Search results for "Difference"
showing 10 items of 1534 documents
Cancer antigen-125 and risk of atrial fibrillation: a systematic review and meta-analysis
2017
WOS: 000458034100002
Biomarker testing of lung cancer in Spain
2019
Abstract Background Target therapy guide by biomarkers have become the standard of care for patients with lung cancer (LC). So, identify those molecular alterations is one of the most important care needs nowdays. Our objective was to know the implementation degree of these tests in a large cohort of patients in Spain using the Thoracic Tumor Registry (TTR) of the Grupo Espanol de Cancer de Pulmon (Spanish Lung Cancer Group). Methods The TTR is an observational cohort multicenter study of LC in Spain. The study is conducted according to the Declaration of Helsinki and approved by the institutional review board of each participating institute. The registry was approved by the Spanish Drug Ag…
POS1021 THE PsABio STUDY IN ITALY: A REAL-WORLD COMPARISON OF THE PERSISTENCE, EFFECTIVENESS AND SAFETY OF USTEKINUMAB AND TUMOUR NECROSIS FACTOR INH…
2021
Background:There are still unmet needs in the treatment of psoriatic arthritis (PsA), including in terms of treatment persistence, which is a function of effectiveness, safety and patient satisfaction. Ustekinumab (UST) was the first new biologic drug to be developed for the treatment of PsA after tumour necrosis factor inhibitors (TNFi).Objectives:To compare treatment persistence, effectiveness and safety of UST and TNFi in Italian patients within the PsABio cohort.Methods:PsABio (NCT02627768) is an observational study of 1st/2nd/3rd-line UST or TNFi treatment in PsA in 8 European countries. The current analysis set includes 222 eligible patients treated in 15 Italian centres, followed to …
Clinical pain evaluation with intraoral vibration device during local anesthetic injections
2014
Objectives: To evaluate the clinical pain during local anesthetic injection using such intra-oral device. Study Design: A comparative split-mouth clinical study to evaluate clinical pain was conducted among the subjects who required bilateral local anesthetic intra-oral injections. Results: A total of 99 subjects participated in the study out of which 39 were female. A total of 256 local anesthetic injections were administered to all the subjects with at least one pair of similar local anesthetic injections. Comparison of mean VAS score for anticipated pain in without vibration group was significantly higher in all types of nerve blocks when compared to that of with vibration. Similarly, th…
REGIONAL DIFFERENCES IN BICEPS FEMORIS FASCICLE LENGTH AND PENNATION ANGLE AFTER A SIMULATED SOCCER MATCH
2017
Background Hamstring Strain Injuries (HSIs) represent 12% of all injuries in soccer players, and their incidence has increased in recent years. Between 53%-84% of HSIs involve the Biceps femoris muscle (BF). Recent studies have shown that soccer players with shorter BF fascicle length (FL) suffer more HSIs and exhibit regional differences in FL and pennation angle (PA) along BF. It is unclear whether there is any regional difference in the degree of change of these parameters after a soccer match. Objective Describe changes in BF muscle architecture after a simulated soccer match. Design Controlled laboratory study. Pre and Post single session. Setting Laboratory. Amateur Level. Participant…
Hyaluronic Acid in the Treatment of Pain Due to Knee Joint Immobilisation
1995
This open, randomised study was carried out in order to evaluate the safety and efficacy of a course of 5 intra-articular injections (one per week) of hyaluronic acid (HA), administered to patients with pain and joint stiffness resulting from immobilisation of the knee in a plaster cast. The study was made in comparison with an untreated control group. 30 patients of both genders, aged between 18 and 65 years, immobilised in a plaster cast for at least 20 days and presenting with pain and reduced mobility, were included in the study. The results of the study show that, in comparison with the control group, treatment with HA produced a more rapid and effective reduction in pain and increase …
Directly measured and self-reported physical activity in a sample of Finnish secondary school students
2012
Previous studies based on self-reports show that a majority of children and adolescents in Western countries fail to achieve the recommendation of 60 minutes moderate to vigorous physical activity (PA) on a daily basis. The specific aim of the study was to analyze the relationship between directly measured and self-reported PA in a cross-sectional sample of Finnish secondary school students. Moreover, how large proportion of adolescents accumulate at least 60 minutes of moderate to vigorous PA on a daily basis using self-reports and direct measure scores. Methods: Participants were recruited from a secondary school located in Northeast Finland. The sample comprised 96 students (58 girls, 38…
Study of gender differences in VR response following cardiac surgery.
2017
Cardiac and other invasive surgical procedures cause significant anxiety and stress to patients and their family members. In this study Virtual Reality (VR) was used as a method to reduce stress, anxiety and pain in patients undergoing surgical procedures. This study compared a cohort of patients in the interval prior to and successive to the surgery, differentiating the responses achieved by males and females and comparing the effectiveness. The results are encouraging: they demonstrate the efficacy of VR treatment and the safety of the method and detection of differences in the responses based on gender.
Effects of exercise training on oxygen uptake in coronary heart disease: a systematic review and meta-analysis
2010
It is not known to what extent exercise programs increase maximal oxygen uptake (VO(2max)) in patients with coronary heart diseases (CHD). The purpose of this study is to determine the effect of exercise interventions on VO(2max) in subjects with CHD. Database search of randomized controlled trials was conducted from PubMed. Studies were included that reported the characteristics and effects of exercise interventions in subjects with CHD, included a non-exercise control group and measured VO(2max) using direct measurement method. Eighteen studies were eligible. Exercise interventions increased VO(2max) by 2.6 +/- 1.6 and 0.3 +/- 1.4 mL/kg/min in the training and control groups, respectively…
Mometasone furoate delivered via Breezhaler and Twisthaler in patients with asthma
2019
Introduction: Mometasone furoate (MF), an inhaled corticosteroid (ICS), is approved for the treatment of asthma. Previous studies suggest that MF Twisthaler® doses of 800 and 200 µg and MF Breezhaler® doses of 320 and 80 µg would elicit similar lung function effects, respectively. These MF doses are also used in an indacaterol/MF combination in development for asthma. Since sensitivity to ICS is variable, individual patients’ ICS sensitivity (as measured by FEV1 decline on ICS weaning) was used to build a robust analysis model for the study data. Methods: This was a randomized, double-blind, double-dummy, parallel-group, non-inferiority study of 739 adolescents and adults with asthma. MF wa…