Search results for "Development"
showing 10 items of 26949 documents
Bright spots in the darkness of cancer: A review of starfishes-derived compounds and their anti-tumor action
2019
The fight against cancer represents a great challenge for researchers and, for this reason, the search for new promising drugs to improve cancer treatments has become inevitable. Oceans, due to their wide diversity of marine species and environmental conditions have proven to be precious sources of potential natural drugs with active properties. As an example, in this context several studies performed on sponges, tunicates, mollusks, and soft corals have brought evidence of the interesting biological activities of the molecules derived from these species. Also, echinoderms constitute an important phylum, whose members produce a huge number of compounds with diverse biological activities. In…
Collective Locomotion of Human Cells, Wound Healing and Their Control by Extracts and Isolated Compounds from Marine Invertebrates
2020
The collective migration of cells is a complex integrated process that represents a common theme joining morphogenesis, tissue regeneration, and tumor biology. It is known that a remarkable amount of secondary metabolites produced by aquatic invertebrates displays active pharmacological properties against a variety of diseases. The aim of this review is to pick up selected studies that report the extraction and identification of crude extracts or isolated compounds that exert a modulatory effect on collective cell locomotion and/or skin tissue reconstitution and recapitulate the molecular, biochemical, and/or physiological aspects, where available, which are associated to the substances und…
Challenges in Marketing Communications During the COVID-19 Pandemic
2022
The purpose of this study is to explore how tourism and hospitality firms managed marketing communications (marcom) since the COVID-19 outbreak and to propose a conceptual framework on marcom challenges that the pandemic crisis has brought to the industry. In-depth interviews were conducted with tourism and hospitality managers in Croatia, a destination that registered remarkable tourism results in 2021. The proposed conceptual framework reflects the adaptation process and major changes in B2B and B2C communication since the COVID-19 outbreak on one hand and resulting strategic opportunities for marcom managers on the other, discussed in terms of practical implications. To the best of the a…
Les stratégies de développement touristique des territoires de l’espace Rhin-Rhône : une nouvelle cohérence impulsée par le TGV
2012
International audience; The eastern branch of the Rhine-Rhône highspeed line was opened on 11th December 2011. It offers new connections in France and in Europe. Relationships between transport and economic development has often been studied in the literature. This article is an analysis of the relationship between transport, tourism and territory based on the promotion campaigns and the tourism development strategies in the territories newly connected by the high-speed line. Local projects have been catalogued and regional players have been interviewed in order to show how this new infrastructure can be appropriated to enhance the territorial reputation. An analysis of the current cooperat…
Unrooting inequality from development : recognition and justification of inequality in global development
2017
How does the tension resolve between a moral order with egalitarian imperatives, such as sustainable and inclusive human development, and a global political economy based on a market system that prioritizes meeting the wants and needs of those with purchasing power? By developing a comprehensive theoretical framework as analytical contribution, I propose to rethink a practice-intensive field (Development and International Cooperation) and analyze the texts that represent the dominant discourse in development policies: the UNDP Human Development Reports and the World Bank’s World Development Reports. These influential institutions have shaped the rise of neoliberalism as a hegemonic developm…
School burnout, depressive symptoms and engagement : Their combined effect on student achievement
2017
Abstract Prior studies have shown that student burnout becomes more prevalent during adolescence and is associated with both depressive symptoms and school engagement. Little is known about how burnout, engagement, and depressive symptoms jointly affect students’ school achievement in terms of grades and skipping class. The main purpose of the current study was to analyse these variables within a full model in order to examine the direct and indirect effects of burnout, engagement and depression on student achievement, while controlling for gender and age. Participants were 210 Italian high school students aged 14 to 16. Student burnout was found to exert the strongest effect on school achi…
Job Insecurity and Depressive Symptoms in Mothers and Adolescents: A Dyadic Study
2021
AbstractIn this study, we examined whether maternal perceived job insecurity (JI) affected depressive symptoms in their adolescent children. Specifically, we tested a mediator-moderator model in which we hypothesized that maternal JI was related to adolescent depressive symptoms indirectly via maternal depressive symptoms. Most importantly, we also explored whether this indirect path was moderated by two buffering resources, i.e., maternal off-job recovery and adolescent self-esteem. There is little research on the effects of parental JI on adolescent children from the viewpoint of buffering moderators. Due to growing insecurity in the labor markets we need more information about resources …
Brain responses to sound intensity changes dissociate depressed participants and healthy controls.
2017
Depression is associated with bias in emotional information processing, but less is known about the processing of neutral sensory stimuli. Of particular interest is processing of sound intensity which is suggested to indicate central serotonergic function. We tested weather event-related brain potentials (ERPs) to occasional changes in sound intensity can dissociate first-episode depressed, recurrent depressed and healthy control participants. The first-episode depressed showed larger N1 amplitude to deviant sounds compared to recurrent depression group and control participants. In addition, both depression groups, but not the control group, showed larger N1 amplitude to deviant than standa…
Attentional bias towards interpersonal aggression in depression – an eye movement study
2020
Depressed individuals exhibit an attentional bias towards mood-congruent stimuli, yet evidence for biased processing of threat-related information in human interaction remains scarce. Here, we tested whether an attentional bias towards interpersonally aggressive pictures over interpersonally neutral pictures could be observed to a greater extent in depressed participants than in control participants. Eye movements were recorded while the participants freely viewed visually matched interpersonally aggressive and neutral pictures, which were presented in pairs. Across the groups, participants spent more time looking at neutral pictures than at aggressive pictures, probably reflecting avoidanc…
A meta-analysis of the relation between RAN and mathematics.
2017
Several studies have shown that rapid automatized naming (RAN) is a significant predictor of mathematics, but the nature of their relationship remains elusive. Thus, the purpose of this meta-analysis was to estimate the size of their relationship and determine the conditions under which they correlate. We used a random-effects model analysis of data from 38 studies (33 unique samples, 151 correlations, 7,135 participants) to examine the size of the RAN–mathematics relationship and the role of different moderators (i.e., math measure and variable, type of RAN task, math age, study design, and sample characteristics). The results showed a significant correlation between RAN and mathematics (r…