Search results for "Diabetic Retinopathy"

Pars-Plana-Vitrektomie bei diabetischen Traktionsamotiones mit Foramen

2000

PURPOSE: To evaluate results and prognostic factors of pars-plana vitrectomy (ppv) using membrane peeling and C2F6-gas for diabetic traction retinal detachments with a hole. METHODS: We retrospectively reviewed the healing course of 84 eyes, which were treated in this way consecutively (follow-up 6-32 month). C2F6 was always used in case of a retinal hole at the posterior pole or in the upper part of the eye. The influence of HBA1c, type of diabetes, preoperative visual acuity, preoperative laser-coagulation and macular status over treatment results and rate of complications were studied using multivariate logistic regression analysis. RESULTS: Preoperatively 56% of the eyes showed premacul…

Validation of Automated Screening for Referable Diabetic Retinopathy With an Autonomous Diagnostic Artificial Intelligence System in a Spanish Popula…

2020

Purpose: The purpose of this study is to compare the diagnostic performance of an autonomous artificial intelligence (AI) system for the diagnosis of referable diabetic retinopathy (RDR) to manual grading by Spanish ophthalmologists. Methods: Subjects with type 1 and 2 diabetes participated in a diabetic retinopathy (DR) screening program in 2011 to 2012 in Valencia (Spain), and two images per eye were collected according to their standard protocol. Mydriatic drops were used in all patients. Retinal images—one disc and one fovea centered—were obtained under the Medical Research Ethics Committee approval and de-identified. Exams were graded by the autonomous AI system (IDx-DR, Coralville, Io…

2015

Objective Diabetic retinopathy (DR) is the leading cause of blindness in people of working age. The purpose of this paper is to report the prevalence and cardiovascular associations of diabetic retinopathy and maculopathy (DMac) in Germany.

Outcomes of Diabetic Retinopathy Post-Bariatric Surgery in Patients with Type 2 Diabetes Mellitus

2021

Bariatric surgery is an emerging therapeutic approach for obese type 2 diabetes mellitus (T2DM) patients, with proven benefits for achieving target glucose control and even remission of diabetes. However, the effect of bariatric surgery upon diabetic retinopathy is still a subject of debate as some studies show a positive effect while others raise concerns about potential early worsening effects. We performed a systematic review, on PubMed, Science Direct, and Web of Science databases regarding the onset and progression of diabetic retinopathy in obese T2DM patients who underwent weight-loss surgical procedures. A total of 6375 T2DM patients were analyzed. Most cases remained stable after b…

282 Ophtalmologic follow-up of diabetic patients managed by Gps or diabetologists: results of FOCUS survey

2011

ObjectiveTo describe the ophthalmological follow up and cardiologists-nephrologists’ involvements in diabetic patients managed by GPs or diabetologists.MethodsTransversal and observational survey conducted in 2009, by 1112 GPs and 188 specialists.Results2577 diabetic patients (T1D or T2D) have been included; 63% were males, and mean age was 62 years. Mean diabetes duration was 10 years. Most of them were hypertensive (72%), 68% had a dyslipidemia and 30% a non proliferative diabetic retinopathy. Nearly all patients have been followed by ophthalmologists (70% have been seen once a year).In patients having a diabetic retinopathy (DR), treatments have been intensified in 80% of them with a vis…

Ocular angiogenesis: translating preclinical indications to successful clinical development

2004

Angiogenesis-related ocular diseases such as age-related macular degeneration (AMD) or diabetic retinopathy have a high socioeconomic impact in western countries and are the leading causes of blindness. Conventional treatment modalities for AMD are of limited success. Inhibition of new vessel formation and targeting of pathological vessels seem to be the best choice in AMD. A variety of animal models mimic the relevant aspects of choroidal neovascularisation (CNV) and allow for therapy screening. Preclinical and clinical studies show that a variety of different strategies are very promising. Stategies include inhibition or blocking of vascular endothelial growth factor, a key player in angi…

Efficacy and Safety of Subthreshold Micropulse Yellow Laser for Persistent Diabetic Macular Edema After Vitrectomy: A Pilot Study

2022

Aim: To examine the effect of subthreshold micropulse yellow laser (SMYL) on best-corrected visual acuity (BCVA), central macular thickness (CMT), and optical coherence tomography angiography (OCT-A) changes in eyes with persistent diabetic macular edema (DME) after pars plana vitrectomy (PPV) for tractional DME (TDME).Patients and Methods: In a comparative study, 95 eyes of 95 consecutive patients with persistent DME were prospectively enrolled. The SMYL group (54 eyes) was treated with SMYL 6 months after PPV, while the control group (41 eyes) was followed up without treatment. BCVA and CMT by OCT were analyzed at baseline and 3 and 6 months. Additionally, parameters such as the vessel de…

Œdème maculaire diabétique : diagnostic et bilan pré-thérapeutique

2015

Tears as a source of biomarkers for ocular and systemic diseases

2013

The main focus in clinical proteomics is the discovery of new protein or peptide biomarkers which are correlated with a certain disease. Tear proteins have been investigated extensively in the past and distinct relations between the levels of certain tear proteins to different disorders have been demonstrated. In this review we attempt to summarize proteomic technologies for biomarker identification in tears and some disease related biomarkers in tear fluids that were discovered through different proteomic techniques in different conditions like dry eye, Sjogren's syndrome, contact lens wearers, glaucoma, diabetic retinopathy or cancer. Proteomic analysis of tear fluid has proven to be a pr…

Microaneurysm detection with radon transform-based classification on retina images.

2012

The creation of an automatic diabetic retinopathy screening system using retina cameras is currently receiving considerable interest in the medical imaging community. The detection of microaneurysms is a key element in this effort. In this work, we propose a new microaneurysms segmentation technique based on a novel application of the radon transform, which is able to identify these lesions without any previous knowledge of the retina morphological features and with minimal image preprocessing. The algorithm has been evaluated on the Retinopathy Online Challenge public dataset, and its performance compares with the best current techniques. The performance is particularly good at low false p…