Search results for "Design"

Smart Vision systems: adequacy architecture algorithm, design and hardware implementations

2013

Social Acceptance of a Teleoperated Android: Field Study on Elderly’s Engagement with an Embodied Communication Medium in Denmark

2012

We explored the potential of teleoperated android robots, which are embodied telecommunication media with humanlike appearances, and how they affect people in the real world when they are employed to express a telepresence and a sense of 'being there'. In Denmark, our exploratory study focused on the social aspects of Telenoid, a teleoperated android, which might facilitate communication between senior citizens and Telenoid's operator. After applying it to the elderly in their homes, we found that the elderly assumed positive attitudes toward Telenoid, and their positivity and strong attachment to its huggable minimalistic human design were cross-culturally shared in Denmark and Japan. Cont…

Human exome and mouse embryonic expression data implicate ZFHX3, TRPS1, and CHD7 in human esophageal atresia

2020

Introduction Esophageal atresia with or without tracheoesophageal fistula (EA/TEF) occurs approximately 1 in 3.500 live births representing the most common malformation of the upper digestive tract. Only half a century ago, EA/TEF was fatal among affected newborns suggesting that the steady birth prevalence might in parts be due to mutational de novo events in genes involved in foregut development. Methods To identify mutational de novo events in EA/TEF patients, we surveyed the exome of 30 case-parent trios. Identified and confirmed de novo variants were prioritized using in silico prediction tools. To investigate the embryonic role of genes harboring prioritized de novo variants we perfor…

Product development process in Spanish SMEs: an empirical research

2002

Rapid product development has been treated as a competitive strategy in a global market environment. It is essential to improve the product development process with the objective of reducing product development cycle time and hence to reach the market as quickly as possible. Large-scale companies have adopted new strategies and technologies to reduce the product development cycle time, taking into account various market and innovation barriers. However, small and medium enterprises (SMEs) have not received adequate attention from researchers for their product development process. In this paper, an attempt has been made to analyze the critical success factors for the product development proc…

An AER handshake-less modular infrastructure PCB with x8 2.5Gbps LVDS serial links

2014

Nowadays spike-based brain processing emulation is taking off. Several EU and others worldwide projects are demonstrating this, like SpiNNaker, BrainScaleS, FACETS, or NeuroGrid. The larger the brain process emulation on silicon is, the higher the communication performance of the hosting platforms has to be. Many times the bottleneck of these system implementations is not on the performance inside a chip or a board, but in the communication between boards. This paper describes a novel modular Address-Event-Representation (AER) FPGA-based (Spartan6) infrastructure PCB (the AER-Node board) with 2.5Gbps LVDS high speed serial links over SATA cables that offers a peak performance of 32-bit 62.5…

Adaptive Sequential Interpolator Using Active Learning for Efficient Emulation of Complex Systems

2020

Many fields of science and engineering require the use of complex and computationally expensive models to understand the involved processes in the system of interest. Nevertheless, due to the high cost involved, the required study becomes a cumbersome process. This paper introduces an interpolation procedure which belongs to the family of active learning algorithms, in order to construct cheap surrogate models of such costly complex systems. The proposed technique is sequential and adaptive, and is based on the optimization of a suitable acquisition function. We illustrate its efficiency in a toy example and for the construction of an emulator of an atmosphere modeling system.

Derivatives of Erythropoietin That Are Tissue Protective But Not Erythropoietic

2004

Erythropoietin (EPO) is both hematopoietic and tissue protective, putatively through interaction with different receptors. We generated receptor subtype–selective ligands allowing the separation of EPO's bioactivities at the cellular level and in animals. Carbamylated EPO (CEPO) or certain EPO mutants did not bind to the classical EPO receptor (EPOR) and did not show any hematopoietic activity in human cell signaling assays or upon chronic dosing in different animal species. Nevertheless, CEPO and various nonhematopoietic mutants were cytoprotective in vitro and conferred neuroprotection against stroke, spinal cord compression, diabetic neuropathy, and experimental autoimmune encephalomyeli…

Endoscopic surgery of the rhinobasis with a computer-assisted localizer

1996

The endoscope is useful for the diagnosis and surgical therapy of diseases of the nose, the paranasal sinuses and its neighboring regions, and allows for microinvasive, functional approaches. The reduced invasiveness of therapeutic procedures is sometimes accompanied by insufficient clearness of the surgical field, however. This significant problem is solved by the computer-assisted-surgery (CAS) system, an intraoperative localizer. It allows continuous orientation based on three-dimensional reconstructed preoperative CT scans with superimposed positioning of the endoscope. We have now adapted CAS for endoscopic sinus surgery, which meant that a variety of visualization methods were tested.…

Advances in endoscopic imaging of colorectal neoplasia.

2010

Colon cancer screening is arguably the most important activity performed by gastroenterologists. Recent decreases in rates of death from colorectal cancer indicate that screening methods such as colonoscopy have a positive impact. There is still room for improvement, however, particularly in prevention of right-sided colon cancer. Practice issues, such as making colonoscopy more comfortable, safer, and less costly, are keys to continued success in cancer prevention. Colonoscopy techniques, technologies, and quality control measures have advanced to improve detection, classification, and removal of early neoplasias. In particular, slow, careful inspection of the colon by gastroenterologists …

Closed-form solutions of the energy balance equation for drip laterals under the Darcy-Weisbach resistance formula

2018

Many studies have investigated easy methods to design drip laterals, as well as the best resistance equation to use, which is fundamental to accurately account for friction losses. This paper addresses both the features of lateral design relationships and the influence of the friction-loss equation on the design variables. First, simple closed-form solutions of the energy balance equation for both sloped and horizontal drip laterals are derived with the simplified Darcy-Weisbach resistance formula by assuming the Darcy friction factor as invariant versus the Reynolds number. Second, an error analysis is performed assuming the friction factor as constant in the design, which is compared to u…