obtained using Mellin transform techniques. The Greens functions are expressible in terms of general H-functions. For ω<1 they are singular at the origin and exhibit a stretched Gaussian form at infinity. Changing the order ω interpolates smoothly between ordinary diffusion ω=1 and completely localized behavior in the …

Mellin transformApplied MathematicsGaussianMathematical analysisRandom walksymbols.namesakeFractalModeling and SimulationTime derivativeMaster equationsymbolsGeometry and TopologyLimit (mathematics)Critical exponentMathematicsFractals
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Characterization of two Lactococcus lactis zinc membrane proteins, Llmg_0524 and Llmg_0526, and role of Llmg_0524 in cell wall integrity

2015

Background Due to its extraordinary chemical properties, the cysteine amino acid residue is often involved in protein folding, electron driving, sensing stress, and binding metals such as iron or zinc. Lactococcus lactis, a Gram-positive bacterium, houses around one hundred cysteine-rich proteins (with the CX2C motif) in the cytoplasm, but only a few in the membrane. Results In order to understand the role played by this motif we focused our work on two membrane proteins of unknown function: Llmg_0524 and Llmg_0526. Each of these proteins has two CX2C motifs separated by ten amino-acid residues (CX2CX10CX2C). Together with a short intervening gene (llmg_0525), the genes of these two protein…

Microbiology (medical)Lysozymechemistry.chemical_elementZincPlasma protein bindingGrowthMicrobiologyMembrane proteins;Growth;Cumene hydroperoxideProtein structureBacterial ProteinsCumene hydroperoxideCell Wallcystéinelactococcus lactisMembrane proteinsBenzene Derivatives[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyCysteineBinding siteBinding SitesbiologyProtein StabilityLactococcus lactispropriété de membranebiology.organism_classificationcroissanceProtein Structure Tertiary3. Good healthZincchemistryBiochemistryMembrane proteinProtein foldingProtein BindingResearch ArticleCysteine
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Multidrug and broad-spectrum cephalosporin resistance among Salmonella enterica serotype enteritidis clinical isolates in southern Italy.

2002

ABSTRACT From 1992 to 1997, only six sporadic isolates of Salmonella enterica serotype Enteritidis from patients with cases of gastroenteritis in southern Italy exhibited resistance to broad-spectrum cephalosporins. Five isolates produced SHV-12, and one isolate encoded a class C β-lactamase. The bla SHV-12 gene was located in at least two different self-transferable plasmids, one of which also carried a novel class 1 integron.

Microbiology (medical)Serotypemedicine.drug_classEpidemiologySalmonella enteritidisCephalosporinIntegronbeta-LactamasesMicrobiologyPlasmidDrug Resistance Multiple BacterialGenotypemedicineHumansamoxicillin plus clavulanic acid; ampicillin; antibiotic agent; aztreonam; beta lactamase; cefotaxime; cefoxitin; ceftazidime; cephalosporin derivative; chloramphenicol; kanamycin; plasmid DNA; streptomycin; sulfonamide; tobramycin antibiotic resistance; article; bacterial infection; bacterium isolate; DNA probe; gastroenteritis; gastrointestinal infection; Italy; nonhuman; nucleotide sequence; phenotype; plasmid; priority journal; Salmonella; Salmonella enterica Base Sequence; beta-Lactamases; Cephalosporin Resistance; Cross Infection; Drug Resistance Multiple Bacterial; Gastroenteritis; Genes Bacterial; Humans; Italy; Plasmids; Salmonella enteritidis; Salmonella Infections Bacteria (microorganisms); Negibacteria; Salmonella; Salmonella entericaCephalosporin ResistanceCross InfectionbiologyBase SequenceCephalosporin Resistancebiochemical phenomena metabolism and nutritionbacterial infections and mycosesbiology.organism_classificationVirologyGastroenteritisItalySalmonella enteritidisSalmonella entericaGenes BacterialSalmonella Infectionsbiology.proteinPlasmidsJournal of clinical microbiology
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Anti-16-kilodalton mycobacterial protein immunoglobulin M levels in healthy but purified protein derivative-reactive children decrease after chemopro…

2007

ABSTRACT Serum responses against Mycobacterium tuberculosis HSP16 were determined for children with tuberculosis (TB) and for healthy purified protein derivative (PPD)-positive and PPD-negative children. Immunoglobulin G (IgG) and IgM responses were higher for TB patients than for other groups. After chemotherapy, IgM and IgG responses decreased for TB patients and PPD-positive subjects. Monitoring of anti- M. tuberculosis HSP16 responses could assist in the management of pediatric TB.

Microbiology (medical)TuberculosisAdolescentChaperoninsmedicine.medical_treatmentClinical BiochemistryImmunologyAntitubercular AgentsTuberculinEnzyme-Linked Immunosorbent AssayTuberculinChemopreventionImmunoglobulin GMicrobiologyKilodaltonMycobacterium tuberculosisBacterial ProteinsmedicineHumansTuberculosisImmunology and AllergyChildChemotherapyMycobacterium tuberculosis IgMpurified protein derivative chemoprophylaxisbiologybusiness.industryClinical and Diagnostic Laboratory ImmunologyMycobacterium tuberculosisbiology.organism_classificationmedicine.diseaseImmunoglobulin MImmunoglobulin MChild PreschoolImmunoglobulin GImmunologyChemoprophylaxisbiology.proteinbusiness
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Early root surface colonization by human periodontal ligament fibroblasts following treatment with different biomaterials

