Search results for "Dermatology"
showing 6 items of 2026 documents
Oral pigmented lesions:a retrospective analysis from Brazil
2020
Background Pigmented lesions are uncommon in the oral mucosa, and studies investigating the incidence and types of these lesions are desired to improve the diagnostic knowledge of clinicians. The aim of this study was to analyze the distribution of oral pigmented lesions in a Brazilian population. Material and Methods A retrospective descriptive cross-sectional study was performed. Oral pigmented lesions were retrieved from the files of two oral and maxillofacial pathology services from Brazil over a 45-year period (1974-2019). The clinical data and the diagnoses of each case were retrieved and included in a Microsoft Excel® database. Results From 77.074 lesions diagnosed in this period, 76…
Reconstruction of a Lower Lip Defect with Bilateral Nasolabial Musculocutaneous Flap. Case Report
2020
Abstract Squamous cell carcinoma is the most common form of malignant tumour in the lower lip and its radical excision sometimes leads to complex defects. The treatment of squamous cell carcinoma of the lower lip is mainly surgical and consists of complete excision of the tumour, followed by immediate reconstruction. Although the nasolabial flap is a common flap used in the reconstruction of facial defects, it is an underestimated option in the reconstruction of the lower lip. We describe the reconstruction of a large defect of the lower lip that includes the bilateral commissures and ¼ of the upper lip, left side, in a 76-year-old male patient. Bilateral musculocutaneous nasolabial flap wa…
Lichen Planus: A Muco-Cutaneous, Nails and Scalp Disorder – Cases Report
2019
Abstract Lichen planus is an autoimmune, itching disorder that involves T lymphocytes, which may interest the skin, mucous membranes and exoskeletons. The presence of lichen manifestations both at the skin, mucous membranes and at the level of the skin attachments (hair and nails) is rarely mentioned in the literature. Although lichen planus may have a self-limiting evolution, early treatment is important in shortening the evolution of the disease and in controlling the symptoms. The therapeutic effects of retinoids (immunomodulatory, anti-inflammatory, anti-proliferative effects) make them an appropriate choice in the treatment of lichen with (cutaneous-mucosal, nail and planopilaris lesio…
Psoriasis and Its Impact on In-Hospital Outcome in Patients Hospitalized with Acute Kidney Injury
2020
Background: Psoriasis is a chronic inflammatory disease which affects the body far beyond the skin. Whereas there is solid evidence that chronic skin inflammation in psoriasis drives cardiovascular disease, the impact on renal impairment and acute kidney injury (AKI) is still unclear. We aimed to analyze the impact of psoriasis on the in-hospital outcome of patients hospitalized with AKI. Methods: In this retrospective database study, we investigated data on characteristics, comorbidities, and in-hospital outcomes for all hospitalized patients with AKI stratified for concomitant psoriasis, which were collected by the Federal Office of Statistics in Germany between 2005 and 2016. Results: Am…
Ultraviolet A1 radiation induces nitric oxide synthase-2 expression in human skin endothelial cells in the absence of proinflammatory cytokines.
2001
Skin exposure to ultraviolet radiation from sunlight causes erythema and edema formation as well as inflammatory responses. As some of these ultraviolet-induced effects are potentially mediated by nitric oxide synthases, we examined the role of cytokines and ultraviolet A 1 radiation (340–400 nm) on the expression of the nitric oxide synthase-2 in endothelia of normal human skin biopsies during short-term organ culture as well as expression and activity of the nitric oxide synthase-2 in in vitro cell cultures of human dermal endothelial cells. Both, cytokine challenge (interleukin-1β + tumor necrosis factor-α + interferon-γ) but also ultraviolet A 1 exposure (50 J per cm 2 ) in the absence …
Chemical Composition of the Essential Oil of Bupleurum Fontanesii (Apiaceae) Growing Wild in Sicily and its Activity on Microorganisms Affecting Hist…
2016
Hydrodistillation of the flowers (BpFl) of and fruits (BpFr) of Bupleurum fontanesii Guss. ex Caruel gave two oils that were analyzed by GC and GC-MS. The main components were α-elemol (16.7%), caryophyllene oxide (16.4%) and heptacosane (15.9%) in BpFl, and spathulenol (16.8%), caryophylladienol I (13.2%) and α-elemol (12.8%) in BpFr. A good antimicrobial activity against several microorganisms, including Bacillus subtilis, Staphylococcus aureus, Fusarium oxysporum and Aspergillus niger, all infesting historical art craft, was also determined.