Search results for "Diabetes mellitus."

Rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes): A multicenter retrospective nationwide Italian study a…

2017

Background Randomized controlled trials (RCTs) in the field of diabetes have limitations inherent to the fact that design, setting, and patient characteristics may be poorly transferrable to clinical practice. Thus, evidence from studies using routinely accumulated clinical data are increasingly valued. Aims We herein describe rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes), a multicenter retrospective nationwide study conducted at 50 specialist outpatient clinics in Italy and promoted by the Italian Diabetes Society. Data synthesis The primary objective of the study is to describe the baseline clinical characteristics (particularly HbA1c) of pa…

Efficacy and safety of photodynamic therapy with RLP068 for diabetic foot ulcers: a review of the literature and clinical experience

2020

This article is the second part of a literature review concerning diabetic foot ulcers (DFUs) and the use of antimicrobial photodynamic therapy (PDT). PDT involves the topical application of a photosensitiser into the tissue, followed by illumination that induces the formation of reactive oxygen species (ROS). PDT provides bacterial inactivation and promotes wound healing, and it can be used to manage the infection and microbial colonisation of DFUs. It has pivotal advantages in comparison with chemotherapeutics, such as no potential to induce resistance, and a wide spectrum of activity. Tetracationic Zn(II) phthalocyanine derivatives have been developed for PDT. Among these, we would like …

COVID-19 in Severe Asthma Network in Italy (SANI) patients: Clinical features, impact of comorbidities and treatments

2020

To the Editor Since the end of February 2020 Italy, first non- Asian Country, has reported an ever increasing number of COronaVIrus Disease 19 (COVID-19) patients, which has reached over 200,000 confirmed Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) infected subjects and resulted in more than 34000 deaths (data updated to June 19th, 20201).Patients with asthma are potentially more severely affected by by SARS-CoV-2 infection 2 and it is well established that respiratory viral infections are associated with severe adverse outcomes in patients with asthma, including increased risk of asthma exacerbation episodes 3. Nonetheless, according to the epidemiological studies publishe…

The relationship between context, structure, and processes with outcomes of 6 regional diabetes networks in Europe

2018

BackgroundWhile health service provisioning for the chronic condition Type 2 Diabetes (T2D) often involves a network of organisations and professionals, most evidence on the relationships between the structures and processes of service provisioning and the outcomes considers single organisations or solo practitioners. Extending Donabedian's Structure-Process-Outcome (SPO) model, we investigate how differences in quality of life, effective coverage of diabetes, and service satisfaction are associated with differences in the structures, processes, and context of T2D services in six regions in Finland, Germany, Greece, Netherlands, Spain, and UK.MethodsData collection consisted of: a) systemat…

Elintapaohjauksen lähtökohtia korkeassa diabetesriskissä olevilla henkilöillä tyypin 2 diabeteksen ehkäisyn toimeenpanohankkeessa (D2D) : elintapaohj…

2012

Otrā tipa cukura diabēta pacientu līdzestība ārstēšanā un aprūpē

2020

Bakalaura darba tēma “Otrā tipa cukura diabēta pacientu līdzestība ārstēšanā un aprūpē”. Tēmas aktualitāti nosaka straujais cukura diabēta slimnieku skaita pieaugums pasaulē. Cukura diabēts ierindojas piektajā vietā pasaules izplatītāko mirstības cēloņu vidū, kā arī ir galvenais akluma, nieru mazspējas, infarkta, insulta un apakšējo ekstremitāšu amputācijas iemesls. Darba mērķis ir noskaidrot 2. tipa cukura diabēta pacientu līdzestību ārstēšanā un aprūpē. Pētījuma uzdevumi ir izpētīt zinātnisko literatūru par 2. tipa cukura diabētu un pacientu līdzestību ārstēšanās un atveseļošanās procesos. Raksturot Kalistas Rojas adaptācijas teoriju, un saistīt to ar pētījuma tēmu. Veikt pētījumu un inte…

Finnish diabetes‐related quality of life questionnaire for children and adolescents: Reliability and validity

2020

Aim To study the psychometric properties, reliability, and validity of the FinDiab quality of life questionnaire (FDQL), a strength‐oriented quality of life (QOL) questionnaire for children and adolescents with type 1 diabetes (T1D). Methods Participants were 215 youths with T1D (aged 10–17 years). They completed FDQL and comparison questionnaires (KINDL‐R and SDQ). Demographic and disease measures were collected from the participants’ medical records. The questionnaire’s psychometric properties were investigated. Construct validity was studied through principal component analysis using Promax rotation, reliability with alphas, and criterion and convergent validity with correlations between…