Search results for "Design"
showing 10 items of 5885 documents
Effects of temperature, pH and sugar concentration on the growth parameters of Saccharomyces cerevisiae, S. kudriavzevii and their interspecific hybr…
2008
The effects of temperature, pH and sugar concentration (50% glucose + 50% fructose) on the growth parameters of Saccharomyces cerevisiae T73, S. kudriavzevii IFO 1802T and the hybrid strain S. cerevisiae × S. kudriavzevii W27 were studied by means of response surface methodology based in a central composite circumscribed design. Lag phase could not be properly modelled in the wine model system, where yeasts started the fermentation in few hours after inoculation. In the case of the maximum specific growth rate (μ max), the temperature was the most important variable for three yeasts, although the effects of sugar concentration (in T73 and W27) and pH (W27 and 1802) were also significan…
Comparison of simultaneous saccharification and fermentation and separate hydrolysis and fermentation processes for butanol production from rice straw
2020
Abstract Rice straw (RS) is one of the lignocellulosic wastes with the highest global production. The main objective of this study was to maximise the butanol production by Clostridium beijerinckii DSM 6422 from RS pretreated by microwave-assisted hydrothermolysis. Two different fermentation strategies were compared: separate hydrolysis and fermentation (SHF, two-step process) and simultaneous saccharification and fermentation (SSF, one-step process). In parallel, the variables that significantly affected the butanol production were screened by using fractional factorial designs. Butanol concentration and productivity at 48 h were, respectively, 8% and 173% higher in SSF than in SHF. A one-…
Production of Cultural Policy in Russia: Authority and Intellectual Leadership
2020
The paper discusses different frameworks of knowledge production within the discourses and practices of Russian cultural policy. Russian cultural policy as an administrative sector has been developed in line with two distinctive governmental regimes, more precisely during the period of liberal decentralisation of the 1990s and the conservative centralisation from 2011 up until today. The study focuses on the main changes that have occurred in the framework of policy design and participation in policy-making. An attempt is made to combine Foucauldian analytical frameworks of power and discourse with a Gramscian hegemonic approach to political studies that was mainly advocated by the Essex sc…
Immediate Nonfunctional Loading of NobelPerfect Implants in the Anterior Dental Arch in Private Practice - 5-Year Data
2012
Background: The concept of scalloped implants to maintain the natural contour of the alveolar ridge has been a source of controversy for many years. Purpose: This study examined the long-term clinical performance of the scalloped NobelPerfect implant in a one-stage procedure (immediate loading in the esthetic zone). Materials and Methods: In 20 patients, immediate prosthetic restorations were placed on 31 NobelPerfect implants in a private practice and followed for up to 78 months. Twenty-one implants were placed immediately after extraction, seven implants were placed after osseous consolidation of the extraction sockets, and three implants were placed secondary to extended alveolar ridge …
A prospective, multi-center, practice-based cohort study on all-ceramic crowns
2021
The aim of this prospective, multi-center, practice-based cohort study was to analyze factors associated with the success of all-ceramic crowns.All-ceramic crowns placed in a practice-based research network ([Ceramic Success Analysis, AG Keramik) were analyzed. Data from 1254 patients with (mostly in-office CAD/CAM) all-ceramic crowns placed by 101 dentists being followed up for more than 5 years were evaluated. At the last follow-up visit crowns were considered as successful (not failed) if they were sufficient, whereas crowns were considered as survived (not lost) if they were still in function. Multi-level Cox proportional hazards models were used to evaluate the association between a ra…
Resistance to bond degradation between dual-cure resin cements and pre-treated sintered CAD-CAM dental ceramics
2012
Objective: To evaluate the bond stability of resin cements when luted to glass-reinforced alumina and zirconia CAD/CAM dental ceramics. Study design: Eighteen glass-infiltrated alumina and eighteen densely sintered zirconia blocks were randomly conditioned as follows: Group 1: No treatment; Group 2: Sandblasting (125 µm Al2O3-particles); and Group 3: Silica-coating (50 µm silica-modified Al2O3-particles). Composite samples were randomly bonded to the pre-treated ceramic surfaces using different resin cements: Subgroup 1: Clearfil Esthetic Cement (CEC); Subgroup 2: RelyX Unicem (RXU); and Subgroup 3: Calibra (CAL). After 24 h, bonded specimens were cut into 1 ± 0.1 mm2 sticks. One-half of th…
Bioactive Glass-Ceramics in Middle Ear Surgery An 8-Year Review
1988
An 8-year follow-up of Ceravital middle ear prostheses showed there was extremely good tolerance in the middle ear space. Incompatibility phenomena were not observed, and inflammatory reactions were neither caused nor supported by the implants. The tympanoplasties were always performed without interposition of cartilage between the tympanic membrane or the tympanic membrane graft and the disk-shaped portion of the implant, and extrusions were never observed. Long-lasting inflammatory processes appeared to destroy implants the same way they destroy ossicles. Transient inflammatory periods (such as episodes of purulent otitis media, which occurred soon after the prostheses were implanted) did…
New polyamine drugs as more effective antichagas agents than benznidazole in both the acute and chronic phases.
2018
Abstract Despite the continuous research effort that has been made in recent years to find ways to treat the potentially life threatening Chagas disease (CD), this remains the third most important infectious disease in Latin America. CD is an important public health problem affecting 6–7 million people. Since the need to search for new drugs for the treatment of DC persists, in this article we present a panel of new polyamines based on the tripodal structure of tris(2-aminomethyl)amine (tren) that can be prepared at low cost with high yields. Moreover, these polyamines present the characteristic of being water-soluble and resistant to the acidic pH values of stomach, which would allow their…
Negative-pressure cavitation coupled with aqueous two-phase extraction and enrichment of flavonoids and stilbenes from the pigeon pea leaves and the …
2015
Abstract An efficient extraction method, negative-pressure cavitation coupled with aqueous two-phase extraction (NPC-ATPE), was developed to simultaneously extract and enrich flavonoids and stilbenes from pigeon pea leaves. The main bioactive compounds, cajaninstilbene acid (CSA), longistyline C (LLC), pinostrobin (PI) and pinostrobin chalcone (PIC) were chosen as target compounds. The extraction conditions were optimized using central composite design combined with response surface methodology. The optimized conditions were: concentration of (NH 4 ) 2 SO 4 21% (w/w), concentration of ethanol 23% (w/w) and temperature 30 °C, negative pressure −0.06 MPa, extraction time 30 min and the liquid…
Synthesis and anti-inflammatory activity of chalcone derivatives
1998
Chalcones and their derivatives were synthesized and evaluated for their anti-inflammatory activity. In vitro, chalcones 2, 4, 8, 10 and 13 inhibited degranulation and 5-lipoxygenase in human neutrophils, whereas 11 behaved as scavenger of superoxide. Only four compounds (4-7) inhibited cyclo-oxygenase-2 activity. The majority of these samples showed anti-inflammatory effects in the mouse air pouch model.