2013

The present in-vitro study examined the effects of different biomaterials on early root surface colonization by human periodontal ligament (PDL) fibroblasts using confocal-laser-scanning-microscopy (CLSM).Fifteen periodontally-diseased teeth were extracted, treated with scaling/root planing and longitudinally cut to obtain 30 root fragments. Fragments were treated either with 24% EDTA following application of enamel matrix derivative (EMD), 24% EDTA or EMD only, nanocrystalline hydroxyapatite (NHA) paste or oily calcium hydroxide suspension (OCHS) for 1 h each. The analogue untreated root specimens served as controls. Root fragments were incubated with human PDL fibroblasts and cellular pro…

Microscopy ConfocalRoot surfaceMorphology (linguistics)Calcium hydroxidePeriodontal LigamentChemistrybusiness.industryDentistryRoot planingBiocompatible MaterialsGeneral MedicineFibroblastsMolecular biologychemistry.chemical_compoundTreatment modalityEnamel matrix derivativeHumansPeriodontal fiberColonizationTooth RootbusinessGeneral DentistryActa Odontologica Scandinavica
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On the pyrolytic decomposition of cadmium carbonate

1996

The pyrolytic decomposition of cadmium carbonate was studied by thermogravimetry (TG), derivative thermogravimetry (DTG), differential thermoanalysis (DTA) and exoemission of electrons (EEE).

MineralogyDecompositionGibbs free energyThermogravimetrychemistry.chemical_compoundsymbols.namesakechemistryDifferential thermal analysisCadmium oxidesymbolsPyrolytic carbonPyrolysisDerivative (chemistry)Nuclear chemistryJournal of Thermal Analysis
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Approximations and Metric Regularity in Mathematical Programming in Banach Space

1993

This paper establishes verifiable conditions ensuring the important notion of metric regularity for general nondifferentiable programming problems in Banach spaces. These conditions are used to obtain Lagrange-Kuhn-Tucker multipliers for minimization problems with infinitely many inequality and equality constraints.

Minimisation (psychology)Mathematical optimizationGeneral MathematicsMathematics::Optimization and ControlConstrained optimizationBanach spaceSubderivativeManagement Science and Operations ResearchComputer Science Applicationssymbols.namesakeLagrange multiplierMetric (mathematics)symbolsVerifiable secret sharingMinificationMathematicsMathematics of Operations Research
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Inhibitory effects and oxidation of 6-methylcoumarin, 7-methylcoumarin and 7-formylcoumarin via human CYP2A6 and its mouse and pig orthologous enzymes

2015

1. Information about the metabolism of compounds is essential in drug discovery and development, risk assessment of chemicals and further development of predictive methods. 2. In vitro and in silico methods were applied to evaluate the metabolic and inhibitory properties of 6-methylcoumarin, 7-methylcoumarin and 7-formylcoumarin with human CYP2A6, mouse CYP2A5 and pig CYP2A19. 3. 6-Methylcoumarin was oxidized to fluorescent 7-hydroxy-6-methylcoumarin by CYP2A6 (Km: 0.64-0.91 µM; Vmax: 0.81-0.89 min(-1)) and by CYP2A5 and CYP2A19. The reaction was almost completely inhibited at 10 µM 7-methylcoumarin in liver microsomes of human and mouse, but in pig only 40% inhibition was obtained with the…

Models Molecular0301 basic medicineenzyme assayTime Factorscoumarin derivativecytochrome P450Health Toxicology and MutagenesisIn silicoSus scrofaHydroxylationToxicologyta3111BiochemistryCytochrome P-450 CYP2A6Inhibitory Concentration 50Mice03 medical and health sciencesCoumarinsmedicineAnimalsCytochrome P-450 Enzyme InhibitorsHumansCYP2A6ta317Pharmacologychemistry.chemical_classificationbiologyMethoxsalenta1182Cytochrome P450General MedicineMetabolismMolecular biologyIn vitroEnzyme assayKinetics030104 developmental biologyEnzymeBiochemistrychemistrybiology.proteinfluorescenceOxidation-Reductionmetabolismmedicine.drugXenobiotica
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Heterocyclic and Phenyl Double-Bond-Locked Combretastatin Analogues Possessing Potent Apoptosis-inducing activity in HL60 and in MDR Cell lines

2005

Two new series of combretastatin (CA-4) analogues have been prepared. The alkenyl motif of CA-4 was replaced either by a five-membered heterocyclic (isoxazoline or isoxazole) or by a six-membered ring (pyridine or benzene). The new compounds have been evaluated for their effects on tubulin assembly and for cytotoxic and apoptotic activities. Five compounds (18b, 20a, 21a, 34b, and 35b) demonstrated an attractive profile of cytotoxicity (IC501 microM) and apoptosis-inducing activity but poor antitubulin activity. The isoxazoline derivatives 18b, 20a, and 21a, demonstrated potent apoptotic activity different from that of natural CA-4. Their ability to block most cells in the G2 phase suggests…

Models MolecularA-4 ANALOGSDouble bondHL60StereochemistryPyridinesTUBULINApoptosisANTINEOPLASTIC AGENTSchemistry.chemical_compoundStructure-Activity RelationshipCell Line TumorDrug DiscoveryStilbenesBenzene DerivativesHumansIsoxazoleBIOLOGICAL EVALUATIONCytotoxicitychemistry.chemical_classificationCombretastatinbiologyCOLCHICINEDEATHIsoxazolesDrug Resistance MultipleTubulinANTIMITOTIC ANTITUMOR AGENTSMULTIDRUGchemistryApoptosisCell cultureDrug Resistance NeoplasmDISCOVERYbiology.proteinMolecular MedicineDrug Screening Assays AntitumorSOLID TUMOR-THERAPY
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